Publications:

---

Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: BRAF: V600V

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM4_ESM.xls, sheet 2

View BVdb publication page

---

Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: BRAF: V600V

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

---

Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology

Georgoulias, George G; Zaravinos, Apostolos A

Publication Date: 2022

Variant appearance in text: BRAF: V600V

PubMed Link: 36389735

Variant Present in the following documents:

• Table_7.xlsx, sheet 8

View BVdb publication page

---

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

Cancer Research

Sjöström, Martin M; Zhao, Shuang G SG; Levy, Samuel S; Zhang, Meng M; Ning, Yuhong Y; Shrestha, Raunak R; Lundberg, Arian A; Herberts, Cameron C; Foye, Adam A; Aggarwal, Rahul R; Hua, Junjie T JT; Li, Haolong H; Bergamaschi, Anna A; Maurice-Dror, Corinne C; Maheshwari, Ashutosh A; Chen, Sujun S; Ng, Sarah W S SWS; Ye, Wenbin W; Petricca, Jessica J; Fraser, Michael M; Chesner, Lisa L; Perry, Marc D MD; Moreno-Rodriguez, Thaidy T; Chen, William S WS; Alumkal, Joshi J JJ; Chou, Jonathan J; Morgans, Alicia K AK; Beer, Tomasz M TM; Thomas, George V GV; Gleave, Martin M; Lloyd, Paul P; Phillips, Tierney T; McCarthy, Erin E; Haffner, Michael C MC; Zoubeidi, Amina A; Annala, Matti M; Reiter, Robert E RE; Rettig, Matthew B MB; Witte, Owen N ON; Fong, Lawrence L; Bose, Rohit R; Huang, Franklin W FW; Luo, Jianhua J; Bjartell, Anders A; Lang, Joshua M JM; Mahajan, Nupam P NP; Lara, Primo N PN; Evans, Christopher P CP; Tran, Phuoc T PT; Posadas, Edwin M EM; He, Chuan C; Cui, Xiao-Long XL; Huang, Jiaoti J; Zwart, Wilbert W; Gilbert, Luke A LA; Maher, Christopher A CA; Boutros, Paul C PC; Chi, Kim N KN; Ashworth, Alan A; Small, Eric J EJ; He, Housheng H HH; Wyatt, Alexander W AW; Quigley, David A DA; Feng, Felix Y FY

Publication Date: 2022-11-02

Variant appearance in text: BRAF: V600V

PubMed Link: 36251389

Variant Present in the following documents:

• can-22-1123_supplementary_table_3_suppst3.xlsx, sheet 1

View BVdb publication page

---

Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

The Journal Of Pathology

Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ

Publication Date: 2022-10-11

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 36219477

Variant Present in the following documents:

• PATH-259-56-s004.xlsx, sheet 2

View BVdb publication page

---

Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma.

Cancer Cell International

Affinito, Ornella O; Orlandella, Francesca Maria FM; Luciano, Neila N; Salvatore, Marco M; Salvatore, Giuliana G; Franzese, Monica M

Publication Date: 2022-08-22

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 35996174

Variant Present in the following documents:

• Main text
• 12935_2022_Article_2680.pdf
• 12935_2022_2680_MOESM5_ESM.xlsx, sheet 2

View BVdb publication page

---

PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer

Stein, Alexander A; Simnica, Donjete D; Schultheiß, Christoph C; Scholz, Rebekka R; Tintelnot, Joseph J; Gökkurt, Eray E; von Wenserski, Lisa L; Willscher, Edith E; Paschold, Lisa L; Sauer, Markus M; Lorenzen, Sylvie S; Riera-Knorrenschild, Jorge J; Depenbusch, Reinhard R; Ettrich, Thomas J TJ; Dörfel, Steffen S; Al-Batran, Salah-Eddin SE; Karthaus, Meinolf M; Pelzer, Uwe U; Waberer, Lisa L; Hinke, Axel A; Bauer, Marcus M; Massa, Chiara C; Seliger, Barbara B; Wickenhauser, Claudia C; Bokemeyer, Carsten C; Hegewisch-Becker, Susanna S; Binder, Mascha M

Publication Date: 2021-07

Variant appearance in text: BRAF: 1800G>A; Val600Val

PubMed Link: 34315821

Variant Present in the following documents:

• jitc-2021-002844supp002.xlsx, sheet 1

View BVdb publication page

---

Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics

Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM

Publication Date: 2020-12

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 33230298

Variant Present in the following documents:

• NIHMS1637640-supplement-SuppData1.xlsx, sheet 1

View BVdb publication page

---

Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.

