BRAF c.1799_1800delinsAT ;(p.V600D)

Variant ID: 7-140453135-CA-AT

NM_004333.4(BRAF):c.1799_1800delinsAT;(p.V600D)

This variant was identified in 193 publications

View GRCh38 version.




Publications:


Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: V600D; rs121913377
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



A prognostic risk model for glioma patients by systematic evaluation of genomic variations.

Iscience
Zhang, Baifeng B; Wan, Weiqing W; Li, Zibo Z; Gao, Zhixian Z; Ji, Nan N; Xie, Jian J; Wang, Junmei J; Wang, Bin B; Lai-Wan Kwong, Dora D; Guan, Xinyuan X; Gao, Shengjie S; Zhao, Yuanli Y; Lu, Youyong Y; Zhang, Liwei L; Rodland, Karin D KD; Tsang, Shirley X SX
Publication Date: 2022-12-22

Variant appearance in text: rs121913377
PubMed Link: 36536675
Variant Present in the following documents:
  • mmc3.xls, sheet 1
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: N/A
PubMed Link: 35936718
Variant Present in the following documents:
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: N/A
PubMed Link: 35835912
Variant Present in the following documents:
View BVdb publication page



Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

Plos One
Williams, Gareth G; Llewelyn, Alexander A; Thatcher, Robert R; Hardisty, Keeda-Marie KM; Loddo, Marco M
Publication Date: 2022

Variant appearance in text: rs121913377
PubMed Link: 35324914
Variant Present in the following documents:
  • pone.0245817.s005.pdf
View BVdb publication page



BRAF V600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis.

Haematologica
Kudo, Ko K; Toki, Tsutomu T; Kanezaki, Rika R; Tanaka, Tatsuhiko T; Kamio, Takuya T; Sato, Tomohiko T; Sasaki, Shinya S; Imamura, Masaru M; Imai, Chihaya C; Ando, Kumiko K; Kakuda, Harumi H; Doi, Takehiko T; Kawaguchi, Hiroshi H; Irie, Masahiro M; Sasahara, Yoji Y; Tamura, Akihiro A; Hasegawa, Daiichiro D; Itakura, Yosuke Y; Watanabe, Kenichiro K; Sakamoto, Kenichi K; Shioda, Yoko Y; Kato, Motohiro M; Kudo, Kazuko K; Fukano, Reiji R; Sato, Atsushi A; Yagasaki, Hiroshi H; Kanegane, Hirokazu H; Kato, Itaru I; Umeda, Katsutsugu K; Adachi, Souichi S; Kataoka, Tatsuki T; Kurose, Akira A; Nakazawa, Atsuko A; Terui, Kiminori K; Ito, Etsuro E
Publication Date: 2022-07-01

Variant appearance in text: BRAF: 1799_1800delTGinsAT; Val600Asp
PubMed Link: 35295077
Variant Present in the following documents:
  • 2021_279857_KUDO_SUPPL.pdf
View BVdb publication page



Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies.

The Journal Of Pathology
Cyrta, Joanna J; Prandi, Davide D; Arora, Arshi A; Hovelson, Daniel H DH; Sboner, Andrea A; Rodriguez, Antonio A; Fedrizzi, Tarcisio T; Beltran, Himisha H; Robinson, Dan R DR; Gopalan, Anuradha A; True, Lawrence L; Nelson, Peter S PS; Robinson, Brian D BD; Mosquera, Juan Miguel JM; Tomlins, Scott A SA; Shen, Ronglai R; Demichelis, Francesca F; Rubin, Mark A MA
Publication Date: 2022-07

Variant appearance in text: rs121913377
PubMed Link: 35220606
Variant Present in the following documents:
  • PATH-257-274-s001.xlsx, sheet 4
View BVdb publication page



Mechanistically Coupled PK (MCPK) Model to Describe Enzyme Induction and Occupancy Dependent DDI of Dabrafenib Metabolism.

Pharmaceutics
Albrecht, Marco M; Kogan, Yuri Y; Kulms, Dagmar D; Sauter, Thomas T
Publication Date: 2022-01-28

Variant appearance in text: N/A
PubMed Link: 35214043
Variant Present in the following documents:
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913377
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913377
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 8
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 34630336
Variant Present in the following documents:
View BVdb publication page



High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports
Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K
Publication Date: 2021-07

Variant appearance in text: rs121913377
PubMed Link: 34590037
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Genomic and transcriptomic landscape of conjunctival melanoma.

Plos Genetics
Cisarova, Katarina K; Folcher, Marc M; El Zaoui, Ikram I; Pescini-Gobert, Rosanna R; Peter, Virginie G VG; Royer-Bertrand, Beryl B; Zografos, Leonidas L; Schalenbourg, Ann A; Nicolas, Michael M; Rimoldi, Donata D; Leyvraz, Serge S; Riggi, Nicolò N; Moulin, Alexandre P AP; Rivolta, Carlo C
Publication Date: 2020-12

Variant appearance in text: rs121913377
PubMed Link: 33383577
Variant Present in the following documents:
  • pgen.1009201.s006.xlsx, sheet 1
View BVdb publication page



Genotyping data of routinely processed matched primary/metastatic tumor samples.

