Publications:

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Case Report: Rare Systemic and Aggressive ALK-Positive Histiocytosis With Recurrent Pancreatitis Treating by Alectinib.

Frontiers In Medicine

Li, Yanchu Y; Shi, Changle C; Wu, Yu Y; He, Mingmin M; Xia, Xueming X; Liu, Jie J; Jiang, Yu Y

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35665359

Variant Present in the following documents:

View BVdb publication page

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Patient-Derived Organoids of Colorectal Cancer: A Useful Tool for Personalized Medicine.

Journal Of Personalized Medicine

Kiwaki, Takumi T; Kataoka, Hiroaki H

Publication Date: 2022-04-26

Variant appearance in text: BRAF: V600K

PubMed Link: 35629118

Variant Present in the following documents:

• jpm-12-00695.pdf

View BVdb publication page

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Cancer stem cells, plasticity, and drug resistance.

Cancer Drug Resistance (Alhambra, Calif.)

Lionetti, Maria Chiara MC; Fumagalli, Maria Rita MR; La Porta, Caterina A M CAM

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 35582613

Variant Present in the following documents:

View BVdb publication page

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Drug resistance in targeted cancer therapies with RAF inhibitors.

Cancer Drug Resistance (Alhambra, Calif.)

Degirmenci, Ufuk U; Yap, Jiajun J; Sim, Yuen Rong M YRM; Qin, Shiru S; Hu, Jiancheng J

Publication Date: 2021

Variant appearance in text: N/A

PubMed Link: 35582307

Variant Present in the following documents:

View BVdb publication page

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Potential Biomarkers of Skin Melanoma Resistance to Targeted Therapy-Present State and Perspectives.

Cancers

Olbryt, Magdalena M

Publication Date: 2022-05-06

Variant appearance in text: N/A

PubMed Link: 35565444

Variant Present in the following documents:

View BVdb publication page

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Genetic and Clinical Characteristics of ARID1A Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival.

Cancers

Thielmann, Carl Maximilian CM; Matull, Johanna J; Roth, Sebastian S; Placke, Jan-Malte JM; Chorti, Eleftheria E; Zaremba, Anne A; Lodde, Georg G; Jansen, Philipp P; Krefting, Frederik F; Kretz, Julia J; Möller, Inga I; Sucker, Antje A; Paschen, Annette A; Livingstone, Elisabeth E; Zimmer, Lisa L; Ugurel, Selma S; Schadendorf, Dirk D; Hadaschik, Eva E; Griewank, Klaus G KG

Publication Date: 2022-04-22

Variant appearance in text: N/A

PubMed Link: 35565222

Variant Present in the following documents:

View BVdb publication page

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The Role of Treatment Sequencing with Immune-Checkpoint Inhibitors and BRAF/MEK Inhibitors for Response and Survival of Patients with BRAFV600-Mutant Metastatic Melanoma-A Retrospective, Real-World Cohort Study.

Cancers

Haist, Maximilian M; Stege, Henner H; Ebner, Ronja R; Fleischer, Maria Isabel MI; Loquai, Carmen C; Grabbe, Stephan S

Publication Date: 2022-04-21

Variant appearance in text: N/A

PubMed Link: 35565212

Variant Present in the following documents:

View BVdb publication page

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The Experiences of Patients With Adjuvant and Metastatic Melanoma Using Disease-Specific Social Media Communities in the Advent of Novel Therapies (Excite Project): Social Media Listening Study.

Jmir Cancer

Faust, Guy G; Booth, Alison A; Merinopoulou, Evie E; Halhol, Sonia S; Tosar, Heena H; Nawaz, Amir A; Szlachetka, Magdalena M; Chiu, Gavin G

Publication Date: 2022-05-13

Variant appearance in text: BRAF: V600K

PubMed Link: 35559986

Variant Present in the following documents:

• Main text

View BVdb publication page

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The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

Journal Of Translational Medicine

Ascierto, Paolo A PA; Warner, Allison Betof AB; Blank, Christian C; Caracò, Corrado C; Demaria, Sandra S; Gershenwald, Jeffrey E JE; Khushalani, Nikhil I NI; Long, Georgina V GV; Luke, Jason J JJ; Mehnert, Janice M JM; Robert, Caroline C; Rutkowski, Piotr P; Tawbi, Hussein A HA; Osman, Iman I; Puzanov, Igor I

Publication Date: 2022-05-10

Variant appearance in text: BRAF: V600K

PubMed Link: 35538491

Variant Present in the following documents:

• 12967_2022_Article_3406.pdf

View BVdb publication page

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Liquid biopsies to occult brain metastasis.

Molecular Cancer

Rehman, Asad Ur AU; Khan, Parvez P; Maurya, Shailendra Kumar SK; Siddiqui, Jawed A JA; Santamaria-Barria, Juan A JA; Batra, Surinder K SK; Nasser, Mohd Wasim MW

Publication Date: 2022-05-10

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35538484

Variant Present in the following documents:

• 12943_2022_Article_1577.pdf

View BVdb publication page

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Pediatric metanephric adenoma with Fanconi-Bickel syndrome: a case report and review of literature.

