Publications:

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Protein kinase A phosphorylation potentiates cystic fibrosis transmembrane conductance regulator gating by relieving autoinhibition on the stimulatory C terminus of the regulatory domain.

The Journal Of Biological Chemistry

Chen, Jeng-Haur JH

Publication Date: 2020-04-03

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PubMed Link: 32102849

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Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity.

Plos One

Malik, Firhan A FA; Meissner, Anja A; Semenkov, Illya I; Molinski, Steven S; Pasyk, Stan S; Ahmadi, Saumel S; Bui, Hai H HH; Bear, Christine E CE; Lidington, Darcy D; Bolz, Steffen-Sebastian SS

Publication Date: 2015

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PubMed Link: 26079370

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LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells.

The Journal Of Biological Chemistry

Luz, Simão S; Cihil, Kristine M KM; Brautigan, David L DL; Amaral, Margarida D MD; Farinha, Carlos M CM; Swiatecka-Urban, Agnieszka A

Publication Date: 2014-05-23

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PubMed Link: 24727471

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• zbc15080.pdf

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Structural models of CFTR-AMPK and CFTR-PKA interactions: R-domain flexibility is a key factor in CFTR regulation.

Journal Of Molecular Modeling

Siwiak, Marian M; Edelman, Aleksander A; Zielenkiewicz, Piotr P

Publication Date: 2012-01

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PubMed Link: 21455600

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• 894_2011_Article_1029.pdf

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The inhibition mechanism of non-phosphorylated Ser768 in the regulatory domain of cystic fibrosis transmembrane conductance regulator.

The Journal Of Biological Chemistry

Wang, Guangyu G

Publication Date: 2011-01-21

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PubMed Link: 21059651

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State-dependent regulation of cystic fibrosis transmembrane conductance regulator (CFTR) gating by a high affinity Fe3+ bridge between the regulatory domain and cytoplasmic loop 3.

The Journal Of Biological Chemistry

Wang, Guangyu G

Publication Date: 2010-12-24

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PubMed Link: 20952391

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Mechanistic insight into control of CFTR by AMPK.

The Journal Of Biological Chemistry

Kongsuphol, Patthara P; Cassidy, Diane D; Hieke, Bernhard B; Treharne, Kate J KJ; Schreiber, Rainer R; Mehta, Anil A; Kunzelmann, Karl K

Publication Date: 2009-02-27

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PubMed Link: 19095655

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• 5645.pdf

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Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

The Journal Of General Physiology

Csanády, László L; Seto-Young, Donna D; Chan, Kim W KW; Cenciarelli, Cristina C; Angel, Benjamin B BB; Qin, Jun J; McLachlin, Derek T DT; Krutchinsky, Andrew N AN; Chait, Brian T BT; Nairn, Angus C AC; Gadsby, David C DC

Publication Date: 2005-02

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PubMed Link: 15657296

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• 200409076.pdf

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