Identifying the lungs as a susceptible site for allele-specific regulatory changes associated with type 1 diabetes risk.
Communications Biology
Ho, Daniel D; Nyaga, Denis M DM; Schierding, William W; Saffery, Richard R; Perry, Jo K JK; Taylor, John A JA; Vickers, Mark H MH; Kempa-Liehr, Andreas W AW; O'Sullivan, Justin M JM
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis.
Nature Communications
Xie, Jingyuan J; Liu, Lili L; Mladkova, Nikol N; Li, Yifu Y; Ren, Hong H; Wang, Weiming W; Cui, Zhao Z; Lin, Li L; Hu, Xiaofan X; Yu, Xialian X; Xu, Jing J; Liu, Gang G; Caliskan, Yasar Y; Sidore, Carlo C; Balderes, Olivia O; Rosen, Raphael J RJ; Bodria, Monica M; Zanoni, Francesca F; Zhang, Jun Y JY; Krithivasan, Priya P; Mehl, Karla K; Marasa, Maddalena M; Khan, Atlas A; Ozay, Fatih F; Canetta, Pietro A PA; Bomback, Andrew S AS; Appel, Gerald B GB; Sanna-Cherchi, Simone S; Sampson, Matthew G MG; Mariani, Laura H LH; Perkowska-Ptasinska, Agnieszka A; Durlik, Magdalena M; Mucha, Krzysztof K; Moszczuk, Barbara B; Foroncewicz, Bartosz B; Pączek, Leszek L; Habura, Ireneusz I; Ars, Elisabet E; Ballarin, Jose J; Mani, Laila-Yasmin LY; Vogt, Bruno B; Ozturk, Savas S; Yildiz, Abdülmecit A; Seyahi, Nurhan N; Arikan, Hakki H; Koc, Mehmet M; Basturk, Taner T; Karahan, Gonca G; Akgul, Sebahat Usta SU; Sever, Mehmet Sukru MS; Zhang, Dan D; Santoro, Domenico D; Bonomini, Mario M; Londrino, Francesco F; Gesualdo, Loreto L; Reiterova, Jana J; Tesar, Vladimir V; Izzi, Claudia C; Savoldi, Silvana S; Spotti, Donatella D; Marcantoni, Carmelita C; Messa, Piergiorgio P; Galliani, Marco M; Roccatello, Dario D; Granata, Simona S; Zaza, Gianluigi G; Lugani, Francesca F; Ghiggeri, GianMarco G; Pisani, Isabella I; Allegri, Landino L; Sprangers, Ben B; Park, Jin-Ho JH; Cho, BeLong B; Kim, Yon Su YS; Kim, Dong Ki DK; Suzuki, Hitoshi H; Amoroso, Antonio A; Cattran, Daniel C DC; Fervenza, Fernando C FC; Pani, Antonello A; Hamilton, Patrick P; Harris, Shelly S; Gupta, Sanjana S; Cheshire, Chris C; Dufek, Stephanie S; Issler, Naomi N; Pepper, Ruth J RJ; Connolly, John J; Powis, Stephen S; Bockenhauer, Detlef D; Stanescu, Horia C HC; Ashman, Neil N; Loos, Ruth J F RJF; Kenny, Eimear E EE; Wuttke, Matthias M; Eckardt, Kai-Uwe KU; Köttgen, Anna A; Hofstra, Julia M JM; Coenen, Marieke J H MJH; Kiemeney, Lambertus A LA; Akilesh, Shreeram S; Kretzler, Matthias M; Beck, Lawrence H LH; Stengel, Benedicte B; Debiec, Hanna H; Ronco, Pierre P; Wetzels, Jack F M JFM; Zoledziewska, Magdalena M; Cucca, Francesco F; Ionita-Laza, Iuliana I; Lee, Hajeong H; Hoxha, Elion E; Stahl, Rolf A K RAK; Brenchley, Paul P; Scolari, Francesco F; Zhao, Ming-Hui MH; Gharavi, Ali G AG; Kleta, Robert R; Chen, Nan N; Kiryluk, Krzysztof K
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
Plos Genetics
Ramdhani, Satesh S; Navarro, Elisa E; Udine, Evan E; Efthymiou, Anastasia G AG; Schilder, Brian M BM; Parks, Madison M; Goate, Alison A; Raj, Towfique T
Genetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.
Diabetes
Aydemir, Özkan Ö; Noble, Janelle A JA; Bailey, Jeffrey A JA; Lernmark, Åke Å; Marsh, Patrick P; Andersson Svärd, Agnes A; Bearoff, Frank F; Blankenhorn, Elizabeth P EP; Mordes, John P JP; ,
Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.