Surgical Case Reports

Sarhan, Osama M OM; Al Farhan, Ahmed A; Abdallah, Salma S; Al Ghwanmah, Hamzah H; Boqari, Deena D; Omar, Helmy H; Al Faddagh, Abdulmohsin A; Al Kanani, Hanan H; Al Kawai, Fouad F

Publication Date: 2022-05-05

Variant appearance in text: BRAF: V600K

PubMed Link: 35511306

Variant Present in the following documents:

• 40792_2022_Article_1435.pdf

View BVdb publication page

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Perspectives for Combining Viral Oncolysis With Additional Immunotherapies for the Treatment of Melanoma.

Frontiers In Molecular Biosciences

Cerqueira, Otto Luiz Dutra OLD; Antunes, Fernanda F; Assis, Nadine G NG; Cardoso, Elaine C EC; Clavijo-Salomón, Maria A MA; Domingues, Ana C AC; Tessarollo, Nayara G NG; Strauss, Bryan E BE

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35495634

Variant Present in the following documents:

• fmolb-09-777775.pdf

View BVdb publication page

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Anchored Multiplex PCR Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA.

Frontiers In Oncology

Diefenbach, Russell J RJ; Lee, Jenny H JH; Stewart, Ashleigh A; Menzies, Alexander M AM; Carlino, Matteo S MS; Saw, Robyn P M RPM; Stretch, Jonathan R JR; Long, Georgina V GV; Scolyer, Richard A RA; Rizos, Helen H

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35494035

Variant Present in the following documents:

• fonc-12-820510.pdf

View BVdb publication page

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Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy.

Science Advances

Ng, Thomas S C TSC; Hu, Huiyu H; Kronister, Stefan S; Lee, Chanseo C; Li, Ran R; Gerosa, Luca L; Stopka, Sylwia A SA; Burgenske, Danielle M DM; Khurana, Ishaan I; Regan, Michael S MS; Vallabhaneni, Sreeram S; Putta, Niharika N; Scott, Ella E; Matvey, Dylan D; Giobbie-Hurder, Anita A; Kohler, Rainer H RH; Sarkaria, Jann N JN; Parangi, Sareh S; Sorger, Peter K PK; Agar, Nathalie Y R NYR; Jacene, Heather A HA; Sullivan, Ryan J RJ; Buchbinder, Elizabeth E; Mikula, Hannes H; Weissleder, Ralph R; Miller, Miles A MA

Publication Date: 2022-04-29

Variant appearance in text: BRAF: V600K

PubMed Link: 35486732

Variant Present in the following documents:

• sciadv.abl6339_sm.pdf

View BVdb publication page

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A new solvate of clonixin and a comparison of the two clonixin solvates.

Rsc Advances

Zhoujin, Yunping Y; Zhang, Mingtao M; Parkin, Sean S; Li, Tonglei T; Yu, Faquan F; Long, Sihui S

Publication Date: 2021-07-13

Variant appearance in text: BRAF: V600K

PubMed Link: 35481021

Variant Present in the following documents:

• RA-011-D1RA03623H.pdf

View BVdb publication page

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In Vivo miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis.

Frontiers In Oncology

Moubarak, Rana S RS; Koetz-Ploch, Lisa L; Mullokandov, Gavriel G; Gaziel, Avital A; de Pablos-Aragoneses, Ana A; Argibay, Diana D; Kleffman, Kevin K; Sokolova, Elena E; Berwick, Marianne M; Thomas, Nancy E NE; Osman, Iman I; Brown, Brian D BD; Hernando, Eva E

Publication Date: 2022

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35480113

Variant Present in the following documents:

• fonc-12-852952.pdf

View BVdb publication page

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Low doses of niclosamide and quinacrine combination yields synergistic effect in melanoma via activating autophagy-mediated p53-dependent apoptosis.

Translational Oncology

Zheng, Xuan X; Zhang, Jianyun J; Li, Shuangting S; Gao, Xiaolei X; Zhang, Yixin Y; Wang, Meng M; Dong, Liying L; Sun, Liangjie L; Zhao, Na N; Ma, Zeyun Z; Ding, Chong C; Wang, Yixiang Y

Publication Date: 2022-04-20

Variant appearance in text: BRAF: V600K

PubMed Link: 35460941

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Successful Dabrafenib Desensitization Protocols in a Patient with Metastatic Melanoma.

Medicina (Kaunas, Lithuania)

Bumbacea, Roxana Silvia RS; Ali, Selda S; Corcea, Sabina Loredana SL; Jinga, Dan Corneliu DC; Spiru, Luiza L

Publication Date: 2022-04-03

Variant appearance in text: BRAF: V600k

PubMed Link: 35454350

Variant Present in the following documents:

• medicina-58-00511.pdf

View BVdb publication page

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Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

Plos One

Shi, Zonggao Z; Lopez, Jacqueline J; Kalliney, William W; Sutton, Bobbie B; Simpson, Joyce J; Maggert, Kevin K; Liu, Sheng S; Wan, Jun J; Stack, M Sharon MS

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35446881

Variant Present in the following documents:

• pone.0266914.pdf

View BVdb publication page

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Comprehensive Analysis of the Prognostic Signature of Mutation-Derived Genome Instability-Related lncRNAs for Patients With Endometrial Cancer.

Frontiers In Cell And Developmental Biology

Liu, Jinhui J; Cui, Guoliang G; Ye, Jun J; Wang, Yutong Y; Wang, Can C; Bai, Jianling J

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35433686

Variant Present in the following documents:

• fcell-10-753957.pdf

View BVdb publication page

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Case Report: Delayed Onset Multi-Organ Toxicities in a Melanoma Patient Achieving Complete Response to BRAF/MEK Inhibition.

