BRAF c.1800G>C ;(p.V600=)

Variant ID: 7-140453135-C-G

NM_004333.4(BRAF):c.1800G>C;(p.V600=)

This variant was identified in 27 publications

View GRCh38 version.




Publications:


Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: V600V
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: BRAF: V600V
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology
Georgoulias, George G; Zaravinos, Apostolos A
Publication Date: 2022

Variant appearance in text: BRAF: V600V
PubMed Link: 36389735
Variant Present in the following documents:
  • Table_7.xlsx, sheet 8
View BVdb publication page



The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

Cancer Research
Sjöström, Martin M; Zhao, Shuang G SG; Levy, Samuel S; Zhang, Meng M; Ning, Yuhong Y; Shrestha, Raunak R; Lundberg, Arian A; Herberts, Cameron C; Foye, Adam A; Aggarwal, Rahul R; Hua, Junjie T JT; Li, Haolong H; Bergamaschi, Anna A; Maurice-Dror, Corinne C; Maheshwari, Ashutosh A; Chen, Sujun S; Ng, Sarah W S SWS; Ye, Wenbin W; Petricca, Jessica J; Fraser, Michael M; Chesner, Lisa L; Perry, Marc D MD; Moreno-Rodriguez, Thaidy T; Chen, William S WS; Alumkal, Joshi J JJ; Chou, Jonathan J; Morgans, Alicia K AK; Beer, Tomasz M TM; Thomas, George V GV; Gleave, Martin M; Lloyd, Paul P; Phillips, Tierney T; McCarthy, Erin E; Haffner, Michael C MC; Zoubeidi, Amina A; Annala, Matti M; Reiter, Robert E RE; Rettig, Matthew B MB; Witte, Owen N ON; Fong, Lawrence L; Bose, Rohit R; Huang, Franklin W FW; Luo, Jianhua J; Bjartell, Anders A; Lang, Joshua M JM; Mahajan, Nupam P NP; Lara, Primo N PN; Evans, Christopher P CP; Tran, Phuoc T PT; Posadas, Edwin M EM; He, Chuan C; Cui, Xiao-Long XL; Huang, Jiaoti J; Zwart, Wilbert W; Gilbert, Luke A LA; Maher, Christopher A CA; Boutros, Paul C PC; Chi, Kim N KN; Ashworth, Alan A; Small, Eric J EJ; He, Housheng H HH; Wyatt, Alexander W AW; Quigley, David A DA; Feng, Felix Y FY
Publication Date: 2022-11-02

Variant appearance in text: BRAF: V600V
PubMed Link: 36251389
Variant Present in the following documents:
  • can-22-1123_supplementary_table_3_suppst3.xlsx, sheet 1
View BVdb publication page



Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.

Pigment Cell & Melanoma Research
Christodoulou, Eirini E; Rashid, Mamunur M; Pacini, Clare C; Droop, Alastair A; Robertson, Holly H; Groningen, Tim van TV; Teunisse, Amina F A S AFAS; Iorio, Francesco F; Jochemsen, Aart G AG; Adams, David J DJ; Doorn, Remco van RV
Publication Date: 2021-01

Variant appearance in text: BRAF: V600V
PubMed Link: 32767816
Variant Present in the following documents:
  • PCMR-34-122-s006.xlsx, sheet 1
View BVdb publication page



Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy.

Iscience
Nagasawa, Ikuko I; Koido, Masaru M; Tani, Yuri Y; Tsukahara, Satomi S; Kunimasa, Kazuhiro K; Tomida, Akihiro A
Publication Date: 2020-04-24

Variant appearance in text: BRAF: V600V
PubMed Link: 32283529
Variant Present in the following documents:
  • main.pdf
  • mmc1.pdf
View BVdb publication page



Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology
Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M
Publication Date: 2020-01-07

Variant appearance in text: BRAF: V600V
PubMed Link: 31925297
Variant Present in the following documents:
  • 42003_2019_736_MOESM13_ESM.xlsx, sheet 1
View BVdb publication page



Identification of 12 cancer types through genome deep learning.

