BRAF c.1798_1799delinsAA ;(p.V600K)

Variant ID: 7-140453136-AC-TT

NM_004333.4(BRAF):c.1798_1799delinsAA;(p.V600K)

This variant was identified in 1394 publications

View GRCh38 version.




Publications:


Dabrafenib-Panobinostat Salt: Improving the Dissolution Rate and Inhibition of BRAF Melanoma Cells.

Acs Omega
Rai, Sunil K SK; Marverti, Gaetano G; Gunnam, Anilkumar A; Allu, Suryanarayana S; Nangia, Ashwini K AK
Publication Date: 2023-05-23

Variant appearance in text: BRAF: V600K
PubMed Link: 37251170
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Genomic Landscape of Melanoma and Its Therapeutic Implications.

Genes
Yang, Ting-Ting TT; Yu, Sebastian S; Ke, Chiao-Li Khale CK; Cheng, Shih-Tsung ST
Publication Date: 2023-04-29

Variant appearance in text: BRAF: V600K
PubMed Link: 37239381
Variant Present in the following documents:
  • Main text
  • genes-14-01021.pdf
View BVdb publication page



TME-targeted approaches of brain metastases and its clinical therapeutic evidence.

Frontiers In Immunology
Khan, Ibrar Muhammad IM; Khan, Safir Ullah SU; Sala, Hari Siva Sai HSS; Khan, Munir Ullah MU; Ud Din, Muhammad Azhar MA; Khan, Samiullah S; Hassan, Syed Shams Ul SSU; Khan, Nazir Muhammad NM; Liu, Yong Y
Publication Date: 2023

Variant appearance in text: BRAF: Val600Lys
PubMed Link: 37228619
Variant Present in the following documents:
  • fimmu-14-1131874.pdf
View BVdb publication page



BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current Knowledge.

Cancers
Florent, Laetitia L; Saby, Charles C; Slimano, Florian F; Morjani, Hamid H
Publication Date: 2023-05-04

Variant appearance in text: BRAF: V600K
PubMed Link: 37174072
Variant Present in the following documents:
  • Main text
  • cancers-15-02607.pdf
View BVdb publication page



Talimogene laherparepvec in combination with ipilimumab versus ipilimumab alone for advanced melanoma: 5-year final analysis of a multicenter, randomized, open-label, phase II trial.

Journal For Immunotherapy Of Cancer
Chesney, Jason A JA; Puzanov, Igor I; Collichio, Frances A FA; Singh, Parminder P; Milhem, Mohammed M MM; Glaspy, John J; Hamid, Omid O; Ross, Merrick M; Friedlander, Philip P; Garbe, Claus C; Logan, Theodore T; Hauschild, Axel A; Lebbé, Celeste C; Joshi, Harshada H; Snyder, Wendy W; Mehnert, Janice M JM
Publication Date: 2023-05

Variant appearance in text: BRAF: V600K
PubMed Link: 37142291
Variant Present in the following documents:
  • jitc-2022-006270supp002.pdf
View BVdb publication page



Liquid-liquid phase separation throws novel insights into treatment strategies for skin cutaneous melanoma.

Bmc Cancer
Liu, Jianlan J; Pei, Shengbin S; Zhang, Pengpeng P; Jiang, Keyu K; Luo, Binlin B; Hou, Zuoqiong Z; Yao, Gang G; Tang, Jian J
Publication Date: 2023-05-01

Variant appearance in text: BRAF: V600K
PubMed Link: 37127623
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10847.pdf
View BVdb publication page



BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience.

Frontiers In Oncology
Trinder, Sarah M SM; McKay, Campbell C; Power, Phoebe P; Topp, Monique M; Chan, Bosco B; Valvi, Santosh S; McCowage, Geoffrey G; Govender, Dinisha D; Kirby, Maria M; Ziegler, David S DS; Manoharan, Neevika N; Hassall, Tim T; Kellie, Stewart S; Heath, John J; Alvaro, Frank F; Wood, Paul P; Laughton, Stephen S; Tsui, Karen K; Dodgshun, Andrew A; Eisenstat, David D DD; Endersby, Raelene R; Luen, Stephen J SJ; Koh, Eng-Siew ES; Sim, Hao-Wen HW; Kong, Benjamin B; Gottardo, Nicholas G NG; Whittle, James R JR; Khuong-Quang, Dong-Anh DA; Hansford, Jordan R JR
Publication Date: 2023

Variant appearance in text: BRAF: V600K
PubMed Link: 37124503
Variant Present in the following documents:
  • Main text
  • fonc-13-1154246.pdf
View BVdb publication page



Brief Communication on Pathologic Assessment of Persistent Stable Metastatic Lesions in Patients Treated With Anti-CTLA-4 or Anti-CTLA-4 + Anti-PD-1 Therapy.

