BRAF c.1790T>G ;(p.L597R)

Variant ID: 7-140453145-A-C

NM_004333.4(BRAF):c.1790T>G;(p.L597R)

This variant was identified in 187 publications

View GRCh38 version.




Publications:


PD-L1-negative non-small cell lung cancer harbouring a rare BRAF mutation with successful treatment of first-line pembrolizumab plus chemotherapy: A case report and review the literature.

Respirology Case Reports
Do, Kien Hung KH; Nguyen, Tai Van TV; Nguyen Thi Bich, Phuong P; Nguyen, Gia Hoang GH; Nguyen, Chu Van CV
Publication Date: 2023-06

Variant appearance in text: BRAF: L597R
PubMed Link: 37151366
Variant Present in the following documents:
  • Main text
  • RCR2-11-e01155.pdf
View BVdb publication page



An integrated model for predicting KRAS dependency.

Plos Computational Biology
Tsai, Yihsuan S YS; Chareddy, Yogitha S YS; Price, Brandon A BA; Parker, Joel S JS; Pecot, Chad V CV
Publication Date: 2023-05-04

Variant appearance in text: BRAF: L597R
PubMed Link: 37141389
Variant Present in the following documents:
  • Main text
  • pcbi.1011095.pdf
View BVdb publication page



An Editorial on the Special Issue 'Hsp90 Structure, Mechanism and Disease'.

Biomolecules
Prodromou, Chrisostomos C
Publication Date: 2023-03-17

Variant appearance in text: BRAF: L597R
PubMed Link: 36979482
Variant Present in the following documents:
  • Main text
  • biomolecules-13-00547.pdf
View BVdb publication page



Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09

Variant appearance in text: N/A
PubMed Link: 36922933
Variant Present in the following documents:
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: L597R
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1790T>G; Leu597Arg
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Efficacy of Dabrafenib and Trametinib in a Patient with Squamous-Cell Carcinoma, with Mutation p.D594G in BRAF and p.R461* in NF1 Genes-A Case Report with Literature Review.

International Journal Of Molecular Sciences
Grenda, Anna A; Krawczyk, Pawel P; Targowska-Duda, Katarzyna M KM; Kieszko, Robert R; Paśnik, Iwona I; Milanowski, Janusz J
Publication Date: 2023-01-07

Variant appearance in text: BRAF: L597R
PubMed Link: 36674722
Variant Present in the following documents:
  • Main text
  • ijms-24-01195.pdf
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
View BVdb publication page



Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj
Wagner, Sebastian A SA
Publication Date: 2022

Variant appearance in text: BRAF: L597R
PubMed Link: 36275468
Variant Present in the following documents:
  • peerj-10-14126.pdf
View BVdb publication page



Whole-exome sequencing analysis identifies distinct mutational profile and novel prognostic biomarkers in primary gastrointestinal diffuse large B-cell lymphoma.

Experimental Hematology & Oncology
Li, Shan-Shan SS; Zhai, Xiao-Hui XH; Liu, Hai-Ling HL; Liu, Ting-Zhi TZ; Cao, Tai-Yuan TY; Chen, Dong-Mei DM; Xiao, Le-Xin LX; Gan, Xiao-Qin XQ; Cheng, Ke K; Hong, Wan-Jia WJ; Huang, Yan Y; Lian, Yi-Fan YF; Xiao, Jian J
Publication Date: 2022-10-15

Variant appearance in text: BRAF: 1790T>G; Leu597Arg; rs121913366
PubMed Link: 36243813
Variant Present in the following documents:
  • 40164_2022_325_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive characterization of genomic and radiologic features reveals distinct driver patterns of RTK/RAS pathway in ground-glass opacity pulmonary nodules.

