RUNX2 c.182A>T ;(p.Q61L)

Variant ID: 6-45390453-A-T

NM_001024630.3(RUNX2):c.182A>T;(p.Q61L)

This variant was identified in 77 publications

View GRCh38 version.




Publications:


Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity.

Scientific Reports
Pham, Ha H; Hoseini Soflaee, Mona M; Karginov, Andrei V AV; Miller, Lawrence W LW
Publication Date: 2022-03-28

Variant appearance in text: CCD: Q61L
PubMed Link: 35351946
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_9364.pdf
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Akt-mediated Ephexin1-Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation.

Cell Death & Disease
Kim, Jeeho J; Jeon, Young Jin YJ; Lim, Sung-Chul SC; Ryu, Joohyun J; Lee, Jung-Hee JH; Chang, In-Youb IY; You, Ho Jin HJ
Publication Date: 2021-10-28

Variant appearance in text: CCD: Q61L
PubMed Link: 34711817
Variant Present in the following documents:
  • Main text
  • 41419_2021_Article_4332.pdf
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Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma.

The Journal Of Biological Chemistry
Lavictoire, Sylvie J SJ; Jomaa, Danny D; Gont, Alexander A; Jardine, Karen K; Cook, David P DP; Lorimer, Ian A J IAJ
Publication Date: 2021-11

Variant appearance in text: CCD: Q61L
PubMed Link: 34624316
Variant Present in the following documents:
  • Main text
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Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.

Nature Communications
Law, Ah-Lai AL; Jalal, Shamsinar S; Pallett, Tommy T; Mosis, Fuad F; Guni, Ahmad A; Brayford, Simon S; Yolland, Lawrence L; Marcotti, Stefania S; Levitt, James A JA; Poland, Simon P SP; Rowe-Sampson, Maia M; Jandke, Anett A; Köchl, Robert R; Pula, Giordano G; Ameer-Beg, Simon M SM; Stramer, Brian Marc BM; Krause, Matthias M
Publication Date: 2021-09-28

Variant appearance in text: CCD: Q61L
PubMed Link: 34584076
Variant Present in the following documents:
  • Main text
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Impacts of COVID-19 on aircraft usage and fuel consumption: A case study on four Chinese international airports.

Journal Of Air Transport Management
Xue, Dabin D; Liu, Zhizhao Z; Wang, Bing B; Yang, Jian J
Publication Date: 2021-08

Variant appearance in text: CCD: Q61L
PubMed Link: 34548769
Variant Present in the following documents:
  • Main text
  • main.pdf
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Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration.

Elife
Arts, Janine Jg JJ; Mahlandt, Eike K EK; Grönloh, Max Lb ML; Schimmel, Lilian L; Noordstra, Ivar I; Gordon, Emma E; van Steen, Abraham Ci AC; Tol, Simon S; Walzog, Barbara B; van Rijssel, Jos J; Nolte, Martijn A MA; Postma, Marten M; Khuon, Satya S; Heddleston, John M JM; Wait, Eric E; Chew, Teng Leong TL; Winter, Mark M; Montanez, Eloi E; Goedhart, Joachim J; van Buul, Jaap D JD
Publication Date: 2021-08-25

Variant appearance in text: CCD: Q61L
PubMed Link: 34431475
Variant Present in the following documents:
  • Main text
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Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.

Elife
O'Neil, Shataakshi Dube SD; Rácz, Bence B; Brown, Walter Evan WE; Gao, Yudong Y; Soderblom, Erik J EJ; Yasuda, Ryohei R; Soderling, Scott H SH
Publication Date: 2021-07-16

Variant appearance in text: CCD: Q61L
PubMed Link: 34269176
Variant Present in the following documents:
  • Main text
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Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1).

Proceedings Of The National Academy Of Sciences Of The United States Of America
Dietz, Nikolaus N; Huber, Markus M; Sorg, Isabel I; Goepfert, Arnaud A; Harms, Alexander A; Schirmer, Tilman T; Dehio, Christoph C
Publication Date: 2021-03-23

Variant appearance in text: CCD: Q61L
PubMed Link: 33723071
Variant Present in the following documents:
  • Main text
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Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration.

Molecular Biology Of The Cell
Zong, Hailing H; Hazelbaker, Mark M; Moe, Christina C; Ems-McClung, Stephanie C SC; Hu, Ke K; Walczak, Claire E CE
Publication Date: 2021-04-01

Variant appearance in text: CCD: Q61L
PubMed Link: 33566676
Variant Present in the following documents:
  • Main text
  • mbc-32-590.pdf
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Rac and Arp2/3-Nucleated Actin Networks Antagonize Rho During Mitotic and Meiotic Cleavages.