Journal Of Immunotherapy (Hagerstown, Md. : 1997)
Buchbinder, Elizabeth I EI; Pfaff, Kathleen L KL; Turner, Madison M MM; Manos, Michael M; Ouyang, Olivia O; Ott, Patrick A PA; Giobbie-Hurder, Anita A; Rodig, Scott J SJ; Hodi, F Stephen FS
Publication Date: 2023-05-01

Variant appearance in text: BRAF: V600K
PubMed Link: 37115942
Variant Present in the following documents:
  • Main text
  • cji-46-192.pdf
View BVdb publication page



Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy.

Molecular Diagnosis & Therapy
Fitzgerald, Sandra S; Blenkiron, Cherie C; Stephens, Rosalie R; Mathy, Jon A JA; Somers-Edgar, Tiffany T; Rolfe, Gill G; Martin, Richard R; Jackson, Christopher C; Eccles, Michael M; Robb, Tamsin T; Rodger, Euan E; Lawrence, Ben B; Guilford, Parry P; Lasham, Annette A; Print, Cristin G CG
Publication Date: 2023-04-26

Variant appearance in text: BRAF: V600K
PubMed Link: 37099071
Variant Present in the following documents:
  • Main text
  • 40291_2023_651_MOESM15_ESM.pdf
  • 40291_2023_651_MOESM8_ESM.pdf
  • 40291_2023_651_MOESM9_ESM.pdf
  • 40291_2023_651_MOESM3_ESM.pdf
  • 40291_2023_651_MOESM5_ESM.pdf
  • 40291_2023_651_MOESM1_ESM.xlsx, sheet 9
  • 40291_2023_Article_651.pdf
  • 40291_2023_651_MOESM1_ESM.xlsx, sheet 6
  • 40291_2023_651_MOESM4_ESM.pdf
  • 40291_2023_651_MOESM1_ESM.xlsx, sheet 8
View BVdb publication page



A Complex of Pyrosequencing-Based Methods for Detection of Somatic Mutations in Codons 600 and 601 of the BRAF gene.

Sovremennye Tekhnologii V Meditsine
Dribnokhodova, O P OP; Esman, A S AS; Korchagin, V I VI; Bukharina, A Yu AY; Dunaeva, E A EA; Leshkina, G V GV; Borisova, E V EV; Voiciehovskaya, Ya A YA; Daoud, A I AI; Khlyavich, V N VN; Mironov, K O KO
Publication Date: 2022

Variant appearance in text: BRAF: 1798_1799delinsAA
PubMed Link: 37065428
Variant Present in the following documents:
  • Main text
  • STM-14-2-04.pdf
View BVdb publication page



Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial.

Nature Medicine
Subbiah, Vivek V; Kreitman, Robert J RJ; Wainberg, Zev A ZA; Gazzah, Anas A; Lassen, Ulrik U; Stein, Alexander A; Wen, Patrick Y PY; Dietrich, Sascha S; de Jonge, Maja J A MJA; Blay, Jean-Yves JY; Italiano, Antoine A; Yonemori, Kan K; Cho, Daniel C DC; de Vos, Filip Y F L FYFL; Moreau, Philippe P; Fernandez, Elena Elez EE; Schellens, Jan H M JHM; Zielinski, Christoph C CC; Redhu, Suman S; Boran, Aislyn A; Passos, Vanessa Q VQ; Ilankumaran, Palanichamy P; Bang, Yung-Jue YJ
Publication Date: 2023-04-14

Variant appearance in text: BRAF: V600K
PubMed Link: 37059834
Variant Present in the following documents:
  • 41591_2023_2321_MOESM1_ESM.pdf
View BVdb publication page



Relapse of Non-Gastrointestinal Langerhans Cell Histiocytosis in the Rectum in a Child: A Case Report.