Scientific Reports
Sun, Yingshuai Y; Zhu, Sitao S; Ma, Kailong K; Liu, Weiqing W; Yue, Yao Y; Hu, Gang G; Lu, Huifang H; Chen, Wenbin W
Publication Date: 2019-11-21

Variant appearance in text: BRAF: V600V
PubMed Link: 31754222
Variant Present in the following documents:
  • 41598_2019_53989_MOESM4_ESM.xlsx, sheet 11
  • 41598_2019_53989_MOESM4_ESM.xlsx, sheet 10
View BVdb publication page



Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer.

Scientific Reports
D'Oronzo, Stella S; Lovero, Domenica D; Palmirotta, Raffaele R; Stucci, Luigia Stefania LS; Tucci, Marco M; Felici, Claudia C; Cascardi, Eliano E; Giardina, Carmela C; Cafforio, Paola P; Silvestris, Franco F
Publication Date: 2019-11-21

Variant appearance in text: BRAF: V600V
PubMed Link: 31754145
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Robb, Ryan R; Yang, Linlin L; Shen, Changxian C; Wolfe, Adam R AR; Webb, Amy A; Zhang, Xiaoli X; Vedaie, Marall M; Saji, Motoyasu M; Jhiang, Sissy S; Ringel, Matthew D MD; Williams, Terence M TM
Publication Date: 2019-08-01

Variant appearance in text: BRAF: V600V
PubMed Link: 31097454
Variant Present in the following documents:
  • Main text
View BVdb publication page



Systemic Therapy in Metastatic Melanoma.

Federal Practitioner : For The Health Care Professionals Of The Va, Dod, And Phs
Goyal, Gaurav G; Silberstein, Peter T PT
Publication Date: 2015-05

Variant appearance in text: BRAF: V600V
PubMed Link: 30766124
Variant Present in the following documents:
  • Main text
View BVdb publication page



Patient-derived xenograft mouse models: A high fidelity tool for individualized medicine.

Oncology Letters
Xu, Cong C; Li, Xuelu X; Liu, Pixu P; Li, Man M; Luo, Fuwen F
Publication Date: 2019-01

Variant appearance in text: BRAF: V600V
PubMed Link: 30655732
Variant Present in the following documents:
  • Main text
View BVdb publication page



An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Scientific Reports
Collord, Grace G; Tarpey, Patrick P; Kurbatova, Natalja N; Martincorena, Inigo I; Moran, Sebastian S; Castro, Manuel M; Nagy, Tibor T; Bignell, Graham G; Maura, Francesco F; Young, Matthew D MD; Berna, Jorge J; Tubio, Jose M C JMC; McMurran, Chris E CE; Young, Adam M H AMH; Sanders, Mathijs M; Noorani, Imran I; Price, Stephen J SJ; Watts, Colin C; Leipnitz, Elke E; Kirsch, Matthias M; Schackert, Gabriele G; Pearson, Danita D; Devadass, Abel A; Ram, Zvi Z; Collins, V Peter VP; Allinson, Kieren K; Jenkinson, Michael D MD; Zakaria, Rasheed R; Syed, Khaja K; Hanemann, C Oliver CO; Dunn, Jemma J; McDermott, Michael W MW; Kirollos, Ramez W RW; Vassiliou, George S GS; Esteller, Manel M; Behjati, Sam S; Brazma, Alvis A; Santarius, Thomas T; McDermott, Ultan U
Publication Date: 2018-09-10

Variant appearance in text: BRAF: V600V
PubMed Link: 30202034
Variant Present in the following documents:
  • 41598_2018_31659_MOESM2_ESM.xlsx, sheet 30
View BVdb publication page



From word models to executable models of signaling networks using automated assembly.