Data In Brief
Kotoula, Vassiliki V; Chatzopoulos, Kyriakos K; Papadopoulou, Kyriaki K; Giannoulatou, Eleni E; Koliou, Georgia-Angeliki GA; Karavasilis, Vasilios V; Pazarli, Elissavet E; Pervana, Stavroula S; Kafiri, Georgia G; Tsoulfas, Georgios G; Chrisafi, Sofia S; Sgouramali, Helen H; Papakostas, Pavlos P; Pectasides, Dimitrios D; Hytiroglou, Prodromos P; Pentheroudakis, George G; Fountzilas, George G
Publication Date: 2021-02

Variant appearance in text: rs121913377
PubMed Link: 33365374
Variant Present in the following documents:
  • mmc1.xlsx, sheet 3
View BVdb publication page



Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics
Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM
Publication Date: 2020-12

Variant appearance in text: rs121913377
PubMed Link: 33230298
Variant Present in the following documents:
  • NIHMS1637640-supplement-SuppData1.xlsx, sheet 1
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913377
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach.

Journal Of Translational Medicine
Manca, Antonella A; Paliogiannis, Panagiotis P; Colombino, Maria M; Casula, Milena M; Lissia, Amelia A; Botti, Gerardo G; Caracò, Corrado C; Ascierto, Paolo A PA; Sini, Maria Cristina MC; Palomba, Grazia G; Pisano, Marina M; , ; , ; Doneddu, Valentina V; Cossu, Antonio A; Palmieri, Giuseppe G; ,
Publication Date: 2019-08-28

Variant appearance in text: rs121913377
PubMed Link: 31455347
Variant Present in the following documents:
  • 12967_2019_2039_MOESM1_ESM.xlsx, sheet 1
  • 12967_2019_2039_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs).

Clinical Sarcoma Research
Heinrich, Michael C MC; Patterson, Janice J; Beadling, Carol C; Wang, Yuexiang Y; Debiec-Rychter, Maria M; Dewaele, Barbara B; Corless, Christopher L CL; Duensing, Anette A; Raut, Chandrajit P CP; Rubin, Brian B; Ordog, Tamas T; van de Rijn, Matt M; Call, Jerry J; Mühlenberg, Thomas T; Fletcher, Jonathan A JA; Bauer, Sebastian S
Publication Date: 2019

Variant appearance in text: rs121913377
PubMed Link: 30867899
Variant Present in the following documents:
  • 13569_2019_112_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer.

Ebiomedicine
Liu, Xiaoyu X; Liu, Lingxiao L; Ji, Yuan Y; Li, Changyu C; Wei, Tao T; Yang, Xuerong X; Zhang, Yuefang Y; Cai, Xuyu X; Gao, Yangbin Y; Xu, Weihong W; Rao, Shengxiang S; Jin, Dayong D; Lou, Wenhui W; Qiu, Zilong Z; Wang, Xiaolin X
Publication Date: 2019-03

Variant appearance in text: BRAF: V600D; rs121913377
PubMed Link: 30857943
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.

Plos One
Ackermann, Anne A; Schrecker, Christopher C; Bon, Dimitra D; Friedrichs, Nicolaus N; Bankov, Katrin K; Wild, Peter P; Plotz, Guido G; Zeuzem, Stefan S; Herrmann, Eva E; Hansmann, Martin-Leo ML; Brieger, Angela A
Publication Date: 2019

Variant appearance in text: N/A
PubMed Link: 30856214
Variant Present in the following documents:
View BVdb publication page



Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma.

Npj Systems Biology And Applications
Del Mistro, Greta G; Lucarelli, Philippe P; Müller, Ines I; De Landtsheer, Sébastien S; Zinoveva, Anna A; Hutt, Meike M; Siegemund, Martin M; Kontermann, Roland E RE; Beissert, Stefan S; Sauter, Thomas T; Kulms, Dagmar D
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 30416750
Variant Present in the following documents:
View BVdb publication page



Novel BRAF alteration in desmoplastic infantile ganglioglioma with response to targeted therapy.

Acta Neuropathologica Communications
Blessing, Melissa M MM; Blackburn, Patrick R PR; Balcom, Jessica R JR; Krishnan, Chandra C; Harrod, Virginia L VL; Zimmermann, Michael T MT; Barr Fritcher, Emily G EG; Zysk, Christopher D CD; Jackson, Rory A RA; Nair, Asha A AA; Jenkins, Robert B RB; Halling, Kevin C KC; Kipp, Benjamin R BR; Ida, Cristiane M CM
Publication Date: 2018-11-05

Variant appearance in text: N/A
PubMed Link: 30396366
Variant Present in the following documents:
View BVdb publication page



The Importance of the Right Framework: Mitogen-Activated Protein Kinase Pathway and the Scaffolding Protein PTPIP51.

