RUNX2 c.557G>A ;(p.R186K)

Variant ID: 6-45399733-G-A

NM_001024630.3(RUNX2):c.557G>A;(p.R186K)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

Chemical Science
Noresson, A-L AL; Aurelius, O O; Öberg, C T CT; Engström, O O; Sundin, A P AP; Håkansson, M M; Stenström, O O; Akke, M M; Logan, D T DT; Leffler, H H; Nilsson, U J UJ
Publication Date: 2018-01-28

Variant appearance in text: CCD: R186K
PubMed Link: 29675148
Variant Present in the following documents:
  • SC-009-C7SC04749E-s001.pdf
View BVdb publication page



The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.

Biochemistry
Nguyen, Tinh T TT; Fedorov, Alexander A AA; Williams, Lakenya L; Fedorov, Elena V EV; Li, Yingchun Y; Xu, Chengfu C; Almo, Steven C SC; Raushel, Frank M FM
Publication Date: 2009-09-22

Variant appearance in text: CCD: R186K
PubMed Link: 19678710
Variant Present in the following documents:
  • Main text
View BVdb publication page