Frontiers In Cell And Developmental Biology
Pal, Debadrita D; Ellis, Andrea A; Sepúlveda-Ramírez, Silvia P SP; Salgado, Torey T; Terrazas, Isabella I; Reyes, Gabriela G; De La Rosa, Richard R; Henson, John H JH; Shuster, Charles B CB
Publication Date: 2020

Variant appearance in text: CCD: Q61L
PubMed Link: 33282870
Variant Present in the following documents:
  • Main text
  • fcell-08-591141.pdf
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RasGRP1 induces autophagy and transformation-associated changes in primary human keratinocytes.

Translational Oncology
Fonseca, Lauren L LL; Yang, Won Seok WS; Geerts, Dirk D; Turkson, James J; Ji, Junfang J; Ramos, Joe W JW
Publication Date: 2021-01

Variant appearance in text: CCD: Q61L
PubMed Link: 33074128
Variant Present in the following documents:
  • Main text
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Differential regulation of rho GTPases during lung adenocarcinoma migration and invasion reveals a novel role of the tumor suppressor StarD13 in invadopodia regulation.

Cell Communication And Signaling : Ccs
Al Haddad, Maria M; El-Rif, Rayane R; Hanna, Samer S; Jaafar, Leila L; Dennaoui, Rayanne R; Abdellatef, Sandra S; Miskolci, Veronika V; Cox, Dianne D; Hodgson, Louis L; El-Sibai, Mirvat M
Publication Date: 2020-09-08

Variant appearance in text: CCD: Q61L
PubMed Link: 32900380
Variant Present in the following documents:
  • Main text
  • 12964_2020_Article_635.pdf
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WAVE1 and WAVE2 have distinct and overlapping roles in controlling actin assembly at the leading edge.

Molecular Biology Of The Cell
Tang, Qing Q; Schaks, Matthias M; Koundinya, Neha N; Yang, Changsong C; Pollard, Luther W LW; Svitkina, Tatyana M TM; Rottner, Klemens K; Goode, Bruce L BL
Publication Date: 2020-09-15

Variant appearance in text: CCD: Q61L
PubMed Link: 32697617
Variant Present in the following documents:
  • Main text
  • mbc-31-2168.pdf
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An intestinal zinc sensor regulates food intake and developmental growth.

Nature
Redhai, Siamak S; Pilgrim, Clare C; Gaspar, Pedro P; Giesen, Lena van LV; Lopes, Tatiana T; Riabinina, Olena O; Grenier, Théodore T; Milona, Alexandra A; Chanana, Bhavna B; Swadling, Jacob B JB; Wang, Yi-Fang YF; Dahalan, Farah F; Yuan, Michaela M; Wilsch-Brauninger, Michaela M; Lin, Wei-Hsiang WH; Dennison, Nathan N; Capriotti, Paolo P; Lawniczak, Mara K N MKN; Baines, Richard A RA; Warnecke, Tobias T; Windbichler, Nikolai N; Leulier, Francois F; Bellono, Nicholas W NW; Miguel-Aliaga, Irene I
Publication Date: 2020-04

Variant appearance in text: CCD: Q61L
PubMed Link: 32269334
Variant Present in the following documents:
  • Main text
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Vav2 lacks Ca2+ entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42.

Journal Of Cell Science
Fray, Michael A MA; Charpentier, John C JC; Sylvain, Nicholas R NR; Seminario, Maria-Cristina MC; Bunnell, Stephen C SC
Publication Date: 2020-03-13

Variant appearance in text: CCD: Q61L
PubMed Link: 31974114
Variant Present in the following documents:
  • Main text
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The RhoGAP SPV-1 regulates calcium signaling to control the contractility of the Caenorhabditis elegans spermatheca during embryo transits.

Molecular Biology Of The Cell
Bouffard, Jeff J; Cecchetelli, Alyssa D AD; Clifford, Coleman C; Sethi, Kriti K; Zaidel-Bar, Ronen R; Cram, Erin J EJ
Publication Date: 2019-03-21

Variant appearance in text: CCD: Q61L
PubMed Link: 30726159
Variant Present in the following documents:
  • Main text
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Direct multiplex imaging and optogenetics of Rho GTPases enabled by near-infrared FRET.