Frontiers In Oncology

Knochelmann, Hannah M HM; Ware, Michael Brandon MB; Rali, Aditya A; Linderman, Susanne S; Shantha, Jessica G JG; Lawson, David H DH; Yushak, Melinda M; Swerlick, Robert R; Paulos, Chrystal M CM; Yeh, Steven S; Kudchadkar, Ragini R

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35433480

Variant Present in the following documents:

• fonc-12-836845.pdf

View BVdb publication page

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Phase I study of [131I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol.

Bmc Cancer

Thivat, Emilie E; Rouanet, Jacques J; Auzeloux, Philippe P; Sas, Nicolas N; Jouberton, Elodie E; Levesque, Sophie S; Billoux, Tommy T; Mansard, Sandrine S; Molnar, Ioana I; Chanchou, Marion M; Fois, Giovanna G; Maigne, Lydia L; Chezal, Jean-Michel JM; Miot-Noirault, Elisabeth E; D'Incan, Michel M; Durando, Xavier X; Cachin, Florent F

Publication Date: 2022-04-15

Variant appearance in text: BRAF: V600K

PubMed Link: 35428211

Variant Present in the following documents:

• 12885_2022_Article_9495.pdf

View BVdb publication page

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Heme Oxygenase-1 Has a Greater Effect on Melanoma Stem Cell Properties Than the Expression of Melanoma-Initiating Cell Markers.

International Journal Of Molecular Sciences

Kusienicka, Anna A; Bukowska-Strakova, Karolina K; Cieśla, Maciej M; Nowak, Witold Norbert WN; Bronisz-Budzyńska, Iwona I; Seretny, Agnieszka A; Żukowska, Monika M; Jeż, Mateusz M; Krutyhołowa, Rościsław R; Taha, Hevidar H; Kachamakova-Trojanowska, Neli N; Waś, Halina H; Kieda, Claudine C; Józkowicz, Alicja A

Publication Date: 2022-03-25

Variant appearance in text: BRAF: V600K

PubMed Link: 35408953

Variant Present in the following documents:

• ijms-23-03596.pdf

View BVdb publication page

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Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR.

International Journal Of Endocrinology

Lu, Sang-Yu SY; Chen, Ying-Chao YC; Feng, Jia-Lin JL; Zhou, Qin-Yi QY; Chen, Jing J; Zhu, Chen-Fang CF; Guo, Miao-Miao MM; Zhang, Man-Man MM; Zhang, Qian-Yue QY; Lu, Meng M; Yang, Liu L; Wu, Jing J; Zhao, Shuang-Xia SX; Song, Huai-Dong HD; Ye, Xiao-Ping XP

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35392249

Variant Present in the following documents:

View BVdb publication page

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Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation.

Journal For Immunotherapy Of Cancer

Wang, Minyu M; Zadeh, Soroor S; Pizzolla, Angela A; Thia, Kevin K; Gyorki, David E DE; McArthur, Grant A GA; Scolyer, Richard A RA; Long, Georgina G; Wilmott, James S JS; Andrews, Miles C MC; Au-Yeung, George G; Weppler, Ali A; Sandhu, Shahneen S; Trapani, Joseph A JA; Davis, Melissa J MJ; Neeson, Paul Joseph PJ

Publication Date: 2022-04

Variant appearance in text: N/A

PubMed Link: 35383113

Variant Present in the following documents:

View BVdb publication page

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Targeted Therapy for Melanomas Without BRAF V600 Mutations.

Current Treatment Options In Oncology

Menzer, Christian C; Hassel, Jessica C JC

Publication Date: 2022-04-05

Variant appearance in text: BRAF: V600K

PubMed Link: 35380338

Variant Present in the following documents:

• 11864_2022_Article_946.pdf

View BVdb publication page

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Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas.

Acta Neuropathologica Communications

Wolter, Marietta M; Felsberg, Jörg J; Malzkorn, Bastian B; Kaulich, Kerstin K; Reifenberger, Guido G

Publication Date: 2022-03-31

Variant appearance in text: BRAF: 1798_1799delinsAA

PubMed Link: 35361262

Variant Present in the following documents:

• 40478_2022_Article_1335.pdf
• 40478_2022_1335_MOESM1_ESM.pdf

View BVdb publication page

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Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib.

Cancer Biology & Therapy

Vigoda, Myles M; Mathieson, Chase C; Evans, Nathaniel N; Hale, Carolyn C; Jennings, Jennifer J; Lucero, Olivia O; Jeng, Sophia S; Bottomly, Daniel D; Clayburgh, Daniel D; Andersen, Peter P; Li, Ryan R; Petrisor, Daniel D; Tyner, Jeffrey W JW; McWeeney, Shannon S; Kulesz-Martin, Molly M

Publication Date: 2022-12-31

Variant appearance in text: N/A

PubMed Link: 35343367

Variant Present in the following documents:

View BVdb publication page

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CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer.

Molecular Cancer

Selvakumar, Sushmaa Chandralekha SC; Preethi, K Auxzilia KA; Ross, Kehinde K; Tusubira, Deusdedit D; Khan, Mohd Wajid Ali MWA; Mani, Panagal P; Rao, Tentu Nageswara TN; Sekar, Durairaj D

Publication Date: 2022-03-24

Variant appearance in text: N/A

PubMed Link: 35331236

Variant Present in the following documents:

View BVdb publication page

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Intracranial Metastatic Disease: Present Challenges, Future Opportunities.

