The risk of various types of cardiovascular diseases in mutation positive familial hypercholesterolemia; a review.
Frontiers In Genetics
Hovland, Anders A; Mundal, Liv J LJ; Veierød, Marit B MB; Holven, Kirsten B KB; Bogsrud, Martin Prøven MP; Tell, Grethe S GS; Leren, Trond P TP; Retterstøl, Kjetil K
The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.
Frontiers In Pharmacology
Trompet, Stella S; Postmus, Iris I; Warren, Helen R HR; Noordam, Raymond R; Smit, Roelof A J RAJ; Theusch, Elizabeth E; Li, Xiaohui X; Arsenault, Benoit B; Chasman, Daniel I DI; Hitman, Graham A GA; Munroe, Patricia B PB; Rotter, Jerome I JI; Psaty, Bruce M BM; Caulfield, Mark J MJ; Krauss, Ron M RM; Cupples, Adrienne L AL; Jukema, Wouter J WJ
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.
Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study.
Frontiers In Cardiovascular Medicine
Knowles, Joshua W JW; Zarafshar, Shirin S; Pavlovic, Aleksandra A; Goldstein, Benjamin A BA; Tsai, Sandra S; Li, Jin J; McConnell, Michael V MV; Absher, Devin D; Ashley, Euan A EA; Kiernan, Michaela M; Ioannidis, John P A JPA; Assimes, Themistocles L TL
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
Plos Genetics
Byars, Sean G SG; Huang, Qin Qin QQ; Gray, Lesley-Ann LA; Bakshi, Andrew A; Ripatti, Samuli S; Abraham, Gad G; Stearns, Stephen C SC; Inouye, Michael M
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.
Genome Biology
Joehanes, Roby R; Zhang, Xiaoling X; Huan, Tianxiao T; Yao, Chen C; Ying, Sai-Xia SX; Nguyen, Quang Tri QT; Demirkale, Cumhur Yusuf CY; Feolo, Michael L ML; Sharopova, Nataliya R NR; Sturcke, Anne A; Schäffer, Alejandro A AA; Heard-Costa, Nancy N; Chen, Han H; Liu, Po-Ching PC; Wang, Richard R; Woodhouse, Kimberly A KA; Tanriverdi, Kahraman K; Freedman, Jane E JE; Raghavachari, Nalini N; Dupuis, Josée J; Johnson, Andrew D AD; O'Donnell, Christopher J CJ; Levy, Daniel D; Munson, Peter J PJ
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.
Data In Brief
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
Lancet (London, England)
Mega, J L JL; Stitziel, N O NO; Smith, J G JG; Chasman, D I DI; Caulfield, M M; Devlin, J J JJ; Nordio, F F; Hyde, C C; Cannon, C P CP; Sacks, F F; Poulter, N N; Sever, P P; Ridker, P M PM; Braunwald, E E; Melander, O O; Kathiresan, S S; Sabatine, M S MS
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach.
European Journal Of Human Genetics : Ejhg
Versmissen, Jorie J; Oosterveer, Daniëlla M DM; Yazdanpanah, Mojgan M; Dehghan, Abbas A; Hólm, Hilma H; Erdman, Jeanette J; Aulchenko, Yurii S YS; Thorleifsson, Gudmar G; Schunkert, Heribert H; Huijgen, Roeland R; Vongpromek, Ranitha R; Uitterlinden, André G AG; Defesche, Joep C JC; van Duijn, Cornelia M CM; Mulder, Monique M; Dadd, Tony T; Karlsson, Hróbjartur D HD; Ordovas, Jose J; Kindt, Iris I; Jarman, Amelia A; Hofman, Albert A; van Vark-van der Zee, Leonie L; Blommesteijn-Touw, Adriana C AC; Kwekkeboom, Jaap J; Liem, Anho H AH; van der Ouderaa, Frans J FJ; Calandra, Sebastiano S; Bertolini, Stefano S; Averna, Maurizio M; Langslet, Gisle G; Ose, Leiv L; Ros, Emilio E; Almagro, Fátima F; de Leeuw, Peter W PW; Civeira, Fernando F; Masana, Luis L; Pintó, Xavier X; Simoons, Maarten L ML; Schinkel, Arend F L AF; Green, Martin R MR; Zwinderman, Aeilko H AH; Johnson, Keith J KJ; Schaefer, Arne A; Neil, Andrew A; Witteman, Jacqueline C M JC; Humphries, Steve E SE; Kastelein, John J P JJ; Sijbrands, Eric J G EJ
Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.