Nature Chemical Biology
Shcherbakova, Daria M DM; Cox Cammer, Natasha N; Huisman, Tsipora M TM; Verkhusha, Vladislav V VV; Hodgson, Louis L
Publication Date: 2018-06

Variant appearance in text: CCD: Q61L
PubMed Link: 29686359
Variant Present in the following documents:
  • Main text
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MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.

Scientific Reports
Vodicska, Barbara B; Cerikan, Berati B; Schiebel, Elmar E; Hoffmann, Ingrid I
Publication Date: 2018-04-20

Variant appearance in text: CCD: Q61L
PubMed Link: 29679050
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_24682.pdf
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Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo.

Developmental Biology
Sepúlveda-Ramírez, Silvia P SP; Toledo-Jacobo, Leslie L; Henson, John H JH; Shuster, Charles B CB
Publication Date: 2018-05-15

Variant appearance in text: CCD: Q61L
PubMed Link: 29555242
Variant Present in the following documents:
  • Main text
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Local control of intracellular microtubule dynamics by EB1 photodissociation.

Nature Cell Biology
van Haren, Jeffrey J; Charafeddine, Rabab A RA; Ettinger, Andreas A; Wang, Hui H; Hahn, Klaus M KM; Wittmann, Torsten T
Publication Date: 2018-03

Variant appearance in text: CCD: Q61L
PubMed Link: 29379139
Variant Present in the following documents:
  • Main text
  • nihms927629.pdf
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A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.

Cell
Newby, Gregory A GA; Kiriakov, Szilvia S; Hallacli, Erinc E; Kayatekin, Can C; Tsvetkov, Peter P; Mancuso, Christopher P CP; Bonner, J Maeve JM; Hesse, William R WR; Chakrabortee, Sohini S; Manogaran, Anita L AL; Liebman, Susan W SW; Lindquist, Susan S; Khalil, Ahmad S AS
Publication Date: 2017-11-02

Variant appearance in text: CCD: Q61L
PubMed Link: 29056345
Variant Present in the following documents:
  • Main text
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Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.

Molecular Biology Of The Cell
Rosenberg, Brian J BJ; Gil-Henn, Hava H; Mader, Christopher C CC; Halo, Tiffany T; Yin, Taofei T; Condeelis, John J; Machida, Kazuya K; Wu, Yi I YI; Koleske, Anthony J AJ
Publication Date: 2017-05-15

Variant appearance in text: CCD: Q61L
PubMed Link: 28356423
Variant Present in the following documents:
  • Main text
  • 1347.pdf
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Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.

Arteriosclerosis, Thrombosis, And Vascular Biology
Ceneri, Nicolle N; Zhao, Lina L; Young, Bryan D BD; Healy, Abigail A; Coskun, Suleyman S; Vasavada, Hema H; Yarovinsky, Timur O TO; Ike, Kenneth K; Pardi, Ruggero R; Qin, Lingfen L; Qin, Li L; Tellides, George G; Hirschi, Karen K; Meadows, Judith J; Soufer, Robert R; Chun, Hyung J HJ; Sadeghi, Mehran M MM; Bender, Jeffrey R JR; Morrison, Alan R AR
Publication Date: 2017-02

Variant appearance in text: RUNX2: Q61L
PubMed Link: 27834690
Variant Present in the following documents:
  • Main text
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Automated analysis of filopodial length and spatially resolved protein concentration via adaptive shape tracking.

Molecular Biology Of The Cell
Saha, Tanumoy T; Rathmann, Isabel I; Viplav, Abhiyan A; Panzade, Sadhana S; Begemann, Isabell I; Rasch, Christiane C; Klingauf, Jürgen J; Matis, Maja M; Galic, Milos M
Publication Date: 2016-11-07

Variant appearance in text: CCD: Q61L
PubMed Link: 27535428
Variant Present in the following documents:
  • Main text
  • 3616.pdf
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The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.

Structure (London, England : 1993)
LeCour, Louis L; Boyapati, Vamsi K VK; Liu, Jing J; Li, Zhigang Z; Sacks, David B DB; Worthylake, David K DK
Publication Date: 2016-09-06

Variant appearance in text: CCD: Q61L
PubMed Link: 27524202
Variant Present in the following documents:
  • Main text
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A role for activated Cdc42 in glioblastoma multiforme invasion.