Frontiers In Oncology

Li, Alyssa Y AY; Gaebe, Karolina K; Jerzak, Katarzyna J KJ; Cheema, Parneet K PK; Sahgal, Arjun A; Das, Sunit S

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35330715

Variant Present in the following documents:

View BVdb publication page

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Comparison of Two Rapid Assays for the Detection of BRAF V600 Mutations in Metastatic Melanoma including Positive Sentinel Lymph Nodes.

Diagnostics (Basel, Switzerland)

Long-Mira, Elodie E; Picard-Gauci, Alexandra A; Lassalle, Sandra S; Hofman, Véronique V; Lalvée, Salomé S; Tanga, Virginie V; Zahaf, Katia K; Bonnetaud, Christelle C; Lespinet, Virginie V; Camuzard, Olivier O; Montaudié, Henri H; Poissonnet, Gilles G; Passeron, Thierry T; Ilié, Marius M; Hofman, Paul P

Publication Date: 2022-03-19

Variant appearance in text: N/A

PubMed Link: 35328303

Variant Present in the following documents:

View BVdb publication page

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Liquid Profiling for Cancer Patient Stratification in Precision Medicine-Current Status and Challenges for Successful Implementation in Standard Care.

Diagnostics (Basel, Switzerland)

Haselmann, Verena V; Hedtke, Maren M; Neumaier, Michael M

Publication Date: 2022-03-19

Variant appearance in text: N/A

PubMed Link: 35328301

Variant Present in the following documents:

View BVdb publication page

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A Case of Non-Irradiated Balloon Cell Melanoma of the Choroid: Expanding the Morphological Spectrum of Primary Uveal Melanomas.

Diagnostics (Basel, Switzerland)

Failla, Maria M; Caltabiano, Rosario R; Longo, Antonio A; Russo, Andrea A; Reibaldi, Michele M; Avitabile, Teresio T; Piombino, Eliana E; Colarossi, Cristina C; Colarossi, Lorenzo L; Tirrò, Elena E; Vigneri, Paolo P; Foti, Pietro Valerio PV; Broggi, Giuseppe G

Publication Date: 2022-03-05

Variant appearance in text: N/A

PubMed Link: 35328195

Variant Present in the following documents:

View BVdb publication page

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Immune Landscape and an RBM38-Associated Immune Prognostic Model with Laboratory Verification in Malignant Melanoma.

Cancers

Liu, Jinfang J; Xu, Jun J; Luo, Binlin B; Tang, Jian J; Hou, Zuoqiong Z; Zhu, Zhechen Z; Zhu, Lingjun L; Yao, Gang G; Li, Chujun C

Publication Date: 2022-03-21

Variant appearance in text: N/A

PubMed Link: 35326741

Variant Present in the following documents:

View BVdb publication page

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The Prognostic Value of miR-125b, miR-200c and miR-205 in Primary Cutaneous Malignant Melanoma Is Independent of BRAF Mutational Status.

Cancers

Sánchez-Sendra, Beatriz B; González-Muñoz, José F JF; Pérez-Debén, Silvia S; Monteagudo, Carlos C

Publication Date: 2022-03-16

Variant appearance in text: N/A

PubMed Link: 35326682

Variant Present in the following documents:

View BVdb publication page

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Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

Plos One

Williams, Gareth G; Llewelyn, Alexander A; Thatcher, Robert R; Hardisty, Keeda-Marie KM; Loddo, Marco M

Publication Date: 2022

Variant appearance in text: rs121913227

PubMed Link: 35324914

Variant Present in the following documents:

• pone.0245817.s005.pdf

View BVdb publication page

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Point of Care Molecular Testing: Community-Based Rapid Next-Generation Sequencing to Support Cancer Care.

Current Oncology (Toronto, Ont.)

Sheffield, Brandon S BS; Beharry, Andrea A; Diep, Joanne J; Perdrizet, Kirstin K; Iafolla, Marco A J MAJ; Raskin, William W; Dudani, Shaan S; Brett, Mary Anne MA; Starova, Blerta B; Olsen, Brian B; Cheema, Parneet K PK

Publication Date: 2022-02-23

Variant appearance in text: N/A

PubMed Link: 35323313

Variant Present in the following documents:

View BVdb publication page

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Improving Brain Metastases Outcomes Through Therapeutic Synergy Between Stereotactic Radiosurgery and Targeted Cancer Therapies.

Frontiers In Oncology

Rubino, Sebastian S; Oliver, Daniel E DE; Tran, Nam D ND; Vogelbaum, Michael A MA; Forsyth, Peter A PA; Yu, Hsiang-Hsuan Michael HM; Ahmed, Kamran K; Etame, Arnold B AB

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35311078

Variant Present in the following documents:

View BVdb publication page

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Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors.