Journal Of Diabetes Research
Brorsson, Caroline A CA; Nielsen, Lotte B LB; Andersen, Marie Louise ML; Kaur, Simranjeet S; Bergholdt, Regine R; Hansen, Lars L; Mortensen, Henrik B HB; Pociot, Flemming F; Størling, Joachim J; ,
Heritability and genomics of gene expression in peripheral blood.
Nature Genetics
Wright, Fred A FA; Sullivan, Patrick F PF; Brooks, Andrew I AI; Zou, Fei F; Sun, Wei W; Xia, Kai K; Madar, Vered V; Jansen, Rick R; Chung, Wonil W; Zhou, Yi-Hui YH; Abdellaoui, Abdel A; Batista, Sandra S; Butler, Casey C; Chen, Guanhua G; Chen, Ting-Huei TH; D'Ambrosio, David D; Gallins, Paul P; Ha, Min Jin MJ; Hottenga, Jouke Jan JJ; Huang, Shunping S; Kattenberg, Mathijs M; Kochar, Jaspreet J; Middeldorp, Christel M CM; Qu, Ani A; Shabalin, Andrey A; Tischfield, Jay J; Todd, Laura L; Tzeng, Jung-Ying JY; van Grootheest, Gerard G; Vink, Jacqueline M JM; Wang, Qi Q; Wang, Wei W; Wang, Weibo W; Willemsen, Gonneke G; Smit, Johannes H JH; de Geus, Eco J EJ; Yin, Zhaoyu Z; Penninx, Brenda W J H BW; Boomsma, Dorret I DI
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Nature Genetics
, ; , ; , ; , ; , ; Mahajan, Anubha A; Go, Min Jin MJ; Zhang, Weihua W; Below, Jennifer E JE; Gaulton, Kyle J KJ; Ferreira, Teresa T; Horikoshi, Momoko M; Johnson, Andrew D AD; Ng, Maggie C Y MC; Prokopenko, Inga I; Saleheen, Danish D; Wang, Xu X; Zeggini, Eleftheria E; Abecasis, Goncalo R GR; Adair, Linda S LS; Almgren, Peter P; Atalay, Mustafa M; Aung, Tin T; Baldassarre, Damiano D; Balkau, Beverley B; Bao, Yuqian Y; Barnett, Anthony H AH; Barroso, Ines I; Basit, Abdul A; Been, Latonya F LF; Beilby, John J; Bell, Graeme I GI; Benediktsson, Rafn R; Bergman, Richard N RN; Boehm, Bernhard O BO; Boerwinkle, Eric E; Bonnycastle, Lori L LL; Burtt, Noël N; Cai, Qiuyin Q; Campbell, Harry H; Carey, Jason J; Cauchi, Stephane S; Caulfield, Mark M; Chan, Juliana C N JC; Chang, Li-Ching LC; Chang, Tien-Jyun TJ; Chang, Yi-Cheng YC; Charpentier, Guillaume G; Chen, Chien-Hsiun CH; Chen, Han H; Chen, Yuan-Tsong YT; Chia, Kee-Seng KS; Chidambaram, Manickam M; Chines, Peter S PS; Cho, Nam H NH; Cho, Young Min YM; Chuang, Lee-Ming LM; Collins, Francis S FS; Cornelis, Marylin C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Danesh, John J; Das, Debashish D; de Faire, Ulf U; Dedoussis, George G; Deloukas, Panos P; Dimas, Antigone S AS; Dina, Christian C; Doney, Alex S AS; Donnelly, Peter J PJ; Dorkhan, Mozhgan M; van Duijn, Cornelia C; Dupuis, Josée J; Edkins, Sarah S; Elliott, Paul P; Emilsson, Valur V; Erbel, Raimund R; Eriksson, Johan G JG; Escobedo, Jorge J; Esko, Tonu T; Eury, Elodie E; Florez, Jose C JC; Fontanillas, Pierre P; Forouhi, Nita G NG; Forsen, Tom T; Fox, Caroline C; Fraser, Ross M RM; Frayling, Timothy M TM; Froguel, Philippe P; Frossard, Philippe P; Gao, Yutang Y; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Grallert, Harald H; Grant, George B GB; Grrop, Leif C LC; Groves, Chrisropher J CJ; Grundberg, Elin E; Guiducci, Candace C; Hamsten, Anders A; Han, Bok-Ghee BG; Hara, Kazuo K; Hassanali, Neelam N; Hattersley, Andrew T AT; Hayward, Caroline C; Hedman, Asa K AK; Herder, Christian C; Hofman, Albert A; Holmen, Oddgeir L OL; Hovingh, Kees K; Hreidarsson, Astradur B AB; Hu, Cheng C; Hu, Frank B FB; Hui, Jennie J; Humphries, Steve