Oncotarget
Okura, Hidehiro H; Golbourn, Brian J BJ; Shahzad, Uswa U; Agnihotri, Sameer S; Sabha, Nesrin N; Krieger, Jonathan R JR; Figueiredo, Carlyn A CA; Chalil, Alan A; Landon-Brace, Natalie N; Riemenschneider, Alexandra A; Arai, Hajime H; Smith, Christian A CA; Xu, Songli S; Kaluz, Stefan S; Marcus, Adam I AI; Van Meir, Erwin G EG; Rutka, James T JT
Publication Date: 2016-08-30

Variant appearance in text: CCD: Q61L
PubMed Link: 27486972
Variant Present in the following documents:
  • Main text
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The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion.

Oncotarget
Maine, Erin A EA; Westcott, Jill M JM; Prechtl, Amanda M AM; Dang, Tuyen T TT; Whitehurst, Angelique W AW; Pearson, Gray W GW
Publication Date: 2016-03-22

Variant appearance in text: CCD: Q61L
PubMed Link: 26895102
Variant Present in the following documents:
  • Main text
  • oncotarget-07-14708.pdf
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Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1.

Journal Of Cell Science
Francis, Monika K MK; Holst, Mikkel R MR; Vidal-Quadras, Maite M; Henriksson, Sara S; Santarella-Mellwig, Rachel R; Sandblad, Linda L; Lundmark, Richard R
Publication Date: 2015-11-15

Variant appearance in text: CCD: Q61L
PubMed Link: 26446261
Variant Present in the following documents:
  • Main text
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Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.

Nature Cell Biology
Lomakin, Alexis J AJ; Lee, Kun-Chun KC; Han, Sangyoon J SJ; Bui, Duyen A DA; Davidson, Michael M; Mogilner, Alex A; Danuser, Gaudenz G
Publication Date: 2015-11

Variant appearance in text: CCD: Q61L
PubMed Link: 26414403
Variant Present in the following documents:
  • Main text
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Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Delorme-Walker, Violaine V; Seo, Ji-Yeon JY; Gohla, Antje A; Fowler, Bruce B; Bohl, Ben B; DerMardirossian, Céline C
Publication Date: 2015-09-15

Variant appearance in text: CCD: Q61L
PubMed Link: 26324884
Variant Present in the following documents:
  • Main text
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TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility.

Plos One
Cáceres, Mónica M; Ortiz, Liliana L; Recabarren, Tatiana T; Romero, Anibal A; Colombo, Alicia A; Leiva-Salcedo, Elías E; Varela, Diego D; Rivas, José J; Silva, Ian I; Morales, Diego D; Campusano, Camilo C; Almarza, Oscar O; Simon, Felipe F; Toledo, Hector H; Park, Kang-Sik KS; Trimmer, James S JS; Cerda, Oscar O
Publication Date: 2015

Variant appearance in text: CCD: Q61L
PubMed Link: 26110647
Variant Present in the following documents:
  • Main text
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The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.

Nature Communications
Kühn, Sonja S; Erdmann, Constanze C; Kage, Frieda F; Block, Jennifer J; Schwenkmezger, Lisa L; Steffen, Anika A; Rottner, Klemens K; Geyer, Matthias M
Publication Date: 2015-05-12

Variant appearance in text: CCD: Q61L
PubMed Link: 25963737
Variant Present in the following documents:
  • Main text
  • ncomms8088.pdf
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Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity.

The Journal Of Biological Chemistry
Sato, Tatsuhiro T; Akasu, Hitomi H; Shimono, Wataru W; Matsu, Chisa C; Fujiwara, Yuki Y; Shibagaki, Yoshio Y; Heard, Jeffrey J JJ; Tamanoi, Fuyuhiko F; Hattori, Seisuke S
Publication Date: 2015-01-09

Variant appearance in text: CCD: Q61L
PubMed Link: 25422319
Variant Present in the following documents:
  • Main text
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A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.

Nature Cell Biology
Moshfegh, Yasmin Y; Bravo-Cordero, Jose Javier JJ; Miskolci, Veronika V; Condeelis, John J; Hodgson, Louis L
Publication Date: 2014-06

Variant appearance in text: CCD: Q61L
PubMed Link: 24859002
Variant Present in the following documents:
  • Main text
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An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.

The Journal Of Cell Biology
Tata, Aleksandra A; Stoppel, David C DC; Hong, Shangyu S; Ben-Zvi, Ayal A; Xie, Tiao T; Gu, Chenghua C
Publication Date: 2014-05-26

Variant appearance in text: CCD: Q61L
PubMed Link: 24841563
Variant Present in the following documents:
  • JCB_201309004.pdf
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A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging.

