Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
The Journal Of Pathology
Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I
Wong, Chi C CC; Martincorena, Inigo I; Rust, Alistair G AG; Rashid, Mamunur M; Alifrangis, Constantine C; Alexandrov, Ludmil B LB; Tiffen, Jessamy C JC; Kober, Christina C; , ; Green, Anthony R AR; Massie, Charles E CE; Nangalia, Jyoti J; Lempidaki, Stella S; Döhner, Hartmut H; Döhner, Konstanze K; Bray, Sarah J SJ; McDermott, Ultan U; Papaemmanuil, Elli E; Campbell, Peter J PJ; Adams, David J DJ