Acute Pancreatitis in a Previously Exocrine Pancreatic Insufficient Cystic Fibrosis Patient Who Had Improved Pancreatic Function After Being Treated With Lumacaftor/Ivacaftor.
Jpgn Reports
Redman, Alexander W AW; Yoo, Michelle M; Freswick, Peter P; Thompson, Karen K
Critical role of down-regulated in adenoma bicarbonate transporter in linaclotide stimulated intestinal bicarbonate secretion.
Biorxiv : The Preprint Server For Biology
Sarthi, Jessica B JB; Trumbull, Annie M AM; Abazari, Shayda M SM; van Unen, Vincent V; Chan, Joshua E JE; Joo, Nam Soo NS; Jiang, Yanfen Y; Kuo, Calvin J CJ; Sellers, Zachary M ZM
Individualized approach to elexacaftor/tezacaftor/ivacaftor dosing in cystic fibrosis, in response to self-reported anxiety and neurocognitive adverse events: A case series.
Frontiers In Pharmacology
Ibrahim, Hisham H; Danish, Hammad H; Morrissey, David D; Deasy, Kevin F KF; McCarthy, Mairead M; Dorgan, James J; Fleming, Claire C; Howlett, Ciara C; Twohig, Sarah S; Vagg, Tamara T; Murphy, Desmond M DM; Maher, Michael M; Plant, Barry J BJ
ROCK STUDY in CF: sustained anti-inflammatory effects of lumacaftor-ivacaftor in sputum and peripheral blood samples of adult patients with cystic fibrosis-an observational study.
Bmj Open Respiratory Research
Arooj, Parniya P; Morrissy, David V DV; McCarthy, Yvonne Y; Vagg, Tamara T; McCarthy, Mairead M; Fleming, Claire C; Daly, Mary M; Eustace, Joseph A JA; Murphy, Desmond M DM; Plant, B J BJ
Long-term effects of lumacaftor/ivacaftor on paranasal sinus abnormalities in children with cystic fibrosis detected with magnetic resonance imaging.
Frontiers In Pharmacology
Wucherpfennig, Lena L; Wuennemann, Felix F; Eichinger, Monika M; Seitz, Angelika A; Baumann, Ingo I; Stahl, Mirjam M; Graeber, Simon Y SY; Zhao, Shengkai S; Chung, Jaehi J; Schenk, Jens-Peter JP; Alrajab, Abdulsattar A; Kauczor, Hans-Ulrich HU; Mall, Marcus A MA; Sommerburg, Olaf O; Wielpütz, Mark O MO
Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis.
Life Science Alliance
Birimberg-Schwartz, Liron L; Ip, Wan W; Bartlett, Claire C; Avolio, Julie J; Vonk, Annelotte M AM; Gunawardena, Tarini T; Du, Kai K; Esmaeili, Mohsen M; Beekman, Jeffrey M JM; Rommens, Johanna J; Strug, Lisa L; Bear, Christine E CE; Moraes, Theo J TJ; Gonska, Tanja T
The synthetic aminoglycoside ELX-02 induces readthrough of G550X-CFTR producing super-functional protein that can be further enhanced by CFTR modulators.
American Journal Of Physiology. Lung Cellular And Molecular Physiology
Chen, Jianguo J; Thrasher, Kari K; Fu, Lianwu L; Wang, Wei W; Aghamohammadzadeh, Soheil S; Wen, Hui H; Tang, Liping L; Keeling, Kim M KM; Falk Libby, Emily E; Bedwell, David M DM; Rowe, Steven M SM
Magnetic resonance imaging detects onset and association with lung disease severity of bronchial artery dilatation in cystic fibrosis.
Erj Open Research
Leutz-Schmidt, Patricia P; Optazaite, Daiva-Elzbieta DE; Sommerburg, Olaf O; Eichinger, Monika M; Wege, Sabine S; Steinke, Eva E; Graeber, Simon Y SY; Puderbach, Michael U MU; Schenk, Jens-Peter JP; Alrajab, Abdulsattar A; Triphan, Simon M F SMF; Kauczor, Hans-Ulrich HU; Stahl, Mirjam M; Mall, Marcus A MA; Wielpütz, Mark O MO
Immunoreactive Trypsinogen in Infants Born to Women with Cystic Fibrosis Taking Elexacaftor-Tezacaftor-Ivacaftor.
International Journal Of Neonatal Screening
Patel, Payal P; Yeley, Jana J; Brown, Cynthia C; Wesson, Melissa M; Lesko, Barbara G BG; Slaven, James E JE; Chmiel, James F JF; Jain, Raksha R; Sanders, Don B DB
Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization.
Microbiology Spectrum
Enaud, Raphael R; Lussac-Sorton, Florian F; Charpentier, Elena E; Velo-Suárez, Lourdes L; Guiraud, Jennifer J; Bui, Stéphanie S; Fayon, Michael M; Schaeverbeke, Thierry T; Nikolski, Macha M; , ; Burgel, Pierre-Régis PR; Héry-Arnaud, Geneviève G; Delhaes, Laurence L
Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs.
Molecular Therapy. Methods & Clinical Development
Tang, Yinghua Y; Fakhari, Shahab S; Huntemann, Eric D ED; Feng, Zehua Z; Wu, Peipei P; Feng, William Y WY; Lei, Junying J; Yuan, Feng F; Excoffon, Katherine J KJ; Wang, Kai K; Limberis, Maria P MP; Kolbeck, Roland R; Yan, Ziying Z; Engelhardt, John F JF
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: CFTR: 1652G>A; Gly551Asp
Pharmacogenetic actionability and medication prescribing in people with cystic fibrosis.
Clinical And Translational Science
Anderson, Justin D JD; Davis, Brittney H BH; Giang, Gracie G; Jones, April A; Lee, Cameron R CR; Parker, Kennedy K; Searcy, Heather H; Benner, Kim K; Limdi, Nita A NA; Guimbellot, Jennifer S JS
Effects of CFTR-modulator triple therapy on sinunasal symptoms in children and adults with cystic fibrosis.
European Archives Of Oto-Rhino-Laryngology : Official Journal Of The European Federation Of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With The German Society For Oto-Rhino-Laryngology - Head And Neck Surgery
Bode, Sebastian F N SFN; Rapp, Hannes H; Lienert, Nadine N; Appel, Heike H; Fabricius, Dorit D
Corcoran, Timothy E TE; Bertrand, Carol A CA; Myerburg, Michael M MM; Weiner, Daniel J DJ; Frizzell, Sheila A SA; Li, Anna A; Agostini, Brittani B; Parker, Robert S RS; Shapiro, Monica E ME; Muthukrishnan, Ashok A; Hages, Nicholas D ND; Mulhern, Brian P BP; Pilewski, Joseph M JM
The CFHealthHub Learning Health System: Using Real-Time Adherence Data to Support a Community of Practice to Deliver Continuous Improvement in an Archetypal Long-Term Condition.