International Journal Of Molecular Sciences
Dietel, Eric E; Brobeil, Alexander A; Gattenlöhner, Stefan S; Wimmer, Monika M
Publication Date: 2018-10-22

Variant appearance in text: N/A
PubMed Link: 30360441
Variant Present in the following documents:
View BVdb publication page



Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.

Oncotarget
Del Carmen, Sofía S; Sayagués, José María JM; Bengoechea, Oscar O; Anduaga, María Fernanda MF; Alcazar, Jose Antonio JA; Gervas, Ruth R; García, Jacinto J; Orfao, Alberto A; Bellvis, Luis Muñoz LM; Sarasquete, María Eugenia ME; Del Mar Abad, María M
Publication Date: 2018-09-28

Variant appearance in text: N/A
PubMed Link: 30344942
Variant Present in the following documents:
View BVdb publication page



Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma.

Radiology And Oncology
Moltara, Maja Ebert ME; Novakovic, Srdjan S; Boc, Marko M; Bucic, Marina M; Rebersek, Martina M; Zadnik, Vesna V; Ocvirk, Janja J
Publication Date: 2018-04-26

Variant appearance in text: N/A
PubMed Link: 30210039
Variant Present in the following documents:
View BVdb publication page



Biology and treatment of BRAF mutant metastatic melanoma.

Melanoma Management
Kong, Benjamin Y BY; Carlino, Matteo S MS; Menzies, Alexander M AM
Publication Date: 2016-03

Variant appearance in text: N/A
PubMed Link: 30190871
Variant Present in the following documents:
View BVdb publication page



Dabrafenib and its use in the treatment of metastatic melanoma.

Melanoma Management
Bowyer, Samantha S; Lee, Rebecca R; Fusi, Alberto A; Lorigan, Paul P
Publication Date: 2015-08

Variant appearance in text: N/A
PubMed Link: 30190849
Variant Present in the following documents:
View BVdb publication page



Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells.

International Journal Of Oncology
Fratangelo, Federica F; Camerlingo, Rosa R; Carriero, Maria Vincenza MV; Pirozzi, Giuseppe G; Palmieri, Giuseppe G; Gentilcore, Giusy G; Ragone, Concetta C; Minopoli, Michele M; Ascierto, Paolo Antonio PA; Motti, Maria Letizia ML
Publication Date: 2018-09

Variant appearance in text: N/A
PubMed Link: 29956724
Variant Present in the following documents:
View BVdb publication page



The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget
Liu, Zhe Z; Yang, Chao C; Li, Xiangchun X; Luo, Wen W; Roy, Bhaskar B; Xiong, Teng T; Zhang, Xiuqing X; Yang, Huanming H; Wang, Jian J; Ye, Zhenhao Z; Chen, Yang Y; Song, Jinghe J; Ma, Shuai S; Zhou, Yong Y; Yang, Min M; Fang, Xiaodong X; Du, Jie J
Publication Date: 2018-06-08

Variant appearance in text: rs121913377
PubMed Link: 29937994
Variant Present in the following documents:
  • oncotarget-09-27412-s004.xlsx, sheet 1
View BVdb publication page



Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.

Plos One
Chat-Uthai, Nunthawut N; Vejvisithsakul, Pichpisith P; Udommethaporn, Sutthirat S; Meesiri, Puttarakun P; Danthanawanit, Chetiya C; Wongchai, Yannawan Y; Teerapakpinyo, Chinachote C; Shuangshoti, Shanop S; Poungvarin, Naravat N
Publication Date: 2018

Variant appearance in text: BRAF: 1799_1800delTGinsAT; V600D
PubMed Link: 29879227
Variant Present in the following documents:
  • Main text
  • pone.0198795.pdf
View BVdb publication page



Reversal of Resistance in Targeted Therapy of Metastatic Melanoma: Lessons Learned from Vemurafenib (BRAFV600E-Specific Inhibitor).

Cancers
Torres-Collado, Antoni Xavier AX; Knott, Jeffrey J; Jazirehi, Ali R AR
Publication Date: 2018-05-24

Variant appearance in text: N/A
PubMed Link: 29795041
Variant Present in the following documents:
View BVdb publication page



Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior.

Elife
Sadeghi, Rochelle Shirin RS; Kulej, Katarzyna K; Kathayat, Rahul Singh RS; Garcia, Benjamin A BA; Dickinson, Bryan C BC; Brady, Donita C DC; Witze, Eric S ES
Publication Date: 2018-04-12

Variant appearance in text: N/A
PubMed Link: 29648538
Variant Present in the following documents:
View BVdb publication page



Genetic alterations in main candidate genes during melanoma progression.

