Multi-organ landscape of therapy-resistant melanoma.
Nature Medicine
Liu, Sixue S; Dharanipragada, Prashanthi P; Lomeli, Shirley H SH; Wang, Yan Y; Zhang, Xiao X; Yang, Zhentao Z; Lim, Raymond J RJ; Dumitras, Camelia C; Scumpia, Philip O PO; Dubinett, Steve M SM; Moriceau, Gatien G; Johnson, Douglas B DB; Moschos, Stergios J SJ; Lo, Roger S RS
A Complex of Pyrosequencing-Based Methods for Detection of Somatic Mutations in Codons 600 and 601 of the BRAF gene.
Sovremennye Tekhnologii V Meditsine
Dribnokhodova, O P OP; Esman, A S AS; Korchagin, V I VI; Bukharina, A Yu AY; Dunaeva, E A EA; Leshkina, G V GV; Borisova, E V EV; Voiciehovskaya, Ya A YA; Daoud, A I AI; Khlyavich, V N VN; Mironov, K O KO
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: BRAF: 1798G>A; Val600Met
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
Cellular Oncology (Dordrecht)
Coupe, Nicholas N; Guo, Lina L; Bridges, Esther E; Campo, Leticia L; Espinosa, Olivia O; Colling, Richard R; Marshall, Andrea A; Nandakumar, Ashwin A; van Stiphout, Ruud R; Buffa, Francesca M FM; Corrie, Pippa G PG; Middleton, Mark R MR; Macaulay, Valentine M VM
Sensitivities and Dependencies of BRAF Mutant Colorectal Cancer Cell Lines with or without PIK3CA Mutations for Discovery of Vulnerabilities with Therapeutic Potential.
Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.
The Journal Of Pathology
Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ
A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers-Analytical validation and performance evaluation with clinical samples.
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.
Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Sudha, Parvathi P; Ahsan, Aarif A; Ashby, Cody C; Kausar, Tasneem T; Khera, Akhil A; Kazeroun, Mohammad H MH; Hsu, Chih-Chao CC; Wang, Lin L; Fitzsimons, Evelyn E; Salminen, Outi O; Blaney, Patrick P; Czader, Magdalena M; Williams, Jonathan J; Abu Zaid, Mohammad I MI; Ansari-Pour, Naser N; Yong, Kwee L KL; van Rhee, Frits F; Pierceall, William E WE; Morgan, Gareth J GJ; Flynt, Erin E; Gooding, Sarah S; Abonour, Rafat R; Ramasamy, Karthik K; Thakurta, Anjan A; Walker, Brian A BA
Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation.
Journal For Immunotherapy Of Cancer
Wang, Minyu M; Zadeh, Soroor S; Pizzolla, Angela A; Thia, Kevin K; Gyorki, David E DE; McArthur, Grant A GA; Scolyer, Richard A RA; Long, Georgina G; Wilmott, James S JS; Andrews, Miles C MC; Au-Yeung, George G; Weppler, Ali A; Sandhu, Shahneen S; Trapani, Joseph A JA; Davis, Melissa J MJ; Neeson, Paul Joseph PJ
Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.
International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05
Variant appearance in text: BRAF: 1798G>A; Val600Met
Circulating Tumor DNA-Based Genotyping and Monitoring for Predicting Disease Relapses of Patients with Peripheral T-Cell Lymphomas.
Cancer Research And Treatment
Kim, Seok Jin SJ; Kim, Yeon Jeong YJ; Yoon, Sang Eun SE; Ryu, Kyung Ju KJ; Park, Bon B; Park, Donghyun D; Cho, Duck D; Kim, Hyun-Young HY; Cho, Junhun J; Ko, Young Hyeh YH; Park, Woong-Yang WY; Kim, Won Seog WS
The Use of ctDNA for BRAF Mutation Testing in Routine Clinical Practice in Patients with Advanced Melanoma.
Cancers
Sobczuk, Paweł P; Kozak, Katarzyna K; Kopeć, Sylwia S; Rogala, Paweł P; Świtaj, Tomasz T; Koseła-Paterczyk, Hanna H; Gos, Aleksandra A; Tysarowski, Andrzej A; Rutkowski, Piotr P
The Use of ctDNA for BRAF Mutation Testing in Routine Clinical Practice in Patients with Advanced Melanoma.
Cancers
Sobczuk, Paweł P; Kozak, Katarzyna K; Kopeć, Sylwia S; Rogala, Paweł P; Świtaj, Tomasz T; Koseła-Paterczyk, Hanna H; Gos, Aleksandra A; Tysarowski, Andrzej A; Rutkowski, Piotr P
Combined targeting of EGFR and BRAF triggers regression of osimertinib resistance by using osimertinib and vemurafenib concurrently in a patient with heterogeneity between different lesions.
Thoracic Cancer
Sun, Mengyao M; Wang, Xu X; Xu, Yinghui Y; Sun, Chao C; Guo, Ye Y; Qiu, Shi S; Zhao, Renshan R; Zhu, Wenhao W; Ma, Kewei K
Combined targeting of EGFR and BRAF triggers regression of osimertinib resistance by using osimertinib and vemurafenib concurrently in a patient with heterogeneity between different lesions.
Thoracic Cancer
Sun, Mengyao M; Wang, Xu X; Xu, Yinghui Y; Sun, Chao C; Guo, Ye Y; Qiu, Shi S; Zhao, Renshan R; Zhu, Wenhao W; Ma, Kewei K
Durable Response to Vemurafenib and Cobimetinib for the Treatment of BRAF-Mutated Metastatic Melanoma in Routine Clinical Practice.
Oncotargets And Therapy
Álamo, Mª Del Carmen MDC; Ochenduszko, Sebastian S; Crespo, Guillermo G; Corral, Mónica M; Oramas, Juana J; Sancho, Pilar P; Medina, Javier J; Garicano, Fernando F; López, Pedro P; Campos Balea, Begoña B; Rodríguez Garzotto, Analia A; Muñoz-Couselo, Eva E
BRAF Signaling Inhibition in Glioblastoma: Which Clinical Perspectives?
Frontiers In Oncology
Bouchè, Victoria V; Aldegheri, Giovanni G; Donofrio, Carmine Antonio CA; Fioravanti, Antonio A; Roberts-Thomson, Samuel S; Fox, Stephen B SB; Schettini, Francesco F; Generali, Daniele D
The retrospective molecular analysis of large or giant congenital melanocytic nevi in a group of Polish children.
Journal Of Mother And Child
Wertheim-Tysarowska, Katarzyna K; Szczygielski, Orest O; Seliga, Katarzyna K; Tysarowski, Andrzej A; Bal, Jerzy J; Michalak, Elżbieta E; Rygiel, Agnieszka Magdalena AM; Sawicka, Ewa E
Publication Date: 2021-10-11
Variant appearance in text: BRAF: 1798G>A; Val600Met
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Defining the Criteria for Reflex Testing for BRAF Mutations in Cutaneous Melanoma Patients.
Cancers
Zhou, Sarah S; Sikorski, Daniel D; Xu, Honghao H; Zubarev, Andrei A; Chergui, May M; Lagacé, François F; Miller, Wilson H WH; Redpath, Margaret M; Ghazal, Stephanie S; Butler, Marcus O MO; Petrella, Teresa M TM; Claveau, Joël J; Nessim, Carolyn C; Salopek, Thomas G TG; Gniadecki, Robert R; Litvinov, Ivan V IV