Atherosclerosis
Simino, Jeannette J; Kume, Rezart R; Kraja, Aldi T AT; Turner, Stephen T ST; Hanis, Craig L CL; Sheu, Wayne W; Chen, Ida I; Jaquish, Cashell C; Cooper, Richard S RS; Chakravarti, Aravinda A; Quertermous, Thomas T; Boerwinkle, Eric E; Hunt, Steven C SC; Rao, D C DC
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation
Olden, Matthias M; Teumer, Alexander A; Bochud, Murielle M; Pattaro, Cristian C; Köttgen, Anna A; Turner, Stephen T ST; Rettig, Rainer R; Chen, Ming-Huei MH; Dehghan, Abbas A; Bastardot, Francois F; Schmidt, Reinhold R; Vollenweider, Peter P; Schunkert, Heribert H; Reilly, Muredach P MP; Fornage, Myriam M; Launer, Lenore J LJ; Verwoert, Germaine C GC; Mitchell, Gary F GF; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Cheng, Ching-Yu CY; Sim, Xueling X; Siscovick, David S DS; Coresh, Josef J; Kao, W H Linda WH; Fox, Caroline S CS; O'Seaghdha, Conall M CM; ,
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Borden, William B WB; Bravata, Dawn M DM; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Magid, David D; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Nichol, Graham G; Paynter, Nina P NP; Schreiner, Pamela J PJ; Sorlie, Paul D PD; Stein, Joel J; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Large-scale association analysis identifies new risk loci for coronary artery disease.
Nature Genetics
, ; Deloukas, Panos P; Kanoni, Stavroula S; Willenborg, Christina C; Farrall, Martin M; Assimes, Themistocles L TL; Thompson, John R JR; Ingelsson, Erik E; Saleheen, Danish D; Erdmann, Jeanette J; Goldstein, Benjamin A BA; Stirrups, Kathleen K; König, Inke R IR; Cazier, Jean-Baptiste JB; Johansson, Asa A; Hall, Alistair S AS; Lee, Jong-Young JY; Willer, Cristen J CJ; Chambers, John C JC; Esko, Tõnu T; Folkersen, Lasse L; Goel, Anuj A; Grundberg, Elin E; Havulinna, Aki S AS; Ho, Weang K WK; Hopewell, Jemma C JC; Eriksson, Niclas N; Kleber, Marcus E ME; Kristiansson, Kati K; Lundmark, Per P; Lyytikäinen, Leo-Pekka LP; Rafelt, Suzanne S; Shungin, Dmitry D; Strawbridge, Rona J RJ; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Van Zuydam, Natalie N; Voight, Benjamin F BF; Waite, Lindsay L LL; Zhang, Weihua W; Ziegler, Andreas A; Absher, Devin D; Altshuler, David D; Balmforth, Anthony J AJ; Barroso, Inês I; Braund, Peter S PS; Burgdorf, Christof C; Claudi-Boehm, Simone S; Cox, David D; Dimitriou, Maria M; Do, Ron R; , ; , ; Doney, Alex S F AS; El Mokhtari, NourEddine N; Eriksson, Per P; Fischer, Krista K; Fontanillas, Pierre P; Franco-Cereceda, Anders A; Gigante, Bruna B; Groop, Leif L; Gustafsson, Stefan S; Hager, Jörg J; Hallmans, Göran G; Han, Bok-Ghee BG; Hunt, Sarah E SE; Kang, Hyun M HM; Illig, Thomas T; Kessler, Thorsten T; Knowles, Joshua W JW; Kolovou, Genovefa G; Kuusisto, Johanna J; Langenberg, Claudia C; Langford, Cordelia C; Leander, Karin K; Lokki, Marja-Liisa ML; Lundmark, Anders A; McCarthy, Mark I MI; Meisinger, Christa C; Melander, Olle O; Mihailov, Evelin E; Maouche, Seraya