Oncotarget
Sini, Maria Cristina MC; Doneddu, Valentina V; Paliogiannis, Panagiotis P; Casula, Milena M; Colombino, Maria M; Manca, Antonella A; Botti, Gerardo G; Ascierto, Paolo A PA; Lissia, Amelia A; Cossu, Antonio A; Palmieri, Giuseppe G
Publication Date: 2018-02-02

Variant appearance in text: N/A
PubMed Link: 29492214
Variant Present in the following documents:
View BVdb publication page



17-AAG inhibits vemurafenib-associated MAP kinase activation and is synergistic with cellular immunotherapy in a murine melanoma model.

Plos One
Joshi, Sandeep S SS; Jiang, Shunlin S; Unni, Emmanual E; Goding, Stephen R SR; Fan, Tao T; Antony, Paul A PA; Hornyak, Thomas J TJ
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 29481571
Variant Present in the following documents:
View BVdb publication page



Melanoma Brain Metastases: Local Therapies, Targeted Therapies, Immune Checkpoint Inhibitors and Their Combinations-Chances and Challenges.

American Journal Of Clinical Dermatology
Kuske, Marvin M; Rauschenberg, Ricarda R; Garzarolli, Marlene M; Meredyth-Stewart, Michelle M; Beissert, Stefan S; Troost, Esther G C EGC; Glitza, Oliva Isabella Claudia OIC; Meier, Friedegund F
Publication Date: 2018-08

Variant appearance in text: N/A
PubMed Link: 29417399
Variant Present in the following documents:
View BVdb publication page



Rapid BRAF mutation tests in patients with advanced melanoma: comparison of immunohistochemistry, Droplet Digital PCR, and the Idylla Mutation Platform.

Melanoma Research
Bisschop, Cornelis C; Ter Elst, Arja A; Bosman, Lisette J LJ; Platteel, Inge I; Jalving, Mathilde M; van den Berg, Anke A; Diepstra, Arjan A; van Hemel, Bettien B; Diercks, Gilles F H GFH; Hospers, Geke A P GAP; Schuuring, Ed E
Publication Date: 2018-04

Variant appearance in text: N/A
PubMed Link: 29232304
Variant Present in the following documents:
View BVdb publication page



Variables that influence BRAF mutation probability: A next-generation sequencing, non-interventional investigation of BRAFV600 mutation status in melanoma.

Plos One
Gaiser, Maria Rita MR; Skorokhod, Alexander A; Gransheier, Diana D; Weide, Benjamin B; Koch, Winfried W; Schif, Birgit B; Enk, Alexander A; Garbe, Claus C; Bauer, Jürgen J
Publication Date: 2017

Variant appearance in text: N/A
PubMed Link: 29176861
Variant Present in the following documents:
View BVdb publication page



Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
Cheng, Liang L; Lopez-Beltran, Antonio A; Massari, Francesco F; MacLennan, Gregory T GT; Montironi, Rodolfo R
Publication Date: 2018-01

Variant appearance in text: N/A
PubMed Link: 29148538
Variant Present in the following documents:
View BVdb publication page



Overcoming resistance to BRAF inhibitors.

Annals Of Translational Medicine
Arozarena, Imanol I; Wellbrock, Claudia C
Publication Date: 2017-10

Variant appearance in text: N/A
PubMed Link: 29114545
Variant Present in the following documents:
View BVdb publication page



New perspectives for targeting RAF kinase in human cancer.

Nature Reviews. Cancer
Karoulia, Zoi Z; Gavathiotis, Evripidis E; Poulikakos, Poulikos I PI
Publication Date: 2017-11

Variant appearance in text: N/A
PubMed Link: 28984291
Variant Present in the following documents:
View BVdb publication page



Distinct clinicopathological features in metanephric adenoma harboring BRAF mutation.

Oncotarget
Caliò, Anna A; Eble, John N JN; Hes, Ondrej O; Martignoni, Guido G; Harari, Saul E SE; Williamson, Sean R SR; Brunelli, Matteo M; Osunkoya, Adeboye O AO; Wang, Lisha L; Comperat, Eva E; Lopez-Beltran, Antonio A; Wang, Mingsheng M; Zhang, Shaobo S; Curless, Kendra L KL; Post, Kristin M KM; Chang, Hsim-Yee HY; Luchini, Claudio C; Baldrige, Lee Ann LA; MacLennan, Gregory T GT; Montironi, Rodolfo R; Grignon, David J DJ; Cheng, Liang L
Publication Date: 2017-08-15

Variant appearance in text: N/A
PubMed Link: 28903326
Variant Present in the following documents:
View BVdb publication page



Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.

