CFTR c.1921_1922delinsGC ;(p.S641A)

Variant ID: 7-117232142-AG-GC

NM_000492.3(CFTR):c.1921_1922delinsGC;(p.S641A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Changes in the R-region interactions depend on phosphorylation and contribute to PKA and PKC regulation of the cystic fibrosis transmembrane conductance regulator chloride channel.

Faseb Bioadvances
Poroca, Diogo R DR; Amer, Noha N; Li, Audrey A; Hanrahan, John W JW; Chappe, Valerie M VM
Publication Date: 2020-01

Variant appearance in text: CFTR: S641A
PubMed Link: 32123855
Variant Present in the following documents:
  • Main text
  • FBA2-2-33.pdf
View BVdb publication page



Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane.

Molecular Biology Of The Cell
Apaja, Pirjo M PM; Foo, Brian B; Okiyoneda, Tsukasa T; Valinsky, William C WC; Barriere, Herve H; Atanasiu, Roxana R; Ficker, Eckhard E; Lukacs, Gergely L GL; Shrier, Alvin A
Publication Date: 2013-12

Variant appearance in text: CFTR: S641A
PubMed Link: 24152733
Variant Present in the following documents:
  • Main text
  • 3787.pdf
  • supp_E13-07-0417v1_CombinedSupMats.pdf
View BVdb publication page



Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).

The Journal Of Biological Chemistry
Billet, Arnaud A; Luo, Yishan Y; Balghi, Haouaria H; Hanrahan, John W JW
Publication Date: 2013-07-26

Variant appearance in text: CFTR: S641A
PubMed Link: 23760269
Variant Present in the following documents:
  • Main text
View BVdb publication page



Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Chappe, Valerie V; Hinkson, Deborah A DA; Howell, L Daniel LD; Evagelidis, Alexandra A; Liao, Jie J; Chang, Xiu-Bao XB; Riordan, John R JR; Hanrahan, John W JW
Publication Date: 2004-01-06

Variant appearance in text: CFTR: S641A
PubMed Link: 14695900
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.

The Journal Of Physiology
Chappe, V V; Hinkson, D A DA; Zhu, T T; Chang, X-B XB; Riordan, J R JR; Hanrahan, J W JW
Publication Date: 2003-04-01

Variant appearance in text: CFTR: S641A
PubMed Link: 12588899
Variant Present in the following documents:
  • Main text
View BVdb publication page