International Journal Of Cancer
Yu, Fenglei F; Peng, Muyun M; Bai, Jing J; Zhu, Xiuli X; Zhang, Bingyu B; Tang, Jingqun J; Liu, Wenliang W; Chen, Chen C; Wang, Xiang X; Chen, Mingjiu M; Tan, Sichuang S; Sun, Yi Y; Liang, Qingchun Q; Li, Jina J; Hu, Yan Y; Liao, Aihui A; Hu, Huali H; He, Yu Y; Xiao, Xiao X; Wang, Bin B; Xing, Guanlan G; Xu, Yaping Y; Chen, Rongrong R; Xia, Xuefeng X; Chen, Xiaofeng X
Publication Date: 2022-12-01

Variant appearance in text: BRAF: L597R
PubMed Link: 36029220
Variant Present in the following documents:
  • IJC-151-2020-s001.pdf
  • IJC-151-2020.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Recognition of BRAF by CDC37 and Re-Evaluation of the Activation Mechanism for the Class 2 BRAF-L597R Mutant.

Biomolecules
Bjorklund, Dennis M DM; Morgan, R Marc L RML; Oberoi, Jasmeen J; Day, Katie L I M KLIM; Galliou, Panagiota A PA; Prodromou, Chrisostomos C
Publication Date: 2022-06-28

Variant appearance in text: BRAF: L597R
PubMed Link: 35883461
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00905.pdf
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: BRAF: L597R
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age.

Nature Communications
Burkhardt, Birgit B; Michgehl, Ulf U; Rohde, Jonas J; Erdmann, Tabea T; Berning, Philipp P; Reutter, Katrin K; Rohde, Marius M; Borkhardt, Arndt A; Burmeister, Thomas T; Dave, Sandeep S; Tzankov, Alexandar A; Dugas, Martin M; Sandmann, Sarah S; Fend, Falko F; Finger, Jasmin J; Mueller, Stephanie S; Gökbuget, Nicola N; Haferlach, Torsten T; Kern, Wolfgang W; Hartmann, Wolfgang W; Klapper, Wolfram W; Oschlies, Ilske I; Richter, Julia J; Kontny, Udo U; Lutz, Mathias M; Maecker-Kolhoff, Britta B; Ott, German G; Rosenwald, Andreas A; Siebert, Reiner R; von Stackelberg, Arend A; Strahm, Brigitte B; Woessmann, Wilhelm W; Zimmermann, Martin M; Zapukhlyak, Myroslav M; Grau, Michael M; Lenz, Georg G
Publication Date: 2022-07-06

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 35794096
Variant Present in the following documents:
  • 41467_2022_31355_MOESM5_ESM.xlsx, sheet 2
View BVdb publication page



Non-Equilibrium Protein Folding and Activation by ATP-Driven Chaperones.

Biomolecules
Xu, Huafeng H
Publication Date: 2022-06-15

Variant appearance in text: BRAF: L597R
PubMed Link: 35740957
Variant Present in the following documents:
  • biomolecules-12-00832.pdf
View BVdb publication page



A bipartite graph-based expected networks approach identifies DDR genes not associated with TMB yet predictive of immune checkpoint blockade response.

Cell Reports. Medicine
Weir, William H WH; Mucha, Peter J PJ; Kim, William Y WY
Publication Date: 2022-05-17

Variant appearance in text: BRAF: 1790T>G; Leu597Arg
PubMed Link: 35584624
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
View BVdb publication page



Multicenter Observational Study on Metastatic Non-Small Cell Lung Cancer Harboring BRAF Mutations: Focus on Clinical Characteristics and Treatment Outcome of V600E and Non-V600E Subgroups.

