Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.
Chemical Science
Noresson, A-L AL; Aurelius, O O; Öberg, C T CT; Engström, O O; Sundin, A P AP; Håkansson, M M; Stenström, O O; Akke, M M; Logan, D T DT; Leffler, H H; Nilsson, U J UJ
The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry
Nguyen, Tinh T TT; Fedorov, Alexander A AA; Williams, Lakenya L; Fedorov, Elena V EV; Li, Yingchun Y; Xu, Chengfu C; Almo, Steven C SC; Raushel, Frank M FM