S; Morris, Andrew D AD; Müller-Nurasyid, Martina M; , ; Nikus, Kjell K; Peden, John F JF; Rayner, N William NW; Rasheed, Asif A; Rosinger, Silke S; Rubin, Diana D; Rumpf, Moritz P MP; Schäfer, Arne A; Sivananthan, Mohan M; Song, Ci C; Stewart, Alexandre F R AF; Tan, Sian-Tsung ST; Thorgeirsson, Gudmundur G; van der Schoot, C Ellen CE; Wagner, Peter J PJ; , ; Wells, George A GA; Wild, Philipp S PS; Yang, Tsun-Po TP; Amouyel, Philippe P; Arveiler, Dominique D; Basart, Hanneke H; Boehnke, Michael M; Boerwinkle, Eric E; Brambilla, Paolo P; Cambien, Francois F; Cupples, Adrienne L AL; de Faire, Ulf U; Dehghan, Abbas A; Diemert, Patrick P; Epstein, Stephen E SE; Evans, Alun A; Ferrario, Marco M MM; Ferrières, Jean J; Gauguier, Dominique D; Go, Alan S AS; Goodall, Alison H AH; Gudnason, Villi V; Hazen, Stanley L SL; Holm, Hilma H; Iribarren, Carlos C; Jang, Yangsoo Y; Kähönen, Mika M; Kee, Frank F; Kim, Hyo-Soo HS; Klopp, Norman N; Koenig, Wolfgang W; Kratzer, Wolfgang W; Kuulasmaa, Kari K; Laakso, Markku M; Laaksonen, Reijo R; Lee, Ji-Young JY; Lind, Lars L; Ouwehand, Willem H WH; Parish, Sarah S; Park, Jeong E JE; Pedersen, Nancy L NL; Peters, Annette A; Quertermous, Thomas T; Rader, Daniel J DJ; Salomaa, Veikko V; Schadt, Eric E; Shah, Svati H SH; Sinisalo, Juha J; Stark, Klaus K; Stefansson, Kari K; Trégouët, David-Alexandre DA; Virtamo, Jarmo J; Wallentin, Lars L; Wareham, Nicholas N; Zimmermann, Martina E ME; Nieminen, Markku S MS; Hengstenberg, Christian C; Sandhu, Manjinder S MS; Pastinen, Tomi T; Syvänen, Ann-Christine AC; Hovingh, G Kees GK; Dedoussis, George G; Franks, Paul W PW; Lehtimäki, Terho T; Metspalu, Andres A; Zalloua, Pierre A PA; Siegbahn, Agneta A; Schreiber, Stefan S; Ripatti, Samuli S; Blankenberg, Stefan S SS; Perola, Markus M; Clarke, Robert R; Boehm, Bernhard O BO; O'Donnell, Christopher C; Reilly, Muredach P MP; März, Winfried W; Collins, Rory R; Kathiresan, Sekar S; Hamsten, Anders A; Kooner, Jaspal S JS; Thorsteinsdottir, Unnur U; Danesh, John J; Palmer, Colin N A CN; Roberts, Robert R; Watkins, Hugh H; Schunkert, Heribert H; Samani, Nilesh J NJ
Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.
Plos One
Lucas, Gavin G; Lluís-Ganella, Carla C; Subirana, Isaac I; Musameh, Muntaser D MD; Gonzalez, Juan Ramon JR; Nelson, Christopher P CP; Sentí, Mariano M; , ; , ; Schwartz, Stephen M SM; Siscovick, David D; O'Donnell, Christopher J CJ; Melander, Olle O; Salomaa, Veikko V; Purcell, Shaun S; Altshuler, David D; Samani, Nilesh J NJ; Kathiresan, Sekar S; Elosua, Roberto R
Randomized trial of personal genomics for preventive cardiology: design and challenges.
Circulation. Cardiovascular Genetics
Knowles, Joshua W JW; Assimes, Themistocles L TL; Kiernan, Michaela M; Pavlovic, Aleksandra A; Goldstein, Benjamin A BA; Yank, Veronica V; McConnell, Michael V MV; Absher, Devin D; Bustamante, Carlos C; Ashley, Euan A EA; Ioannidis, John P A JP
Heart disease and stroke statistics--2012 update: a report from the American Heart Association.