Oncotarget
Emelyanova, Marina M; Ghukasyan, Lilit L; Abramov, Ivan I; Ryabaya, Oxana O; Stepanova, Evgenia E; Kudryavtseva, Anna A; Sadritdinova, Asiya A; Dzhumakova, Cholpon C; Belysheva, Tatiana T; Surzhikov, Sergey S; Lyubchenko, Lyudmila L; Zasedatelev, Alexander A; Nasedkina, Tatiana T
Publication Date: 2017-08-08

Variant appearance in text: BRAF: 1799_1800delTGinsAT; V600D
PubMed Link: 28881731
Variant Present in the following documents:
  • Main text
  • oncotarget-08-52304-s002.xlsx, sheet 1
  • oncotarget-08-52304.pdf
View BVdb publication page



Putative genomic characteristics of BRAF V600K versus V600E cutaneous melanoma.

Melanoma Research
Li, Yuanyuan Y; Umbach, David M DM; Li, Leping L
Publication Date: 2017-12

Variant appearance in text: N/A
PubMed Link: 28858076
Variant Present in the following documents:
View BVdb publication page



Associations of MC1R Genotype and Patient Phenotypes with BRAF and NRAS Mutations in Melanoma.

The Journal Of Investigative Dermatology
Thomas, Nancy E NE; Edmiston, Sharon N SN; Kanetsky, Peter A PA; Busam, Klaus J KJ; Kricker, Anne A; Armstrong, Bruce K BK; Cust, Anne E AE; Anton-Culver, Hoda H; Gruber, Stephen B SB; Luo, Li L; Orlow, Irene I; Reiner, Anne S AS; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Sacchetto, Lidia L; Dwyer, Terence T; Parrish, Eloise A EA; Hao, Honglin H; Gibbs, David C DC; Frank, Jill S JS; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Conway, Kathleen K; ,
Publication Date: 2017-12

Variant appearance in text: N/A
PubMed Link: 28842324
Variant Present in the following documents:
View BVdb publication page



Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma.

Case Reports In Oncological Medicine
Vittal, Anusha A; Middinti, Akshay A; Kasi Loknath Kumar, Anup A
Publication Date: 2017

Variant appearance in text: N/A
PubMed Link: 28811946
Variant Present in the following documents:
View BVdb publication page



Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Nature
Yao, Zhan Z; Yaeger, Rona R; Rodrik-Outmezguine, Vanessa S VS; Tao, Anthony A; Torres, Neilawattie M NM; Chang, Matthew T MT; Drosten, Matthias M; Zhao, Huiyong H; Cecchi, Fabiola F; Hembrough, Todd T; Michels, Judith J; Baumert, Hervé H; Miles, Linde L; Campbell, Naomi M NM; de Stanchina, Elisa E; Solit, David B DB; Barbacid, Mariano M; Taylor, Barry S BS; Rosen, Neal N
Publication Date: 2017-08-10

Variant appearance in text: N/A
PubMed Link: 28783719
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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: N/A
PubMed Link: 28775315
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New somatic BRAF splicing mutation in Langerhans cell histiocytosis.

Molecular Cancer
Héritier, Sébastien S; Hélias-Rodzewicz, Zofia Z; Chakraborty, Rikhia R; Sengal, Amel G AG; Bellanné-Chantelot, Christine C; Thomas, Caroline C; Moreau, Anne A; Fraitag, Sylvie S; Allen, Carl E CE; Donadieu, Jean J; Emile, Jean-François JF
Publication Date: 2017-07-06

Variant appearance in text: N/A
PubMed Link: 28679432
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Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

British Journal Of Cancer
Alvi, Muhammad A MA; Loughrey, Maurice B MB; Dunne, Philip P; McQuaid, Stephen S; Turkington, Richard R; Fuchs, Marc-Aurel MA; McGready, Claire C; Bingham, Victoria V; Pang, Brendan B; Moore, Wendy W; Maxwell, Perry P; Lawler, Mark M; James, Jacqueline A JA; Murray, Graeme I GI; Wilson, Richard H RH; Salto-Tellez, Manuel M
Publication Date: 2017-07-11

Variant appearance in text: rs121913377
PubMed Link: 28595259
Variant Present in the following documents:
  • bjc2017168x11.xlsx, sheet 1
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Dabrafenib plus trametinib in patients with BRAFV600-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial.

The Lancet. Oncology
Davies, Michael A MA; Saiag, Philippe P; Robert, Caroline C; Grob, Jean-Jacques JJ; Flaherty, Keith T KT; Arance, Ana A; Chiarion-Sileni, Vanna V; Thomas, Luc L; Lesimple, Thierry T; Mortier, Laurent L; Moschos, Stergios J SJ; Hogg, David D; Márquez-Rodas, Iván I; Del Vecchio, Michele M; Lebbé, Céleste C; Meyer, Nicolas N; Zhang, Ying Y; Huang, Yingjie Y; Mookerjee, Bijoyesh B; Long, Georgina V GV
Publication Date: 2017-07

Variant appearance in text: N/A
PubMed Link: 28592387
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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: BRAF: V600D; rs121913377
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
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HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers.