Clinical Medicine Insights. Case Reports
Saeed, Saad Muhammad SM; Bilal, Sundus S; Loya, Asif A; Yusuf, Muhammed Aasim MA
Publication Date: 2023

Variant appearance in text: BRAF: V600K
PubMed Link: 37033676
Variant Present in the following documents:
  • Main text
  • 10.1177_11795476231163961.pdf
View BVdb publication page



Peritoneal Carcinomatosis From Malignant Melanoma After Wide Local Excision of a T1a Lesion: A Case Report.

Cureus
Hager, Matthew M; Miller, John J; Wegener, Adam A; Yon, James J
Publication Date: 2023-03

Variant appearance in text: BRAF: V600k
PubMed Link: 37016648
Variant Present in the following documents:
  • Main text
  • cureus-0015-00000035730.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: BRAF: V600K
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Preoperative Mutational Analysis of Circulating Tumor Cells (CTCs) and Plasma-cfDNA Provides Complementary Information for Early Prediction of Relapse: A Pilot Study in Early-Stage Non-Small Cell Lung Cancer.

Cancers
Markou, A N AN; Londra, D D; Stergiopoulou, D D; Vamvakaris, I I; Potaris, K K; Pateras, I S IS; Kotsakis, A A; Georgoulias, V V; Lianidou, E E
Publication Date: 2023-03-21

Variant appearance in text: BRAF: 1798_1799delinsAA
PubMed Link: 36980762
Variant Present in the following documents:
  • Main text
  • cancers-15-01877.pdf
View BVdb publication page



Biomarkers for Outcome in Metastatic Melanoma in First Line Treatment with Immune Checkpoint Inhibitors.

Biomedicines
Mesti, Tanja T; Grašič Kuhar, Cvetka C; Ocvirk, Janja J
Publication Date: 2023-03-01

Variant appearance in text: N/A
PubMed Link: 36979727
Variant Present in the following documents:
View BVdb publication page



Eroded pigmented anogenital plaque in an elderly woman.

Jaad Case Reports
Nagalla, Raji R RR; Lee, Bonnie A BA; Smith, Janellen J; Kraus, Christina N CN
Publication Date: 2023-04

Variant appearance in text: BRAF: V600K
PubMed Link: 36969315
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Rethinking glutamine metabolism and the regulation of glutamine addiction by oncogenes in cancer.

Frontiers In Oncology
Ni, Rui R; Li, Ziwei Z; Li, Li L; Peng, Dan D; Ming, Yue Y; Li, Lin L; Liu, Yao Y
Publication Date: 2023

Variant appearance in text: BRAF: V600K
PubMed Link: 36959802
Variant Present in the following documents:
  • Main text
  • fonc-13-1143798.pdf
View BVdb publication page



The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma.

Nature Communications
Lim, Su Yin SY; Shklovskaya, Elena E; Lee, Jenny H JH; Pedersen, Bernadette B; Stewart, Ashleigh A; Ming, Zizhen Z; Irvine, Mal M; Shivalingam, Brindha B; Saw, Robyn P M RPM; Menzies, Alexander M AM; Carlino, Matteo S MS; Scolyer, Richard A RA; Long, Georgina V GV; Rizos, Helen H
Publication Date: 2023-03-18

Variant appearance in text: BRAF: V600K
PubMed Link: 36934113
Variant Present in the following documents:
  • 41467_2023_36979_MOESM1_ESM.pdf
View BVdb publication page



Feasibility of Point-of-Care Genomic Profiling in the Diagnosis and Treatment of Cancer of Unknown Primary.

The Oncologist
Wang, Xin X; Beharry, Andrea A; Sheffield, Brandon S BS; Cheema, Parneet K PK
Publication Date: 2023-03-18

Variant appearance in text: BRAF: V600K
PubMed Link: 36933203
Variant Present in the following documents:
  • oyad054_suppl_supplementary_table_s2.xlsx, sheet 1
View BVdb publication page



Long-Term Real-World Outcomes and Safety of Vemurafenib and Vemurafenib + Cobimetinib Therapy in Patients with BRAF-Mutated Melanoma.