Circulation
Roger, Véronique L VL; Go, Alan S AS; Lloyd-Jones, Donald M DM; Benjamin, Emelia J EJ; Berry, Jarett D JD; Borden, William B WB; Bravata, Dawn M DM; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Makuc, Diane M DM; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; Moy, Claudia S CS; Mozaffarian, Dariush D; Mussolino, Michael E ME; Nichol, Graham G; Paynter, Nina P NP; Soliman, Elsayed Z EZ; Sorlie, Paul D PD; Sotoodehnia, Nona N; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Nature Genetics
Schunkert, Heribert H; König, Inke R IR; Kathiresan, Sekar S; Reilly, Muredach P MP; Assimes, Themistocles L TL; Holm, Hilma H; Preuss, Michael M; Stewart, Alexandre F R AF; Barbalic, Maja M; Gieger, Christian C; Absher, Devin D; Aherrahrou, Zouhair Z; Allayee, Hooman H; Altshuler, David D; Anand, Sonia S SS; Andersen, Karl K; Anderson, Jeffrey L JL; Ardissino, Diego D; Ball, Stephen G SG; Balmforth, Anthony J AJ; Barnes, Timothy A TA; Becker, Diane M DM; Becker, Lewis C LC; Berger, Klaus K; Bis, Joshua C JC; Boekholdt, S Matthijs SM; Boerwinkle, Eric E; Braund, Peter S PS; Brown, Morris J MJ; Burnett, Mary Susan MS; Buysschaert, Ian I; , ; Carlquist, John F JF; Chen, Li L; Cichon, Sven S; Codd, Veryan V; Davies, Robert W RW; Dedoussis, George G; Dehghan, Abbas A; Demissie, Serkalem S; Devaney, Joseph M JM; Diemert, Patrick P; Do, Ron R; Doering, Angela A; Eifert, Sandra S; Mokhtari, Nour Eddine El NE; Ellis, Stephen G SG; Elosua, Roberto R; Engert, James C JC; Epstein, Stephen E SE; de Faire, Ulf U; Fischer, Marcus M; Folsom, Aaron R AR; Freyer, Jennifer J; Gigante, Bruna B; Girelli, Domenico D; Gretarsdottir, Solveig S; Gudnason, Vilmundur V; Gulcher, Jeffrey R JR; Halperin, Eran E; Hammond, Naomi N; Hazen, Stanley L SL; Hofman, Albert A; Horne, Benjamin D BD; Illig, Thomas T; Iribarren, Carlos C; Jones, Gregory T GT; Jukema, J Wouter JW; Kaiser, Michael A MA; Kaplan, Lee M LM; Kastelein, John J P JJ; Khaw, Kay-Tee KT; Knowles, Joshua W JW; Kolovou, Genovefa G; Kong, Augustine A; Laaksonen, Reijo R; Lambrechts, Diether D; Leander, Karin K; Lettre, Guillaume G; Li, Mingyao M; Lieb, Wolfgang W; Loley, Christina C; Lotery, Andrew J AJ; Mannucci, Pier M PM; Maouche, Seraya S; Martinelli, Nicola N; McKeown, Pascal P PP; Meisinger, Christa C; Meitinger, Thomas T; Melander, Olle O; Merlini, Pier Angelica PA; Mooser, Vincent V; Morgan, Thomas T; Mühleisen, Thomas W TW; Muhlestein, Joseph B JB; Münzel, Thomas T; Musunuru, Kiran K; Nahrstaedt, Janja J; Nelson, Christopher P CP; Nöthen, Markus M MM; Olivieri, Oliviero O; Patel, Riyaz S RS; Patterson, Chris C CC; Peters, Annette A; Peyvandi, Flora F; Qu, Liming L; Quyyumi, Arshed A AA; Rader, Daniel J DJ; Rallidis, Loukianos S LS; Rice, Catherine C; Rosendaal, Frits R FR; Rubin, Diana D; Salomaa, Veikko V; Sampietro, M Lourdes ML; Sandhu, Manj S MS; Schadt, Eric E; Schäfer, Arne A; Schillert, Arne A; Schreiber, Stefan S; Schrezenmeir, Jürgen J; Schwartz, Stephen M SM; Siscovick, David S DS; Sivananthan, Mohan M; Sivapalaratnam, Suthesh S; Smith, Albert A; Smith, Tamara B TB; Snoep, Jaapjan D JD; Soranzo, Nicole N; Spertus, John A JA; Stark, Klaus K; Stirrups, Kathy K; Stoll, Monika M; Tang, W H Wilson WH; Tennstedt, Stephanie S; Thorgeirsson, Gudmundur G; Thorleifsson, Gudmar G; Tomaszewski, Maciej M; Uitterlinden, Andre G AG; van Rij, Andre M AM; Voight, Benjamin F BF; Wareham, Nick J NJ; Wells, George A GA; Wichmann, H-Erich HE; Wild, Philipp S PS; Willenborg, Christina C; Witteman, Jaqueline C M JC; Wright, Benjamin J BJ; Ye, Shu S; Zeller, Tanja T; Ziegler, Andreas A; Cambien, Francois F; Goodall, Alison H AH; Cupples, L Adrienne LA; Quertermous, Thomas T; März, Winfried W; Hengstenberg, Christian C; Blankenberg, Stefan S; Ouwehand, Willem H WH; Hall, Alistair S AS; Deloukas, Panos P; Thompson, John R JR; Stefansson, Kari K; Roberts, Robert R; Thorsteinsdottir, Unnur U; O'Donnell, Christopher J CJ; McPherson, Ruth R; Erdmann, Jeanette J; , ; Samani, Nilesh J NJ