Pigment Cell & Melanoma Research

Christodoulou, Eirini E; Rashid, Mamunur M; Pacini, Clare C; Droop, Alastair A; Robertson, Holly H; Groningen, Tim van TV; Teunisse, Amina F A S AFAS; Iorio, Francesco F; Jochemsen, Aart G AG; Adams, David J DJ; Doorn, Remco van RV

Publication Date: 2021-01

Variant appearance in text: BRAF: V600V

PubMed Link: 32767816

Variant Present in the following documents:

• PCMR-34-122-s006.xlsx, sheet 1

View BVdb publication page

---

A Rare Complex BRAF Mutation Involving Codon V600 and K601 in Primary Cutaneous Melanoma: Case Report.

Frontiers In Oncology

Consoli, Francesca F; Barbieri, Gianluca G; Picciolini, Matteo M; Medicina, Daniela D; Bugatti, Mattia M; Tovazzi, Valeria V; Liserre, Barbara B; Zambelli, Claudia C; Zorzi, Fausto F; Berruti, Alfredo A; Giurisato, Emanuele E; Vermi, William W

Publication Date: 2020

Variant appearance in text: BRAF: 1800G>A

PubMed Link: 32754440

Variant Present in the following documents:

• Main text
• fonc-10-01056.pdf

View BVdb publication page

---

Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy.

Iscience

Nagasawa, Ikuko I; Koido, Masaru M; Tani, Yuri Y; Tsukahara, Satomi S; Kunimasa, Kazuhiro K; Tomida, Akihiro A

Publication Date: 2020-04-24

Variant appearance in text: BRAF: V600V

PubMed Link: 32283529

Variant Present in the following documents:

• main.pdf
• mmc1.pdf

View BVdb publication page

---

Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: BRAF: V600V

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM13_ESM.xlsx, sheet 1

View BVdb publication page

---

Identification of 12 cancer types through genome deep learning.

Scientific Reports

Sun, Yingshuai Y; Zhu, Sitao S; Ma, Kailong K; Liu, Weiqing W; Yue, Yao Y; Hu, Gang G; Lu, Huifang H; Chen, Wenbin W

Publication Date: 2019-11-21

Variant appearance in text: BRAF: V600V

PubMed Link: 31754222

Variant Present in the following documents:

• 41598_2019_53989_MOESM4_ESM.xlsx, sheet 11
• 41598_2019_53989_MOESM4_ESM.xlsx, sheet 10

View BVdb publication page

---

Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer.

Scientific Reports

D'Oronzo, Stella S; Lovero, Domenica D; Palmirotta, Raffaele R; Stucci, Luigia Stefania LS; Tucci, Marco M; Felici, Claudia C; Cascardi, Eliano E; Giardina, Carmela C; Cafforio, Paola P; Silvestris, Franco F

Publication Date: 2019-11-21

Variant appearance in text: BRAF: V600V

PubMed Link: 31754145

Variant Present in the following documents:

• Main text
• 41598_2019_Article_53660.pdf
• 41598_2019_53660_MOESM1_ESM.pdf

View BVdb publication page

---

Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Robb, Ryan R; Yang, Linlin L; Shen, Changxian C; Wolfe, Adam R AR; Webb, Amy A; Zhang, Xiaoli X; Vedaie, Marall M; Saji, Motoyasu M; Jhiang, Sissy S; Ringel, Matthew D MD; Williams, Terence M TM

Publication Date: 2019-08-01

Variant appearance in text: BRAF: V600V

PubMed Link: 31097454

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Systemic Therapy in Metastatic Melanoma.

Federal Practitioner : For The Health Care Professionals Of The Va, Dod, And Phs

Goyal, Gaurav G; Silberstein, Peter T PT

Publication Date: 2015-05

Variant appearance in text: BRAF: V600V

PubMed Link: 30766124

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Bmc Cancer

Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Parida, Laxmi L

Publication Date: 2019-02-01

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 30709382

Variant Present in the following documents:

• 12885_2019_5313_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Patient-derived xenograft mouse models: A high fidelity tool for individualized medicine.

Oncology Letters

Xu, Cong C; Li, Xuelu X; Liu, Pixu P; Li, Man M; Luo, Fuwen F

Publication Date: 2019-01

Variant appearance in text: BRAF: V600V

PubMed Link: 30655732

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.

Journal Of Hematology & Oncology

Tessoulin, Benoît B; Moreau-Aubry, Agnès A; Descamps, Géraldine G; Gomez-Bougie, Patricia P; Maïga, Sophie S; Gaignard, Alban A; Chiron, David D; Ménoret, Emmanuelle E; Le Gouill, Steven S; Moreau, Philippe P; Amiot, Martine M; Pellat-Deceunynck, Catherine C

Publication Date: 2018-12-13

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 30545397

Variant Present in the following documents:

• 13045_2018_679_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures.