Molecular Systems Biology
Gyori, Benjamin M BM; Bachman, John A JA; Subramanian, Kartik K; Muhlich, Jeremy L JL; Galescu, Lucian L; Sorger, Peter K PK
Publication Date: 2017-11-24

Variant appearance in text: BRAF: V600=
PubMed Link: 29175850
Variant Present in the following documents:
  • MSB-13-954-s001.pdf
View BVdb publication page



Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Acta Neuropathologica Communications
Salloum, Ralph R; McConechy, Melissa K MK; Mikael, Leonie G LG; Fuller, Christine C; Drissi, Rachid R; DeWire, Mariko M; Nikbakht, Hamid H; De Jay, Nicolas N; Yang, Xiaodan X; Boue, Daniel D; Chow, Lionel M L LML; Finlay, Jonathan L JL; Gayden, Tenzin T; Karamchandani, Jason J; Hummel, Trent R TR; Olshefski, Randal R; Osorio, Diana S DS; Stevenson, Charles C; Kleinman, Claudia L CL; Majewski, Jacek J; Fouladi, Maryam M; Jabado, Nada N
Publication Date: 2017-10-30

Variant appearance in text: BRAF: V600V
PubMed Link: 29084603
Variant Present in the following documents:
  • 40478_2017_479_MOESM2_ESM.xlsx, sheet 12
  • 40478_2017_479_MOESM2_ESM.xlsx, sheet 13
View BVdb publication page



Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Oncotarget
Emelyanova, Marina M; Ghukasyan, Lilit L; Abramov, Ivan I; Ryabaya, Oxana O; Stepanova, Evgenia E; Kudryavtseva, Anna A; Sadritdinova, Asiya A; Dzhumakova, Cholpon C; Belysheva, Tatiana T; Surzhikov, Sergey S; Lyubchenko, Lyudmila L; Zasedatelev, Alexander A; Nasedkina, Tatiana T
Publication Date: 2017-08-08

Variant appearance in text: BRAF: V600V
PubMed Link: 28881731
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients.

International Journal Of Endocrinology
Yang, Li-Bo LB; Sun, Lin-Yong LY; Jiang, Yong Y; Tang, Ying Y; Li, Zhi-Hui ZH; Zhang, Hong-Ying HY; Bu, Hong H; Ye, Feng F
Publication Date: 2015

Variant appearance in text: BRAF: V600V
PubMed Link: 26273300
Variant Present in the following documents:
  • Main text
View BVdb publication page



Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

American Journal Of Cancer Research
Monsma, David J DJ; Cherba, David M DM; Eugster, Emily E EE; Dylewski, Dawna L DL; Davidson, Paula T PT; Peterson, Chelsea A CA; Borgman, Andrew S AS; Winn, Mary E ME; Dykema, Karl J KJ; Webb, Craig P CP; MacKeigan, Jeffrey P JP; Duesbery, Nicholas S NS; Nickoloff, Brian J BJ; Monks, Noel R NR
Publication Date: 2015

Variant appearance in text: BRAF: V600V
PubMed Link: 26101714
Variant Present in the following documents:
  • Main text
View BVdb publication page



Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.

Plos One
Sakai, Kazuko K; Tsurutani, Junji J; Yamanaka, Takeharu T; Yoneshige, Azusa A; Ito, Akihiko A; Togashi, Yosuke Y; De Velasco, Marco A MA; Terashima, Masato M; Fujita, Yoshihiko Y; Tomida, Shuta S; Tamura, Takao T; Nakagawa, Kazuhiko K; Nishio, Kazuto K
Publication Date: 2015

Variant appearance in text: BRAF: V600V
PubMed Link: 25954997
Variant Present in the following documents:
  • pone.0121891.s006.xlsx, sheet 1
View BVdb publication page



Anaplastic Transformation of Papillary Thyroid Carcinoma in a Young Man: A Case Study with Immunohistochemical and BRAF Analysis.