Targeted Oncology
Piejko, Karolina K; Cybulska-Stopa, Bożena B; Ziętek, Marcin M; Dziura, Robert R; Galus, Łukasz Ł; Kempa-Kamińska, Natasza N; Ziółkowska, Barbara B; Rutkowska, Ewa E; Kopciński, Tomasz T; Kubiatowski, Tomasz T; Bal, Wiesław W; Suwiński, Rafał R; Mackiewicz, Jacek J; Kamińska-Winciorek, Grażyna G; Czarnecka, Anna M AM; Rutkowski, Piotr P
Publication Date: 2023-03-11

Variant appearance in text: BRAF: V600K
PubMed Link: 36906728
Variant Present in the following documents:
  • 11523_2023_Article_954.pdf
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: V600K
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Impact of Novel Treatments in Patients with Melanoma Brain Metastasis: Real-World Data.

Cancers
Derks, Sophie H A E SHAE; Jongen, Joost L M JLM; van der Meer, Edgar L EL; Ho, Li Shen LS; Slagter, Cleo C; Joosse, Arjen A; de Jonge, Maja J A MJA; Schouten, Joost W JW; Oomen-de Hoop, Esther E; van den Bent, Martin J MJ; van der Veldt, Astrid A M AAM
Publication Date: 2023-02-25

Variant appearance in text: BRAF: Val600Lys
PubMed Link: 36900253
Variant Present in the following documents:
  • cancers-15-01461.pdf
View BVdb publication page



Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine.

Acta Pharmaceutica Sinica. B
Lee, Yeuan Ting YT; Tan, Yi Jer YJ; Oon, Chern Ein CE
Publication Date: 2023-02

Variant appearance in text: BRAF: V600K
PubMed Link: 36873180
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Safety and rapid response of dabrafenib and trametinib therapy during hyperbilirubinemia in metastatic melanoma.

Frontiers In Oncology
Shalata, Walid W; Steckbeck, Rachel R; Polishchuk, Ilya I; Cohen, Ahron Yehonatan AY; Rouvinov, Keren K; Tokar, Margarita M; Abu Jama, Ashraf A; Abu Saleh, Omar O; Sheva, Kim K; Yakobson, Alexander A
Publication Date: 2023

Variant appearance in text: BRAF: V600K
PubMed Link: 36865793
Variant Present in the following documents:
  • Main text
  • fonc-13-1102330.pdf
View BVdb publication page



Precision oncology for BRAF-mutant cancers with BRAF and MEK inhibitors: from melanoma to tissue-agnostic therapy.

Esmo Open
Gouda, M A MA; Subbiah, V V
Publication Date: 2023-02-24

Variant appearance in text: BRAF: V600K
PubMed Link: 36842301
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1798_1799delinsAA
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Efficacy of immunotherapy for melanoma brain metastases in patients with concurrent corticosteroid exposure.

Cns Oncology
Tringale, Kathryn R KR; Reiner, Anne S AS; Sehgal, Ryka R RR; Panageas, Katherine K; Betof Warner, Allison S AS; Postow, Michael A MA; Moss, Nelson S NS
Publication Date: 2023-02-20

Variant appearance in text: BRAF: V600K
PubMed Link: 36802833
Variant Present in the following documents:
  • cns-12-93.pdf
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: V600K
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



Thyroid Langerhans cell histiocytosis concurrent with papillary thyroid carcinoma: A case report and literature review.

Frontiers In Medicine
Mi, Bin B; Wu, Di D; Fan, Yue Y; Thong, Benjamin Ka Seng BKS; Chen, Yudong Y; Wang, Xue X; Wang, Chaofu C
Publication Date: 2022

Variant appearance in text: BRAF: V600K
PubMed Link: 36743683
Variant Present in the following documents:
  • Main text
  • fmed-09-1105152.pdf
View BVdb publication page



Damage mapping techniques and the light they have shed on canonical and atypical UV photoproducts.

Frontiers In Genetics
Bohm, Kaitlynne A KA; Wyrick, John J JJ
Publication Date: 2022

Variant appearance in text: BRAF: V600K
PubMed Link: 36704334
Variant Present in the following documents:
  • Main text
  • fgene-13-1102593.pdf
View BVdb publication page