The Journal Of Biological Chemistry
Zhao, Liang L; Fan, Jun J; Xia, Siyuan S; Pan, Yaozhu Y; Liu, Shuangping S; Qian, Guoqing G; Qian, Zhiyu Z; Kang, Hee-Bum HB; Arbiser, Jack L JL; Pollack, Brian P BP; Kudchadkar, Ragini R RR; Lawson, David H DH; Rossi, Michael M; Abdel-Wahab, Omar O; Merghoub, Taha T; Khoury, Hanna J HJ; Khuri, Fadlo R FR; Boise, Lawrence H LH; Lonial, Sagar S; Chen, Fangping F; Chen, Jing J; Lin, Ruiting R
Publication Date: 2017-06-16

Variant appearance in text: N/A
PubMed Link: 28468827
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BRAFV600 mutations in solid tumors, other than metastatic melanoma and papillary thyroid cancer, or multiple myeloma: a screening study.

Oncotargets And Therapy
Cohn, Allen L AL; Day, Bann-Mo BM; Abhyankar, Sarang S; McKenna, Edward E; Riehl, Todd T; Puzanov, Igor I
Publication Date: 2017

Variant appearance in text: N/A
PubMed Link: 28255242
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Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition.

Scientific Reports
Hardeman, Keisha N KN; Peng, Chengwei C; Paudel, Bishal B BB; Meyer, Christian T CT; Luong, Thong T; Tyson, Darren R DR; Young, Jamey D JD; Quaranta, Vito V; Fessel, Joshua P JP
Publication Date: 2017-02-16

Variant appearance in text: N/A
PubMed Link: 28205616
Variant Present in the following documents:
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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications
Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML
Publication Date: 2017-02-10

Variant appearance in text: rs121913377
PubMed Link: 28186126
Variant Present in the following documents:
  • ncomms14262-s5.xlsx, sheet 2
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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: N/A
PubMed Link: 28179366
Variant Present in the following documents:
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A variant by any name: quantifying annotation discordance across tools and clinical databases.

Genome Medicine
Yen, Jennifer L JL; Garcia, Sarah S; Montana, Aldrin A; Harris, Jason J; Chervitz, Stephen S; Morra, Massimo M; West, John J; Chen, Richard R; Church, Deanna M DM
Publication Date: 2017-01-26

Variant appearance in text: BRAF: 1799_1800delTGinsAT; V600D
PubMed Link: 28122645
Variant Present in the following documents:
  • Main text
  • 13073_2016_Article_396.pdf
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MicroRNAs in melanoma development and resistance to target therapy.

Oncotarget
Fattore, Luigi L; Costantini, Susan S; Malpicci, Debora D; Ruggiero, Ciro Francesco CF; Ascierto, Paolo Antonio PA; Croce, Carlo M CM; Mancini, Rita R; Ciliberto, Gennaro G
Publication Date: 2017-03-28

Variant appearance in text: N/A
PubMed Link: 28118616
Variant Present in the following documents:
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Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.

Cell Metabolism
Xia, Siyuan S; Lin, Ruiting R; Jin, Lingtao L; Zhao, Liang L; Kang, Hee-Bum HB; Pan, Yaozhu Y; Liu, Shuangping S; Qian, Guoqing G; Qian, Zhiyu Z; Konstantakou, Evmorfia E; Zhang, Baotong B; Dong, Jin-Tang JT; Chung, Young Rock YR; Abdel-Wahab, Omar O; Merghoub, Taha T; Zhou, Lu L; Kudchadkar, Ragini R RR; Lawson, David H DH; Khoury, Hanna J HJ; Khuri, Fadlo R FR; Boise, Lawrence H LH; Lonial, Sagar S; Lee, Benjamin H BH; Pollack, Brian P BP; Arbiser, Jack L JL; Fan, Jun J; Lei, Qun-Ying QY; Chen, Jing J
Publication Date: 2017-02-07

Variant appearance in text: N/A
PubMed Link: 28089569
Variant Present in the following documents:
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hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma.

Cell Death Discovery
Fleten, Karianne G KG; Flørenes, Vivi Ann VA; Prasmickaite, Lina L; Hill, Oliver O; Sykora, Jaromir J; Mælandsmo, Gunhild M GM; Engesæter, Birgit B
Publication Date: 2016

Variant appearance in text: N/A
PubMed Link: 28028438
Variant Present in the following documents:
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BRAF inhibitors and radiotherapy for melanoma brain metastases: potential advantages and disadvantages of combination therapy.

Oncotargets And Therapy
Chowdhary, Mudit M; Patel, Kirtesh R KR; Danish, Hasan H HH; Lawson, David H DH; Khan, Mohammad K MK
Publication Date: 2016

Variant appearance in text: N/A
PubMed Link: 28003758
Variant Present in the following documents:
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Desmoplastic infantile astrocytoma/ganglioglioma with rare BRAF V600D mutation.