Korean Journal Of Pathology
Park, Ji Hye JH; Kwon, Hyeong Ju HJ; Park, Cheong Soo CS; Hong, SoonWon S
Publication Date: 2014-06

Variant appearance in text: BRAF: V600V
PubMed Link: 25013423
Variant Present in the following documents:
  • Main text
View BVdb publication page



BRAF pyrosequencing analysis aided by a lookup table.

American Journal Of Clinical Pathology
Olson, Matthew T MT; Harrington, Colleen C; Beierl, Katie K; Chen, Guoli G; Thiess, Michele M; O'Neill, Alan A; Taube, Janis M JM; Zeiger, Martha A MA; Lin, Ming-Tseh MT; Eshleman, James R JR
Publication Date: 2014-05

Variant appearance in text: BRAF: V600V
PubMed Link: 24713734
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular pathways: adaptive kinome reprogramming in response to targeted inhibition of the BRAF-MEK-ERK pathway in cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Johnson, Gary L GL; Stuhlmiller, Timothy J TJ; Angus, Steven P SP; Zawistowski, Jon S JS; Graves, Lee M LM
Publication Date: 2014-05-15

Variant appearance in text: BRAF: V600V
PubMed Link: 24664307
Variant Present in the following documents:
  • Main text
View BVdb publication page



Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nature Genetics
Brastianos, Priscilla K PK; Taylor-Weiner, Amaro A; Manley, Peter E PE; Jones, Robert T RT; Dias-Santagata, Dora D; Thorner, Aaron R AR; Lawrence, Michael S MS; Rodriguez, Fausto J FJ; Bernardo, Lindsay A LA; Schubert, Laura L; Sunkavalli, Ashwini A; Shillingford, Nick N; Calicchio, Monica L ML; Lidov, Hart G W HG; Taha, Hala H; Martinez-Lage, Maria M; Santi, Mariarita M; Storm, Phillip B PB; Lee, John Y K JY; Palmer, James N JN; Adappa, Nithin D ND; Scott, R Michael RM; Dunn, Ian F IF; Laws, Edward R ER; Stewart, Chip C; Ligon, Keith L KL; Hoang, Mai P MP; Van Hummelen, Paul P; Hahn, William C WC; Louis, David N DN; Resnick, Adam C AC; Kieran, Mark W MW; Getz, Gad G; Santagata, Sandro S
Publication Date: 2014-02

Variant appearance in text: BRAF: V600V
PubMed Link: 24413733
Variant Present in the following documents:
  • NIHMS547859-supplement-1.xlsx, sheet 3
View BVdb publication page



Development and validation of a clinical trial patient stratification assay that interrogates 27 mutation sites in MAPK pathway genes.

Plos One
Chang, Ken C N KC; Galuska, Stefan S; Weiner, Russell R; Marton, Matthew J MJ
Publication Date: 2013

Variant appearance in text: BRAF: V600V
PubMed Link: 23991070
Variant Present in the following documents:
  • Main text
  • pone.0072239.pdf
View BVdb publication page



Absence of BRAF exon 15 mutations in multiple myeloma and Waldenström's macroglobulinemia questions its validity as a therapeutic target in plasma cell neoplasias.

American Journal Of Blood Research
Hatzimichael, Eleftheria E; Murray, Samuel S; Briasoulis, Evangelos E
Publication Date: 2013

Variant appearance in text: BRAF: V600V
PubMed Link: 23675568
Variant Present in the following documents:
  • Main text
View BVdb publication page



KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.

Plos One
Mao, Chen C; Zhou, Junhua J; Yang, Zuyao Z; Huang, Yafang Y; Wu, Xinyin X; Shen, Hong H; Tang, Jinling J; Chen, Qing Q
Publication Date: 2012

Variant appearance in text: BRAF: V600V
PubMed Link: 22586484
Variant Present in the following documents:
  • Main text
  • pone.0036653.pdf
View BVdb publication page