Scientific Reports

Collord, Grace G; Tarpey, Patrick P; Kurbatova, Natalja N; Martincorena, Inigo I; Moran, Sebastian S; Castro, Manuel M; Nagy, Tibor T; Bignell, Graham G; Maura, Francesco F; Young, Matthew D MD; Berna, Jorge J; Tubio, Jose M C JMC; McMurran, Chris E CE; Young, Adam M H AMH; Sanders, Mathijs M; Noorani, Imran I; Price, Stephen J SJ; Watts, Colin C; Leipnitz, Elke E; Kirsch, Matthias M; Schackert, Gabriele G; Pearson, Danita D; Devadass, Abel A; Ram, Zvi Z; Collins, V Peter VP; Allinson, Kieren K; Jenkinson, Michael D MD; Zakaria, Rasheed R; Syed, Khaja K; Hanemann, C Oliver CO; Dunn, Jemma J; McDermott, Michael W MW; Kirollos, Ramez W RW; Vassiliou, George S GS; Esteller, Manel M; Behjati, Sam S; Brazma, Alvis A; Santarius, Thomas T; McDermott, Ultan U

Publication Date: 2018-09-10

Variant appearance in text: BRAF: V600V

PubMed Link: 30202034

Variant Present in the following documents:

• 41598_2018_31659_MOESM2_ESM.xlsx, sheet 30

View BVdb publication page

---

From word models to executable models of signaling networks using automated assembly.

Molecular Systems Biology

Gyori, Benjamin M BM; Bachman, John A JA; Subramanian, Kartik K; Muhlich, Jeremy L JL; Galescu, Lucian L; Sorger, Peter K PK

Publication Date: 2017-11-24

Variant appearance in text: BRAF: V600=

PubMed Link: 29175850

Variant Present in the following documents:

• MSB-13-954-s001.pdf

View BVdb publication page

---

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Acta Neuropathologica Communications

Salloum, Ralph R; McConechy, Melissa K MK; Mikael, Leonie G LG; Fuller, Christine C; Drissi, Rachid R; DeWire, Mariko M; Nikbakht, Hamid H; De Jay, Nicolas N; Yang, Xiaodan X; Boue, Daniel D; Chow, Lionel M L LML; Finlay, Jonathan L JL; Gayden, Tenzin T; Karamchandani, Jason J; Hummel, Trent R TR; Olshefski, Randal R; Osorio, Diana S DS; Stevenson, Charles C; Kleinman, Claudia L CL; Majewski, Jacek J; Fouladi, Maryam M; Jabado, Nada N

Publication Date: 2017-10-30

Variant appearance in text: BRAF: V600V

PubMed Link: 29084603

Variant Present in the following documents:

• 40478_2017_479_MOESM2_ESM.xlsx, sheet 12
• 40478_2017_479_MOESM2_ESM.xlsx, sheet 13

View BVdb publication page

---

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Oncotarget

Emelyanova, Marina M; Ghukasyan, Lilit L; Abramov, Ivan I; Ryabaya, Oxana O; Stepanova, Evgenia E; Kudryavtseva, Anna A; Sadritdinova, Asiya A; Dzhumakova, Cholpon C; Belysheva, Tatiana T; Surzhikov, Sergey S; Lyubchenko, Lyudmila L; Zasedatelev, Alexander A; Nasedkina, Tatiana T

Publication Date: 2017-08-08

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 28881731

Variant Present in the following documents:

• Main text
• oncotarget-08-52304.pdf

View BVdb publication page

---

The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients.

International Journal Of Endocrinology

Yang, Li-Bo LB; Sun, Lin-Yong LY; Jiang, Yong Y; Tang, Ying Y; Li, Zhi-Hui ZH; Zhang, Hong-Ying HY; Bu, Hong H; Ye, Feng F

Publication Date: 2015

Variant appearance in text: N/A

PubMed Link: 26273300

Variant Present in the following documents:

View BVdb publication page

---

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

American Journal Of Cancer Research

Monsma, David J DJ; Cherba, David M DM; Eugster, Emily E EE; Dylewski, Dawna L DL; Davidson, Paula T PT; Peterson, Chelsea A CA; Borgman, Andrew S AS; Winn, Mary E ME; Dykema, Karl J KJ; Webb, Craig P CP; MacKeigan, Jeffrey P JP; Duesbery, Nicholas S NS; Nickoloff, Brian J BJ; Monks, Noel R NR

Publication Date: 2015

Variant appearance in text: N/A

PubMed Link: 26101714

Variant Present in the following documents:

View BVdb publication page

---

Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.

Plos One

Sakai, Kazuko K; Tsurutani, Junji J; Yamanaka, Takeharu T; Yoneshige, Azusa A; Ito, Akihiko A; Togashi, Yosuke Y; De Velasco, Marco A MA; Terashima, Masato M; Fujita, Yoshihiko Y; Tomida, Shuta S; Tamura, Takao T; Nakagawa, Kazuhiko K; Nishio, Kazuto K

Publication Date: 2015

Variant appearance in text: BRAF: V600V

PubMed Link: 25954997

Variant Present in the following documents:

• pone.0121891.s006.xlsx, sheet 1

View BVdb publication page

---

Anaplastic Transformation of Papillary Thyroid Carcinoma in a Young Man: A Case Study with Immunohistochemical and BRAF Analysis.