Plos One

Milbury, Coren A CA; Creeden, James J; Yip, Wai-Ki WK; Smith, David L DL; Pattani, Varun V; Maxwell, Kristi K; Sawchyn, Bethany B; Gjoerup, Ole O; Meng, Wei W; Skoletsky, Joel J; Concepcion, Alvin D AD; Tang, Yanhua Y; Bai, Xiaobo X; Dewal, Ninad N; Ma, Pei P; Bailey, Shannon T ST; Thornton, James J; Pavlick, Dean C DC; Frampton, Garrett M GM; Lieber, Daniel D; White, Jared J; Burns, Christine C; Vietz, Christine C

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35294956

Variant Present in the following documents:

View BVdb publication page

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Cancer Drug Approvals That Displaced Existing Standard-of-Care Therapies, 2016-2021.

Jama Network Open

Benjamin, David J DJ; Xu, Alexander A; Lythgoe, Mark P MP; Prasad, Vinay V

Publication Date: 2022-03-01

Variant appearance in text: N/A

PubMed Link: 35289858

Variant Present in the following documents:

View BVdb publication page

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Anaplastic thyroid cancer: genome-based search for new targeted therapy options.

Endocrine Connections

Hescheler, Daniel Alexander DA; Hartmann, Milan Janis Michael MJM; Riemann, Burkhard B; Michel, Maximilian M; Bruns, Christiane Josephine CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2022-03-01

Variant appearance in text: BRAF: V600K

PubMed Link: 35275096

Variant Present in the following documents:

• supplementary_table_1.xlsx

View BVdb publication page

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Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties.

Journal Of Translational Medicine

Audrito, Valentina V; Moiso, Enrico E; Ugolini, Filippo F; Messana, Vincenzo Gianluca VG; Brandimarte, Lorenzo L; Manfredonia, Ilaria I; Bianchi, Simonetta S; De Logu, Francesco F; Nassini, Romina R; Szumera-Ciećkiewicz, Anna A; Taverna, Daniela D; Massi, Daniela D; Deaglio, Silvia S

Publication Date: 2022-03-10

Variant appearance in text: N/A

PubMed Link: 35272691

Variant Present in the following documents:

View BVdb publication page

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An integrative gene expression signature analysis identifies CMS4 KRAS-mutated colorectal cancers sensitive to combined MEK and SRC targeted therapy.

Bmc Cancer

Yang, Mingli M; Davis, Thomas B TB; Pflieger, Lance L; Nebozhyn, Michael V MV; Loboda, Andrey A; Wang, Heiman H; Schell, Michael J MJ; Thota, Ramya R; Pledger, W Jack WJ; Yeatman, Timothy J TJ

Publication Date: 2022-03-10

Variant appearance in text: N/A

PubMed Link: 35272617

Variant Present in the following documents:

View BVdb publication page

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A radiologist's guide to novel anticancer therapies in the era of precision medicine.

European Journal Of Radiology Open

Khader, Ali A; Bokhari, Rozan R; Hakimelahi, Reza R; Scheirey, Christopher C; Afnan, Jalil J; Braschi-Amirfarzan, Marta M; Thomas, Richard R

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35265736

Variant Present in the following documents:

View BVdb publication page

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Detection of CCR5Δ32 Mutant Alleles in Heterogeneous Cell Mixtures Using Droplet Digital PCR.

Frontiers In Molecular Biosciences

Sorokina, Alyona A; Artyuhov, Alexander A; Goltsova, Alexandra A; Dashinimaev, Erdem E

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35265670

Variant Present in the following documents:

View BVdb publication page

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T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.

Frontiers In Immunology

Torres, Gretel M GM; Yang, Heetaek H; Park, Chanhyuk C; Spezza, Paul A PA; Khatwani, Nikhil N; Bhandari, Rajan R; Liby, Karen T KT; Pioli, Patricia A PA

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35265066

Variant Present in the following documents:

View BVdb publication page

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Portable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples.

Scientific Reports

Papadakis, G G; Pantazis, A K AK; Fikas, N N; Chatziioannidou, S S; Tsiakalou, V V; Michaelidou, K K; Pogka, V V; Megariti, M M; Vardaki, M M; Giarentis, K K; Heaney, J J; Nastouli, E E; Karamitros, T T; Mentis, A A; Zafiropoulos, A A; Sourvinos, G G; Agelaki, S S; Gizeli, E E

Publication Date: 2022-03-08

Variant appearance in text: N/A

PubMed Link: 35260588

Variant Present in the following documents:

View BVdb publication page

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Melanoma therapeutics: a literature review.

Journal Of Biomedical Research

Dhanyamraju, Pavan Kumar PK; Patel, Trupti N TN

Publication Date: 2022-02-28

Variant appearance in text: N/A

PubMed Link: 35260531

Variant Present in the following documents:

View BVdb publication page

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SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases (2021).

Clinical & Translational Oncology : Official Publication Of The Federation Of Spanish Oncology Societies And Of The National Cancer Institute Of Mexico

Martínez-García, María M; Servitja Tormo, Sonia S; Vilariño Quintela, Noelia N; Arance Fernández, Ana A; Berrocal Jaime, Alfonso A; Cantos Sánchez de Ibargüen, Blanca B; Del Barco Berrón, Sonia S; García Campelo, Rosario R; Gironés Sarrió, Regina R; Manuel Sepúlveda-Sánchez, Juan J

Publication Date: 2022-03-08

Variant appearance in text: N/A

PubMed Link: 35258806

Variant Present in the following documents:

View BVdb publication page

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Neoadjuvant therapy for melanoma: rationale for neoadjuvant therapy and pivotal clinical trials.

