Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Molecular Cancer
Cho, Jeonghee J; Bass, Adam J AJ; Lawrence, Michael S MS; Cibulskis, Kristian K; Cho, Ahye A; Lee, Shi-Nai SN; Yamauchi, Mai M; Wagle, Nikhil N; Pochanard, Panisa P; Kim, Nayoung N; Park, Angela Kj AK; Won, Jonghwa J; Hur, Hyung-Suk HS; Greulich, Heidi H; Ogino, Shuji S; Sougnez, Carrie C; Voet, Douglas D; Tabernero, Josep J; Jimenez, Jose J; Baselga, Jose J; Gabriel, Stacey B SB; Lander, Eric S ES; Getz, Gad G; Eck, Michael J MJ; Park, Woong-Yang WY; Meyerson, Matthew M
Publication Date: 2014-06-04
Variant appearance in text: THSD7A: 2542T>G; W848G