Publications:

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Murine and human CFTR exhibit different sensitivities to CFTR potentiators.

American Journal Of Physiology. Lung Cellular And Molecular Physiology

Cui, Guiying G; McCarty, Nael A NA

Publication Date: 2015-10-01

Variant appearance in text: CFTR: R334A

PubMed Link: 26209275

Variant Present in the following documents:

• Main text

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Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.

The Journal Of General Physiology

Cui, Guiying G; Rahman, Kazi S KS; Infield, Daniel T DT; Kuang, Christopher C; Prince, Chengyu Z CZ; McCarty, Nael A NA

Publication Date: 2014-08

Variant appearance in text: CFTR: R334A

PubMed Link: 25024266

Variant Present in the following documents:

• Main text
• JGP_201311122.pdf

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CFTR: a cysteine at position 338 in TM6 senses a positive electrostatic potential in the pore.

Biophysical Journal

Liu, Xuehong X; Zhang, Zhi-Ren ZR; Fuller, Matthew D MD; Billingsley, Joshua J; McCarty, Nael A NA; Dawson, David C DC

Publication Date: 2004-12

Variant appearance in text: CFTR: R334A

PubMed Link: 15361410

Variant Present in the following documents:

• Main text

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Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore.

The Journal Of Physiology

Gong, Xiandi X; Linsdell, Paul P

Publication Date: 2003-06-01

Variant appearance in text: CFTR: R334A

PubMed Link: 12679372

Variant Present in the following documents:

• Main text

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Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore.

The Journal Of Physiology

Gong, Xiandi X; Burbridge, Susan M SM; Cowley, Elizabeth A EA; Linsdell, Paul P

Publication Date: 2002-04-01

Variant appearance in text: CFTR: R334A

PubMed Link: 11927667

Variant Present in the following documents:

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CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction.

The Journal Of General Physiology

Smith, S S SS; Liu, X X; Zhang, Z R ZR; Sun, F F; Kriewall, T E TE; McCarty, N A NA; Dawson, D C DC

Publication Date: 2001-10

Variant appearance in text: CFTR: R334A

PubMed Link: 11585852

Variant Present in the following documents:

• Main text
• 8480.pdf

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