Therapeutic Advances In Medical Oncology

Witt, Russell G RG; Erstad, Derek J DJ; Wargo, Jennifer A JA

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35251322

Variant Present in the following documents:

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Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma.

Nature Communications

Smith, Lorey K LK; Parmenter, Tiffany T; Kleinschmidt, Margarete M; Kusnadi, Eric P EP; Kang, Jian J; Martin, Claire A CA; Lau, Peter P; Patel, Riyaben R; Lorent, Julie J; Papadopoli, David D; Trigos, Anna A; Ward, Teresa T; Rao, Aparna D AD; Lelliott, Emily J EJ; Sheppard, Karen E KE; Goode, David D; Hicks, Rodney J RJ; Tiganis, Tony T; Simpson, Kaylene J KJ; Larsson, Ola O; Blythe, Benjamin B; Cullinane, Carleen C; Wickramasinghe, Vihandha O VO; Pearson, Richard B RB; McArthur, Grant A GA

Publication Date: 2022-03-01

Variant appearance in text: N/A

PubMed Link: 35232962

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: N/A

PubMed Link: 35221333

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Not so 'rare'-an example of malignant melanoma in India: report from a tertiary cancer centre.

Ecancermedicalscience

Biswas, Bivas B; Biswas, Gautam G; Ganguly, Sandip S; Ghosh, Joydeep J; Roy, Somnath S; Roy, Manas Kumar MK; Pipara, Amrit A; Karmakar, Jagriti J; Mukherjee, Navonil N; Chakraborty, Santam S; Mishra, Deepak Kumar DK; Midha, Divya D; Dabkara, Deepak D

Publication Date: 2021

Variant appearance in text: N/A

PubMed Link: 35211204

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Recent Developments of Circulating Tumor Cell Analysis for Monitoring Cutaneous Melanoma Patients.

Cancers

Shoji, Yoshiaki Y; Bustos, Matias A MA; Gross, Rebecca R; Hoon, Dave S B DSB

Publication Date: 2022-02-09

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35205608

Variant Present in the following documents:

• cancers-14-00859.pdf

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Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach.

Genes

Venkatraman, Simran S; Balasubramanian, Brinda B; Pongchaikul, Pisut P; Tohtong, Rutaiwan R; Chutipongtanate, Somchai S

Publication Date: 2022-01-29

Variant appearance in text: BRAF: V600K

PubMed Link: 35205315

Variant Present in the following documents:

• genes-13-00271.pdf

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Metanephric adenoma: molecular study and review of the literature.

Oncotarget

Rodríguez-Zarco, Enrique E; Machuca-Aguado, Jesús J; Macías-García, Laura L; Vallejo-Benítez, Ana A; Ríos-Martín, Juan José JJ

Publication Date: 2022

Variant appearance in text: BRAF: V600K

PubMed Link: 35198098

Variant Present in the following documents:

• oncotarget-13-28192.pdf

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Correlation between treatment effects on response rate and progression-free survival and overall survival in trials of targeted therapies in molecularly enriched populations.

Esmo Open

Solomon, B J BJ; Loong, H H HH; Summers, Y Y; Thomas, Z M ZM; French, P P; Lin, B K BK; Sashegyi, A A; Wolf, J J; Yang, J C-H JC; Drilon, A A

Publication Date: 2022-02-15

Variant appearance in text: BRAF: V600K

PubMed Link: 35183043

Variant Present in the following documents:

• main.pdf

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Ultrarapid lytic granule release from CTLs activates Ca2+-dependent synaptic resistance pathways in melanoma cells.

Science Advances

Filali, Liza L; Puissegur, Marie-Pierre MP; Cortacero, Kevin K; Cussat-Blanc, Sylvain S; Khazen, Roxana R; Van Acker, Nathalie N; Frenois, François-Xavier FX; Abreu, Arnaud A; Lamant, Laurence L; Meyer, Nicolas N; Vergier, Béatrice B; Müller, Sabina S; McKenzie, Brienne B; Valitutti, Salvatore S

Publication Date: 2022-02-18

Variant appearance in text: BRAF: V600K

PubMed Link: 35171665

Variant Present in the following documents:

• sciadv.abk3234_sm.pdf

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New Therapeutic Approaches for Conjunctival Melanoma-What We Know So Far and Where Therapy Is Potentially Heading: Focus on Lymphatic Vessels and Dendritic Cells.

International Journal Of Molecular Sciences

Peil, Jennifer J; Bock, Felix F; Kiefer, Friedemann F; Schmidt, Rebecca R; Heindl, Ludwig M LM; Cursiefen, Claus C; Schlereth, Simona L SL

Publication Date: 2022-01-27

Variant appearance in text: BRAF: V600K

PubMed Link: 35163401

Variant Present in the following documents:

• Main text
• ijms-23-01478.pdf

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Current Controversies and Challenges on BRAF V600K-Mutant Cutaneous Melanoma.

Journal Of Clinical Medicine

Nepote, Alessandro A; Avallone, Gianluca G; Ribero, Simone S; Cavallo, Francesco F; Roccuzzo, Gabriele G; Mastorino, Luca L; Conforti, Claudio C; Paruzzo, Luca L; Poletto, Stefano S; Carnevale Schianca, Fabrizio F; Quaglino, Pietro P; Aglietta, Massimo M

Publication Date: 2022-02-04

Variant appearance in text: BRAF: V600K

PubMed Link: 35160279

Variant Present in the following documents:

• Main text
• jcm-11-00828.pdf

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Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process.