Pediatric Blood & Cancer
Greer, Ashley A; Foreman, Nicholas K NK; Donson, Andrew A; Davies, Kurtis D KD; Kleinschmidt-DeMasters, B K BK
Publication Date: 2017-06

Variant appearance in text: N/A
PubMed Link: 27860162
Variant Present in the following documents:
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Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.

Oncotarget
Mukherjee, Nabanita N; Almeida, Adam A; Partyka, Katie A KA; Lu, Yan Y; Schwan, Josianna V JV; Lambert, Karoline K; Rogers, Madison M; Robinson, William A WA; Robinson, Steven E SE; Applegate, Allison J AJ; Amato, Carol M CM; Luo, Yuchun Y; Fujita, Mayumi M; Norris, David A DA; Shellman, Yiqun G YG
Publication Date: 2016-12-20

Variant appearance in text: N/A
PubMed Link: 27829238
Variant Present in the following documents:
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The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate-Lactate Exchange in BRAF-Mutant Human Melanoma Cells.

Molecular Cancer Therapeutics
Delgado-Goni, Teresa T; Miniotis, Maria Falck MF; Wantuch, Slawomir S; Parkes, Harold G HG; Marais, Richard R; Workman, Paul P; Leach, Martin O MO; Beloueche-Babari, Mounia M
Publication Date: 2016-12

Variant appearance in text: N/A
PubMed Link: 27765851
Variant Present in the following documents:
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Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy.

Frontiers In Pharmacology
Belizário, José E JE; Sangiuliano, Beatriz A BA; Perez-Sosa, Marcela M; Neyra, Jennifer M JM; Moreira, Dayson F DF
Publication Date: 2016

Variant appearance in text: N/A
PubMed Link: 27746730
Variant Present in the following documents:
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An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.

Cancer Cell
Karoulia, Zoi Z; Wu, Yang Y; Ahmed, Tamer A TA; Xin, Qisheng Q; Bollard, Julien J; Krepler, Clemens C; Wu, Xuewei X; Zhang, Chao C; Bollag, Gideon G; Herlyn, Meenhard M; Fagin, James A JA; Lujambio, Amaia A; Gavathiotis, Evripidis E; Poulikakos, Poulikos I PI
Publication Date: 2016-09-12

Variant appearance in text: N/A
PubMed Link: 27523909
Variant Present in the following documents:
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miR-579-3p controls melanoma progression and resistance to target therapy.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Fattore, Luigi L; Mancini, Rita R; Acunzo, Mario M; Romano, Giulia G; Laganà, Alessandro A; Pisanu, Maria Elena ME; Malpicci, Debora D; Madonna, Gabriele G; Mallardo, Domenico D; Capone, Marilena M; Fulciniti, Franco F; Mazzucchelli, Luca L; Botti, Gerardo G; Croce, Carlo M CM; Ascierto, Paolo Antonio PA; Ciliberto, Gennaro G
Publication Date: 2016-08-23

Variant appearance in text: N/A
PubMed Link: 27503895
Variant Present in the following documents:
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Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015.

Journal Of Translational Medicine
Publication Date: 2016-07-25

Variant appearance in text: N/A
PubMed Link: 27461275
Variant Present in the following documents:
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The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.

Genome Medicine
Garofalo, Andrea A; Sholl, Lynette L; Reardon, Brendan B; Taylor-Weiner, Amaro A; Amin-Mansour, Ali A; Miao, Diana D; Liu, David D; Oliver, Nelly N; MacConaill, Laura L; Ducar, Matthew M; Rojas-Rudilla, Vanesa V; Giannakis, Marios M; Ghazani, Arezou A; Gray, Stacy S; Janne, Pasi P; Garber, Judy J; Joffe, Steve S; Lindeman, Neal N; Wagle, Nikhil N; Garraway, Levi A LA; Van Allen, Eliezer M EM
Publication Date: 2016-07-26

Variant appearance in text: rs121913377
PubMed Link: 27460824
Variant Present in the following documents:
  • 13073_2016_333_MOESM4_ESM.xlsx, sheet 1
  • 13073_2016_333_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation.

Oncotarget
Vallarelli, Andrelou F AF; Rachakonda, P Sivaramakrishna PS; André, Jocelyne J; Heidenreich, Barbara B; Riffaud, Laurence L; Bensussan, Armand A; Kumar, Rajiv R; Dumaz, Nicolas N
Publication Date: 2016-08-16

Variant appearance in text: N/A
PubMed Link: 27449293
Variant Present in the following documents:
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The evolution of combined molecular targeted therapies to advance the therapeutic efficacy in melanoma: a highlight of vemurafenib and cobimetinib.