Plos One
Hanna, Samer S; Miskolci, Veronika V; Cox, Dianne D; Hodgson, Louis L
Publication Date: 2014

Variant appearance in text: CCD: Q61L
PubMed Link: 24798463
Variant Present in the following documents:
  • Main text
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Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).

The Journal Of Biological Chemistry
Mazhab-Jafari, Mohammad T MT; Marshall, Christopher B CB; Ho, Jason J; Ishiyama, Noboru N; Stambolic, Vuk V; Ikura, Mitsuhiko M
Publication Date: 2014-05-02

Variant appearance in text: CCD: Q61L
PubMed Link: 24648513
Variant Present in the following documents:
  • Main text
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Exo70 generates membrane curvature for morphogenesis and cell migration.

Developmental Cell
Zhao, Yuting Y; Liu, Jianglan J; Yang, Changsong C; Capraro, Benjamin R BR; Baumgart, Tobias T; Bradley, Ryan P RP; Ramakrishnan, N N; Xu, Xiaowei X; Radhakrishnan, Ravi R; Svitkina, Tatyana T; Guo, Wei W
Publication Date: 2013-08-12

Variant appearance in text: CCD: Q61L
PubMed Link: 23948253
Variant Present in the following documents:
  • Main text
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Bud4 mediates the cell-type-specific assembly of the axial landmark in budding yeast.

Journal Of Cell Science
Kang, Pil Jung PJ; Angerman, Elizabeth E; Jung, Chan-Hun CH; Park, Hay-Oak HO
Publication Date: 2012-08-15

Variant appearance in text: CCD: Q61L
PubMed Link: 22553209
Variant Present in the following documents:
  • Main text
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Involvement of Beclin 1 in engulfment of apoptotic cells.

The Journal Of Biological Chemistry
Konishi, Akimitsu A; Arakawa, Satoko S; Yue, Zhenyu Z; Shimizu, Shigeomi S
Publication Date: 2012-04-20

Variant appearance in text: CCD: Q61L
PubMed Link: 22393062
Variant Present in the following documents:
  • Main text
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Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization.

Science Signaling
Wang, Yuxiao Y; He, Huawei H; Srivastava, Nishi N; Vikarunnessa, Sheikh S; Chen, Yong-bin YB; Jiang, Jin J; Cowan, Christopher W CW; Zhang, Xuewu X
Publication Date: 2012-01-17

Variant appearance in text: CCD: Q61L
PubMed Link: 22253263
Variant Present in the following documents:
  • Main text
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A dual binding mode for RhoGTPases in plexin signalling.

Plos Biology
Bell, Christian H CH; Aricescu, A Radu AR; Jones, E Yvonne EY; Siebold, Christian C
Publication Date: 2011-08

Variant appearance in text: CCD: Gln61Leu
PubMed Link: 21912513
Variant Present in the following documents:
  • Main text
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The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.

The Journal Of Biological Chemistry
Kim, Jeong-Yoon JY; Oh, Mi Hee MH; Bernard, Laura P LP; Macara, Ian G IG; Zhang, Huaye H
Publication Date: 2011-10-28

Variant appearance in text: CCD: Q61L
PubMed Link: 21900250
Variant Present in the following documents:
  • Main text
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Enterohemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells.

American Journal Of Physiology. Cell Physiology
Lukyanenko, Valeriy V; Malyukova, Irina I; Hubbard, Ann A; Delannoy, Michael M; Boedeker, Edgar E; Zhu, Chengru C; Cebotaru, Liudmila L; Kovbasnjuk, Olga O
Publication Date: 2011-11

Variant appearance in text: CCD: Q61L
PubMed Link: 21832249
Variant Present in the following documents:
  • Main text
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Cla4 kinase triggers destruction of the Rac1-GEF Cdc24 during polarized growth in Ustilago maydis.

Molecular Biology Of The Cell
Frieser, Sonja Helene SH; Hlubek, Andrea A; Sandrock, Björn B; Bölker, Michael M
Publication Date: 2011-09

Variant appearance in text: CCD: Q61L
PubMed Link: 21757543
Variant Present in the following documents:
  • Main text
  • 3253.pdf
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Structure and control of the actin regulatory WAVE complex.