E SE; Hunt, Sarah E SE; Hunter, David J DJ; Hveem, Kristian K; Hydrie, Zafar I ZI; Ikegami, Hiroshi H; Illig, Thomas T; Ingelsson, Erik E; Islam, Muhammed M; Isomaa, Bo B; Jackson, Anne U AU; Jafar, Tazeen T; James, Alan A; Jia, Weiping W; Jöckel, Karl-Heinz KH; Jonsson, Anna A; Jowett, Jeremy B M JB; Kadowaki, Takashi T; Kang, Hyun Min HM; Kanoni, Stavroula S; Kao, Wen Hong L WH; Kathiresan, Sekar S; Kato, Norihiro N; Katulanda, Prasad P; Keinanen-Kiukaanniemi, Kirkka M KM; Kelly, Ann M AM; Khan, Hassan H; Khaw, Kay-Tee KT; Khor, Chiea-Chuen CC; Kim, Hyung-Lae HL; Kim, Sangsoo S; Kim, Young Jin YJ; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Korpi-Hyövälti, Eeva E; Kowlessur, Sudhir S; Kraft, Peter P; Kravic, Jasmina J; Kristensen, Malene M MM; Krithika, S S; Kumar, Ashish A; Kumate, Jesus J; Kuusisto, Johanna J; Kwak, Soo Heon SH; Laakso, Markku M; Lagou, Vasiliki V; Lakka, Timo A TA; Langenberg, Claudia C; Langford, Cordelia C; Lawrence, Robert R; Leander, Karin K; Lee, Jen-Mai JM; Lee, Nanette R NR; Li, Man M; Li, Xinzhong X; Li, Yun Y; Liang, Junbin J; Liju, Samuel S; Lim, Wei-Yen WY; Lind, Lars L; Lindgren, Cecilia M CM; Lindholm, Eero E; Liu, Ching-Ti CT; Liu, Jian Jun JJ; Lobbens, Stéphane S; Long, Jirong J; Loos, Ruth J F RJ; Lu, Wei W; Luan, Jian'an J; Lyssenko, Valeriya V; Ma, Ronald C W RC; Maeda, Shiro S; Mägi, Reedik R; Männisto, Satu S; Matthews, David R DR; Meigs, James B JB; Melander, Olle O; Metspalu, Andres A; Meyer, Julia J; Mirza, Ghazala G; Mihailov, Evelin E; Moebus, Susanne S; Mohan, Viswanathan V; Mohlke, Karen L KL; Morris, Andrew D AD; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Musk, Bill B; Nakamura, Jiro J; Nakashima, Eitaro E; Navarro, Pau P; Ng, Peng-Keat PK; Nica, Alexandra C AC; Nilsson, Peter M PM; Njølstad, Inger I; Nöthen, Markus M MM; Ohnaka, Keizo K; Ong, Twee Hee TH; Owen, Katharine R KR; Palmer, Colin N A CN; Pankow, James S JS; Park, Kyong Soo KS; Parkin, Melissa M; Pechlivanis, Sonali S; Pedersen, Nancy L NL; Peltonen, Leena L; Perry, John R B JR; Peters, Annette A; Pinidiyapathirage, Janini M JM; Platou, Carl G CG; Potter, Simon S; Price, Jackie F JF; Qi, Lu L; Radha, Venkatesan V; Rallidis, Loukianos L; Rasheed, Asif A; Rathman, Wolfgang W; Rauramaa, Rainer R; Raychaudhuri, Soumya S; Rayner, N William NW; Rees, Simon D SD; Rehnberg, Emil E; Ripatti, Samuli S; Robertson, Neil N; Roden, Michael M; Rossin, Elizabeth J EJ; Rudan, Igor I; Rybin, Denis D; Saaristo, Timo E TE; Salomaa, Veikko V; Saltevo, Juha J; Samuel, Maria M; Sanghera, Dharambir K DK; Saramies, Jouko J; Scott, James J; Scott, Laura J LJ; Scott, Robert A RA; Segrè, Ayellet V AV; Sehmi, Joban J; Sennblad, Bengt B; Shah, Nabi N; Shah, Sonia S; Shera, A Samad AS; Shu, Xiao Ou XO; Shuldiner, Alan R AR; Sigurđsson, Gunnar G; Sijbrands, Eric E; Silveira, Angela A; Sim, Xueling X; Sivapalaratnam, Suthesh S; Small, Kerrin S KS; So, Wing Yee WY; Stančáková, Alena A; Stefansson, Kari K; Steinbach, Gerald G; Steinthorsdottir, Valgerdur V; Stirrups, Kathleen K; Strawbridge, Rona J RJ; Stringham, Heather M HM; Sun, Qi Q; Suo, Chen C; Syvänen, Ann-Christine AC; Takayanagi, Ryoichi R; Takeuchi, Fumihiko F; Tay, Wan Ting WT; Teslovich, Tanya M TM; Thorand, Barbara B; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Tikkanen, Emmi