Korean Journal Of Pathology

Park, Ji Hye JH; Kwon, Hyeong Ju HJ; Park, Cheong Soo CS; Hong, SoonWon S

Publication Date: 2014-06

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 25013423

Variant Present in the following documents:

• Main text
• kjpathol-48-234.pdf

View BVdb publication page

---

BRAF pyrosequencing analysis aided by a lookup table.

American Journal Of Clinical Pathology

Olson, Matthew T MT; Harrington, Colleen C; Beierl, Katie K; Chen, Guoli G; Thiess, Michele M; O'Neill, Alan A; Taube, Janis M JM; Zeiger, Martha A MA; Lin, Ming-Tseh MT; Eshleman, James R JR

Publication Date: 2014-05

Variant appearance in text: BRAF: 1800G>A; V600V

PubMed Link: 24713734

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular pathways: adaptive kinome reprogramming in response to targeted inhibition of the BRAF-MEK-ERK pathway in cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Johnson, Gary L GL; Stuhlmiller, Timothy J TJ; Angus, Steven P SP; Zawistowski, Jon S JS; Graves, Lee M LM

Publication Date: 2014-05-15

Variant appearance in text: N/A

PubMed Link: 24664307

Variant Present in the following documents:

View BVdb publication page

---

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nature Genetics

Brastianos, Priscilla K PK; Taylor-Weiner, Amaro A; Manley, Peter E PE; Jones, Robert T RT; Dias-Santagata, Dora D; Thorner, Aaron R AR; Lawrence, Michael S MS; Rodriguez, Fausto J FJ; Bernardo, Lindsay A LA; Schubert, Laura L; Sunkavalli, Ashwini A; Shillingford, Nick N; Calicchio, Monica L ML; Lidov, Hart G W HG; Taha, Hala H; Martinez-Lage, Maria M; Santi, Mariarita M; Storm, Phillip B PB; Lee, John Y K JY; Palmer, James N JN; Adappa, Nithin D ND; Scott, R Michael RM; Dunn, Ian F IF; Laws, Edward R ER; Stewart, Chip C; Ligon, Keith L KL; Hoang, Mai P MP; Van Hummelen, Paul P; Hahn, William C WC; Louis, David N DN; Resnick, Adam C AC; Kieran, Mark W MW; Getz, Gad G; Santagata, Sandro S

Publication Date: 2014-02

Variant appearance in text: BRAF: V600V

PubMed Link: 24413733

Variant Present in the following documents:

• NIHMS547859-supplement-1.xlsx, sheet 3

View BVdb publication page

---

Development and validation of a clinical trial patient stratification assay that interrogates 27 mutation sites in MAPK pathway genes.

Plos One

Chang, Ken C N KC; Galuska, Stefan S; Weiner, Russell R; Marton, Matthew J MJ

Publication Date: 2013

Variant appearance in text: BRAF: V600V

PubMed Link: 23991070

Variant Present in the following documents:

• Main text
• pone.0072239.pdf

View BVdb publication page

---

Absence of BRAF exon 15 mutations in multiple myeloma and Waldenström's macroglobulinemia questions its validity as a therapeutic target in plasma cell neoplasias.

American Journal Of Blood Research

Hatzimichael, Eleftheria E; Murray, Samuel S; Briasoulis, Evangelos E

Publication Date: 2013

Variant appearance in text: N/A

PubMed Link: 23675568

Variant Present in the following documents:

View BVdb publication page

---

KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.

Plos One

Mao, Chen C; Zhou, Junhua J; Yang, Zuyao Z; Huang, Yafang Y; Wu, Xinyin X; Shen, Hong H; Tang, Jinling J; Chen, Qing Q

Publication Date: 2012

Variant appearance in text: BRAF: V600V

PubMed Link: 22586484

Variant Present in the following documents:

• Main text
• pone.0036653.pdf

View BVdb publication page

---

Comparison of allelic discrimination by dHPLC, HRM, and TaqMan in the detection of BRAF mutation V600E.

The Journal Of Molecular Diagnostics : Jmd

Carbonell, Pablo P; Turpin, María C MC; Torres-Moreno, Daniel D; Molina-Martínez, Irene I; García-Solano, José J; Perez-Guillermo, Miguel M; Conesa-Zamora, Pablo P

Publication Date: 2011-09

Variant appearance in text: BRAF: 1800G>A

PubMed Link: 21708284

Variant Present in the following documents:

• Main text

View BVdb publication page

---