Oncotargets And Therapy
Medina, Theresa M TM; Lewis, Karl D KD
Publication Date: 2016

Variant appearance in text: N/A
PubMed Link: 27382311
Variant Present in the following documents:
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RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma.

Oncotarget
Goedert, Lucas L; Pereira, Cristiano G CG; Roszik, Jason J; Plaça, Jessica R JR; Cardoso, Cibele C; Chen, Guo G; Deng, Wanleng W; Yennu-Nanda, Vashisht Gopal VG; Silva, Wilson A WA; Davies, Michael A MA; Espreafico, Enilza M EM
Publication Date: 2016-06-14

Variant appearance in text: N/A
PubMed Link: 27167340
Variant Present in the following documents:
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Histiocytic neoplasms in the era of personalized genomic medicine.

Current Opinion In Hematology
Durham, Benjamin H BH; Diamond, Eli L EL; Abdel-Wahab, Omar O
Publication Date: 2016-07

Variant appearance in text: N/A
PubMed Link: 27101528
Variant Present in the following documents:
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Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors.

Journal Of Translational Medicine
Schreuer, Max M; Meersseman, Geert G; Van Den Herrewegen, Sari S; Jansen, Yanina Y; Chevolet, Ines I; Bott, Ambre A; Wilgenhof, Sofie S; Seremet, Teofila T; Jacobs, Bart B; Buyl, Ronald R; Maertens, Geert G; Neyns, Bart B
Publication Date: 2016-04-19

Variant appearance in text: N/A
PubMed Link: 27095081
Variant Present in the following documents:
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BRAF V600 mutations in Langerhans cell histiocytosis with a simple and unique assay.

Diagnostic Pathology
Tatsuno, Michiko M; Shioda, Yoko Y; Iwafuchi, Hideto H; Yamazaki, Shigeki S; Iijima, Kenta K; Takahashi, Chiaki C; Ono, Hiromi H; Uchida, Kiyono K; Okamura, Osamu O; Matubayashi, Mamoru M; Okuyama, Torayuki T; Matsumoto, Kimikazu K; Yoshioka, Takako T; Nakazawa, Atsuko A
Publication Date: 2016-04-19

Variant appearance in text: N/A
PubMed Link: 27094161
Variant Present in the following documents:
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Managing leptomeningeal melanoma metastases in the era of immune and targeted therapy.

International Journal Of Cancer
Smalley, Keiran S M KS; Fedorenko, Inna V IV; Kenchappa, Rajappa S RS; Sahebjam, Solmaz S; Forsyth, Peter A PA
Publication Date: 2016-09-15

Variant appearance in text: N/A
PubMed Link: 27084046
Variant Present in the following documents:
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Long Term Survival and Continued Complete Response of Vemurafenib in a Metastatic Melanoma Patient with BRAF V600K Mutation.

Case Reports In Oncological Medicine
Sahadudheen, K K; Islam, Md Rafiqul MR; Iddawela, M M
Publication Date: 2016

Variant appearance in text: N/A
PubMed Link: 26989536
Variant Present in the following documents:
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BRAF-V600E expression in primary nodular melanoma is associated with aggressive tumour features and reduced survival.

British Journal Of Cancer
Hugdahl, Emilia E; Kalvenes, May Britt MB; Puntervoll, Hanne E HE; Ladstein, Rita G RG; Akslen, Lars A LA
Publication Date: 2016-03-29

Variant appearance in text: N/A
PubMed Link: 26924424
Variant Present in the following documents:
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Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.

Oncotarget
Eriksson, Johanna J; Le Joncour, Vadim V; Nummela, Pirjo P; Jahkola, Tiina T; Virolainen, Susanna S; Laakkonen, Pirjo P; Saksela, Olli O; Hölttä, Erkki E
Publication Date: 2016-03-22

Variant appearance in text: N/A
PubMed Link: 26918341
Variant Present in the following documents:
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Antitumor Activity of BRAF Inhibitor and IFNα Combination in BRAF-Mutant Melanoma.

Journal Of The National Cancer Institute
Sabbatino, Francesco F; Wang, Yangyang Y; Scognamiglio, Giosuè G; Favoino, Elvira E; Feldman, Steven A SA; Villani, Vincenzo V; Flaherty, Keith T KT; Nota, Sjoerd S; Giannarelli, Diana D; Simeone, Ester E; Anniciello, Anna M AM; Palmieri, Giuseppe G; Pepe, Stefano S; Botti, Gerardo G; Ascierto, Paolo A PA; Ferrone, Cristina R CR; Ferrone, Soldano S
Publication Date: 2016-07

Variant appearance in text: N/A
PubMed Link: 26851802
Variant Present in the following documents:
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The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.

Elife
Kiel, Christina C; Benisty, Hannah H; Lloréns-Rico, Veronica V; Serrano, Luis L
Publication Date: 2016-01-08

Variant appearance in text: N/A
PubMed Link: 26744778
Variant Present in the following documents:
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