Cells

Melixetian, Marine M; Pelicci, Pier Giuseppe PG; Lanfrancone, Luisa L

Publication Date: 2022-02-07

Variant appearance in text: BRAF: V600K

PubMed Link: 35159386

Variant Present in the following documents:

• Main text
• cells-11-00577.pdf

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The Use of ctDNA for BRAF Mutation Testing in Routine Clinical Practice in Patients with Advanced Melanoma.

Cancers

Sobczuk, Paweł P; Kozak, Katarzyna K; Kopeć, Sylwia S; Rogala, Paweł P; Świtaj, Tomasz T; Koseła-Paterczyk, Hanna H; Gos, Aleksandra A; Tysarowski, Andrzej A; Rutkowski, Piotr P

Publication Date: 2022-02-02

Variant appearance in text: BRAF: V600K

PubMed Link: 35159044

Variant Present in the following documents:

• Main text
• cancers-14-00777.pdf

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New Approaches with Precision Medicine in Adult Brain Tumors.

Cancers

Leibetseder, Annette A; Preusser, Matthias M; Berghoff, Anna Sophie AS

Publication Date: 2022-01-29

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35158978

Variant Present in the following documents:

• cancers-14-00712.pdf

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Plant-Derived Terpenoids: A Promising Tool in the Fight against Melanoma.

Cancers

Kłos, Patrycja P; Chlubek, Dariusz D

Publication Date: 2022-01-20

Variant appearance in text: BRAF: V600K

PubMed Link: 35158770

Variant Present in the following documents:

• Main text
• cancers-14-00502.pdf

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Dramatic Therapeutic Response to Dabrafenib Plus Trametinib in BRAF V600E Mutated Papillary Craniopharyngiomas: A Case Report and Literature Review.

Frontiers In Medicine

Fasano, Morena M; Della Corte, Carminia Maria CM; Caterino, Marianna M; Pirozzi, Mario M; Rauso, Raffaele R; Troiani, Teresa T; Martini, Giulia G; Napolitano, Stefania S; Morgillo, Floriana F; Ciardiello, Fortunato F

Publication Date: 2021

Variant appearance in text: BRAF: V600K

PubMed Link: 35155453

Variant Present in the following documents:

• fmed-08-652005.pdf

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Vemurafenib Combined With Trametinib Significantly Benefits the Survival of a Patient With Stage IV Pancreatic Ductal Adenocarcinoma With BRAF V600E Mutation: A Case Report.

Frontiers In Oncology

Wang, Ziyao Z; He, Du D; Chen, Chen C; Liu, Xubao X; Ke, Nengwen N

Publication Date: 2021

Variant appearance in text: BRAF: V600k

PubMed Link: 35145907

Variant Present in the following documents:

• fonc-11-801320.pdf

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Circulating Tumour DNA in Melanoma-Clinic Ready?

Current Oncology Reports

Tivey, Ann A; Britton, Fiona F; Scott, Julie-Ann JA; Rothwell, Dominic D; Lorigan, Paul P; Lee, Rebecca R

Publication Date: 2022-02-08

Variant appearance in text: BRAF: V600K

PubMed Link: 35133615

Variant Present in the following documents:

• 11912_2021_Article_1151.pdf

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.

Journal Of Experimental & Clinical Cancer Research : Cr

Voon, Pei Jye PJ; Chen, Eric X EX; Chen, Helen X HX; Lockhart, Albert C AC; Sahebjam, Solmaz S; Kelly, Karen K; Vaishampayan, Ulka N UN; Subbiah, Vivek V; Razak, Albiruni R AR; Renouf, Daniel J DJ; Hotte, Sebastien J SJ; Singh, Arti A; Bedard, Philippe L PL; Hansen, Aaron R AR; Ivy, S Percy SP; Wang, Lisa L; Stayner, Lee-Anne LA; Siu, Lillian L LL; Spreafico, Anna A

Publication Date: 2022-02-07

Variant appearance in text: BRAF: V600K

PubMed Link: 35130943

Variant Present in the following documents:

• Main text
• 13046_2021_Article_2236.pdf
• 13046_2021_2236_MOESM3_ESM.pdf

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Proteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors.

Acs Omega

Martinez, Ramon R; Huang, Weiliang W; Buck, Heather H; Rea, Samantha S; Defnet, Amy E AE; Kane, Maureen A MA; Shapiro, Paul P

Publication Date: 2022-02-01

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35128241

Variant Present in the following documents:

• ao1c05361.pdf

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Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial.

Lancet (London, England)

Gershenson, David M DM; Miller, Austin A; Brady, William E WE; Paul, James J; Carty, Karen K; Rodgers, William W; Millan, David D; Coleman, Robert L RL; Moore, Kathleen N KN; Banerjee, Susana S; Connolly, Kate K; Secord, Angeles Alvarez AA; O'Malley, David M DM; Dorigo, Oliver O; Gaillard, Stephanie S; Gabra, Hani H; Slomovitz, Brian B; Hanjani, Parviz P; Farley, John J; Churchman, Michael M; Ewing, Ailith A; Hollis, Robert L RL; Herrington, C Simon CS; Huang, Helen Q HQ; Wenzel, Lari L; Gourley, Charlie C

Publication Date: 2022-02-05

Variant appearance in text: BRAF: Val600Lys

PubMed Link: 35123694

Variant Present in the following documents:

• Main text
• mmc1.pdf
• main.pdf

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Mutational profiling of melanomas in patients from the southeast coast of China.