Nature
Chen, Zhucheng Z; Borek, Dominika D; Padrick, Shae B SB; Gomez, Timothy S TS; Metlagel, Zoltan Z; Ismail, Ayman M AM; Umetani, Junko J; Billadeau, Daniel D DD; Otwinowski, Zbyszek Z; Rosen, Michael K MK
Publication Date: 2010-11-25

Variant appearance in text: CCD: Q61L
PubMed Link: 21107423
Variant Present in the following documents:
  • NIHMS248952-supplement-supplement_1.pdf
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GTPase activity plays a key role in the pathobiology of LRRK2.

Plos Genetics
Xiong, Yulan Y; Coombes, Candice E CE; Kilaru, Austin A; Li, Xiaojie X; Gitler, Aaron D AD; Bowers, William J WJ; Dawson, Valina L VL; Dawson, Ted M TM; Moore, Darren J DJ
Publication Date: 2010-04-08

Variant appearance in text: CCD: Q61L
PubMed Link: 20386743
Variant Present in the following documents:
  • Main text
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Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators.

Oncogene
Wang, S E SE; Yu, Y Y; Criswell, T L TL; Debusk, L M LM; Lin, P C PC; Zent, R R; Johnson, D H DH; Ren, X X; Arteaga, C L CL
Publication Date: 2010-06-10

Variant appearance in text: CCD: Q61L
PubMed Link: 20383197
Variant Present in the following documents:
  • Main text
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The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.

Traffic (Copenhagen, Denmark)
Fang, Zhiyou Z; Takizawa, Norio N; Wilson, Korey A KA; Smith, Tara C TC; Delprato, Anna A; Davidson, Michael W MW; Lambright, David G DG; Luna, Elizabeth J EJ
Publication Date: 2010-06

Variant appearance in text: CCD: Q61L
PubMed Link: 20331534
Variant Present in the following documents:
  • Main text
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Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L).

Cancer Biology & Therapy
Yang, Dianer D; Wang, Man-Tzu MT; Tang, Yong Y; Chen, Yakun Y; Jiang, Hongmei H; Jones, Torrie T TT; Rao, Krishna K; Brewer, Gregory J GJ; Singh, Keshav K KK; Nie, Daotai D
Publication Date: 2010-01

Variant appearance in text: CCD: Q61L
PubMed Link: 19923925
Variant Present in the following documents:
  • Main text
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Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.

Science Signaling
Gianni, Davide D; Diaz, Begoña B; Taulet, Nicolas N; Fowler, Bruce B; Courtneidge, Sara A SA; Bokoch, Gary M GM
Publication Date: 2009-09-15

Variant appearance in text: CCD: Q61L
PubMed Link: 19755710
Variant Present in the following documents:
  • Main text
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Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

Cell Communication And Signaling : Ccs
Putnam, Andrew J AJ; Schulz, Veronique V VV; Freiter, Eric M EM; Bill, Heather M HM; Miranti, Cindy K CK
Publication Date: 2009-04-28

Variant appearance in text: CCD: Q61L
PubMed Link: 19400942
Variant Present in the following documents:
  • Main text
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Transport of mannose-6-phosphate receptors from the trans-Golgi network to endosomes requires Rab31.

Experimental Cell Research
Rodriguez-Gabin, A G AG; Yin, X X; Si, Q Q; Larocca, J N JN
Publication Date: 2009-08-01

Variant appearance in text: CCD: Q61L
PubMed Link: 19345684
Variant Present in the following documents:
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Coordination of cytokinesis and cell separation by endosomal targeting of a Cdc42-specific guanine nucleotide exchange factor in Ustilago maydis.

Molecular Biology Of The Cell
Schink, Kay Oliver KO; Bölker, Michael M
Publication Date: 2009-02

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PubMed Link: 19073889
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Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.

The Journal Of Biological Chemistry
Ruusala, Aino A; Pawson, Tony T; Heldin, Carl-Henrik CH; Aspenström, Pontus P
Publication Date: 2008-10-31

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PubMed Link: 18765673
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The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.

The Journal Of Cell Biology
Sakurai-Yageta, Mika M; Recchi, Chiara C; Le Dez, Gaëlle G; Sibarita, Jean-Baptiste JB; Daviet, Laurent L; Camonis, Jacques J; D'Souza-Schorey, Crislyn C; Chavrier, Philippe P
Publication Date: 2008-06-16

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PubMed Link: 18541705
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Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42.

The Journal Of Biological Chemistry
Phillips, Matthew J MJ; Calero, Guillermo G; Chan, Britton B; Ramachandran, Sekar S; Cerione, Richard A RA
Publication Date: 2008-05-16

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PubMed Link: 18348980
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