E; Trakalo, Joseph J; Tremoli, Elena E; Trip, Mieke D MD; Tsai, Fuu Jen FJ; Tuomi, Tiinamaija T; Tuomilehto, Jaakko J; Uitterlinden, Andre G AG; Valladares-Salgado, Adan A; Vedantam, Sailaja S; Veglia, Fabrizio F; Voight, Benjamin F BF; Wang, Congrong C; Wareham, Nicholas J NJ; Wennauer, Roman R; Wickremasinghe, Ananda R AR; Wilsgaard, Tom T; Wilson, James F JF; Wiltshire, Steven S; Winckler, Wendy W; Wong, Tien Yin TY; Wood, Andrew R AR; Wu, Jer-Yuarn JY; Wu, Ying Y; Yamamoto, Ken K; Yamauchi, Toshimasa T; Yang, Mingyu M; Yengo, Loic L; Yokota, Mitsuhiro M; Young, Robin R; Zabaneh, Delilah D; Zhang, Fan F; Zhang, Rong R; Zheng, Wei W; Zimmet, Paul Z PZ; Altshuler, David D; Bowden, Donald W DW; Cho, Yoon Shin YS; Cox, Nancy J NJ; Cruz, Miguel M; Hanis, Craig L CL; Kooner, Jaspal J; Lee, Jong-Young JY; Seielstad, Mark M; Teo, Yik Ying YY; Boehnke, Michael M; Parra, Esteban J EJ; Chambers, Jonh C JC; Tai, E Shyong ES; McCarthy, Mark I MI; Morris, Andrew P AP
Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.
Human Genetics
Falah, Nadia N; McElroy, Jude J; Snegovskikh, Victoria V; Lockwood, Charles J CJ; Norwitz, Errol E; Murray, Jeffey C JC; Kuczynski, Edward E; Menon, Ramkumar R; Teramo, Kari K; Muglia, Louis J LJ; Morgan, Thomas T
Impact of common variation in bone-related genes on type 2 diabetes and related traits.
Diabetes
Billings, Liana K LK; Hsu, Yi-Hsiang YH; Ackerman, Rachel J RJ; Dupuis, Josée J; Voight, Benjamin F BF; Rasmussen-Torvik, Laura J LJ; Hercberg, Serge S; Lathrop, Mark M; Barnes, Daniel D; Langenberg, Claudia C; Hui, Jennie J; Fu, Mao M; Bouatia-Naji, Nabila N; Lecoeur, Cecile C; An, Ping P; Magnusson, Patrik K PK; Surakka, Ida I; Ripatti, Samuli S; Christiansen, Lene L; Dalgård, Christine C; Folkersen, Lasse L; Grundberg, Elin E; , ; , ; , ; , ; , ; Eriksson, Per P; Kaprio, Jaakko J; Ohm Kyvik, Kirsten K; Pedersen, Nancy L NL; Borecki, Ingrid B IB; Province, Michael A MA; Balkau, Beverley B; Froguel, Philippe P; Shuldiner, Alan R AR; Palmer, Lyle J LJ; Wareham, Nick N; Meneton, Pierre P; Johnson, Toby T; Pankow, James S JS; Karasik, David D; Meigs, James B JB; Kiel, Douglas P DP; Florez, Jose C JC
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
Plos Genetics
Bradfield, Jonathan P JP; Qu, Hui-Qi HQ; Wang, Kai K; Zhang, Haitao H; Sleiman, Patrick M PM; Kim, Cecilia E CE; Mentch, Frank D FD; Qiu, Haijun H; Glessner, Joseph T JT; Thomas, Kelly A KA; Frackelton, Edward C EC; Chiavacci, Rosetta M RM; Imielinski, Marcin M; Monos, Dimitri S DS; Pandey, Rahul R; Bakay, Marina M; Grant, Struan F A SF; Polychronakos, Constantin C; Hakonarson, Hakon H
Pociot, Flemming F; Akolkar, Beena B; Concannon, Patrick P; Erlich, Henry A HA; Julier, Cécile C; Morahan, Grant G; Nierras, Concepcion R CR; Todd, John A JA; Rich, Stephen S SS; Nerup, Jørn J
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Nature Genetics
Barrett, Jeffrey C JC; Clayton, David G DG; Concannon, Patrick P; Akolkar, Beena B; Cooper, Jason D JD; Erlich, Henry A HA; Julier, Cécile C; Morahan, Grant G; Nerup, Jørn J; Nierras, Concepcion C; Plagnol, Vincent V; Pociot, Flemming F; Schuilenburg, Helen H; Smyth, Deborah J DJ; Stevens, Helen H; Todd, John A JA; Walker, Neil M NM; Rich, Stephen S SS; ,