Translational Cancer Research

Zheng, Ai-Wen AW; Jia, Dong-Dong DD; Zhou, Cheng-Cheng CC; Li, Tao T

Publication Date: 2020-08

Variant appearance in text: BRAF: V600K

PubMed Link: 35117841

Variant Present in the following documents:

• Main text
• tcr-09-08-4781.pdf

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A pan-cancer study of PD-1 and CTLA-4 as therapeutic targets.

Translational Cancer Research

Cai, Zongqiang Z; Ang, Xiaojie X; Xu, Zekun Z; Li, Shiqing S; Zhang, Jianglei J; Pei, Changsong C; Zhou, Feng F

Publication Date: 2021-09

Variant appearance in text: BRAF: V600K

PubMed Link: 35116697

Variant Present in the following documents:

• Main text
• tcr-10-09-3993.pdf

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The Future of Precision Prevention for Advanced Melanoma.

Frontiers In Medicine

Lee, Katie J KJ; Betz-Stablein, Brigid B; Stark, Mitchell S MS; Janda, Monika M; McInerney-Leo, Aideen M AM; Caffery, Liam J LJ; Gillespie, Nicole N; Yanes, Tatiane T; Soyer, H Peter HP

Publication Date: 2021

Variant appearance in text: BRAF: V600K

PubMed Link: 35111789

Variant Present in the following documents:

• fmed-08-818096.pdf

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Rapidly Changing Serous Detachment During BRAF and MEK Inhibitor Therapy.

Cureus

Agata, Chisato C; Kitamoto, Kohdai K; Ueda, Kohei K; Azuma, Keiko K; Inoue, Tatsuya T; Obata, Ryo R

Publication Date: 2021-12

Variant appearance in text: BRAF: V600K

PubMed Link: 35070538

Variant Present in the following documents:

• Main text
• cureus-0013-00000020491.pdf

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Enrichment of SOX2-Positive Cells in BRAF V600E Mutated and Recurrent Ameloblastoma.

Journal Of Personalized Medicine

Tseng, Chih-Huang CH; Lu, Pei-Hsuan PH; Wang, Yi-Ping YP; Chang, Julia Yu Fong JYF

Publication Date: 2022-01-08

Variant appearance in text: BRAF: v600k

PubMed Link: 35055392

Variant Present in the following documents:

• jpm-12-00077.pdf

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Nuclear Localization of BRAFV600E Is Associated with HMOX-1 Upregulation and Aggressive Behavior of Melanoma Cells.

Cancers

Zerfaoui, Mourad M; Toraih, Eman E; Ruiz, Emmanuelle E; Errami, Youssef Y; Attia, Abdallah S AS; Krzysztof, Moroz M; Abd Elmageed, Zakaria Y ZY; Kandil, Emad E

Publication Date: 2022-01-09

Variant appearance in text: BRAF: V600K

PubMed Link: 35053476

Variant Present in the following documents:

• cancers-14-00311.pdf

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Oral Cancer Stem Cells: Therapeutic Implications and Challenges.

Frontiers In Oral Health

Shahoumi, Linah A LA

Publication Date: 2021

Variant appearance in text: BRAF: V600K

PubMed Link: 35048028

Variant Present in the following documents:

• Main text
• froh-02-685236.pdf

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A B-Raf V600E gene signature for melanoma predicts prognosis and reveals sensitivity to targeted therapies.

Cancer Medicine

Yao, Kevin K; Zhou, Emily E; Cheng, Chao C

Publication Date: 2022-01-19

Variant appearance in text: BRAF: V600K

PubMed Link: 35044091

Variant Present in the following documents:

• CAM4-11-1232.pdf

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Randomized Phase III Trial Evaluating Spartalizumab Plus Dabrafenib and Trametinib for BRAF V600-Mutant Unresectable or Metastatic Melanoma.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

Dummer, Reinhard R; Long, Georgina V GV; Robert, Caroline C; Tawbi, Hussein A HA; Flaherty, Keith T KT; Ascierto, Paolo A PA; Nathan, Paul D PD; Rutkowski, Piotr P; Leonov, Oleg O; Dutriaux, Caroline C; Mandalà, Mario M; Lorigan, Paul P; Ferrucci, Pier Francesco PF; Grob, Jean Jacques JJ; Meyer, Nicolas N; Gogas, Helen H; Stroyakovskiy, Daniil D; Arance, Ana A; Brase, Jan C JC; Green, Steven S; Haas, Tomas T; Masood, Aisha A; Gasal, Eduard E; Ribas, Antoni A; Schadendorf, Dirk D

Publication Date: 2022-01-14

Variant appearance in text: BRAF: V600K

PubMed Link: 35030011

Variant Present in the following documents:

• jco-40-1428.pdf

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Dabrafenib- and trametinib-associated glomerular toxicity: A case report.

Medicine

Jo, Eunmi E; Rhee, Harin H

Publication Date: 2022-01-07

Variant appearance in text: BRAF: V600K

PubMed Link: 35029901

Variant Present in the following documents:

• Main text
• medi-101-e28485.pdf

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