Cancers
Perrone, Fabiana F; Mazzaschi, Giulia G; Minari, Roberta R; Verzè, Michela M; Azzoni, Cinzia C; Bottarelli, Lorena L; Nizzoli, Rita R; Pluchino, Monica M; Altimari, Annalisa A; Gruppioni, Elisa E; Sperandi, Francesca F; Andrini, Elisa E; Guaitoli, Giorgia G; Bertolini, Federica F; Barbieri, Fausto F; Bettelli, Stefania S; Longo, Lucia L; Pagano, Maria M; Bonelli, Candida C; Tagliavini, Elena E; Nicoli, Davide D; Ubiali, Alessandro A; Zangrandi, Adriano A; Trubini, Serena S; Proietto, Manuela M; Gnetti, Letizia L; Tiseo, Marcello M
Publication Date: 2022-04-16

Variant appearance in text: BRAF: L597R
PubMed Link: 35454926
Variant Present in the following documents:
  • Main text
  • cancers-14-02019.pdf
View BVdb publication page



Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing.

Molecular Cancer Research : Mcr
Pham, Minh-Tam MT; Gupta, Anuj A; Gupta, Harshath H; Vaghasia, Ajay A; Skaist, Alyza A; Garrison, McKinzie A MA; Coulter, Jonathan B JB; Haffner, Michael C MC; Zheng, S Lilly SL; Xu, Jianfeng J; DeStefano Shields, Christina C; Isaacs, William B WB; Wheelan, Sarah J SJ; Nelson, William G WG; Yegnasubramanian, Srinivasan S
Publication Date: 2022-07-06

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 35452513
Variant Present in the following documents:
  • mcr-21-0683_supplementary_tables_1-13_suppst1-13.xlsx, sheet 7
View BVdb publication page



Targeted Therapy for Melanomas Without BRAF V600 Mutations.

Current Treatment Options In Oncology
Menzer, Christian C; Hassel, Jessica C JC
Publication Date: 2022-06

Variant appearance in text: BRAF: L597R
PubMed Link: 35380338
Variant Present in the following documents:
  • Main text
  • 11864_2022_Article_946.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: BRAF: 1790T>G; Leu597Arg
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data2.xlsx, sheet 1
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: BRAF: L597R
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 12
View BVdb publication page



[Strategic Exploration of Targeted Therapy for BRAF Non-V600E Mutant Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Zhang, Hongxia H; Gao, Jinsheng J; Guo, Wei W; Yu, Bo B; Yang, Haitao H; Liu, Yutao Y
Publication Date: 2022-02-20

Variant appearance in text: BRAF: L597R
PubMed Link: 35224961
Variant Present in the following documents:
  • Main text
  • zgfazz-25-2-86.pdf
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: BRAF: Leu597Arg
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer.

Therapeutic Advances In Medical Oncology
Shi, Min M; Yuan, Hong H; Ji, Jun J; Zhang, Shouwei S; Li, Qingyuan Q; Chen, Yawei Y; Gong, Xiaoli X; Zhu, Zhenggang Z; Zhang, Jun J
Publication Date: 2022

Variant appearance in text: rs121913366
PubMed Link: 35096147
Variant Present in the following documents:
  • sj-xls-4-tam-10.1177_17588359211070643.xls, sheet 1
View BVdb publication page



Genetic Profile of Adenomatoid Odontogenic Tumor and Ameloblastoma. A Systematic Review.

Frontiers In Oral Health
Marín, Constanza C; Niklander, Sven E SE; Martínez-Flores, René R
Publication Date: 2021

Variant appearance in text: BRAF: L597R
PubMed Link: 35048068
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Molecular Pathology of Odontogenic Tumors: Expanding the Spectrum of MAPK Pathway Driven Tumors.

Frontiers In Oral Health
Guimarães, Letícia Martins LM; Coura, Bruna Pizziolo BP; Gomez, Ricardo Santiago RS; Gomes, Carolina Cavalieri CC
Publication Date: 2021

Variant appearance in text: BRAF: L597R
PubMed Link: 35048058
Variant Present in the following documents:
  • Main text
  • froh-02-740788.pdf
View BVdb publication page



Molecular Profiling and Novel Therapeutic Strategies for Mucosal Melanoma: A Comprehensive Review.

International Journal Of Molecular Sciences
Indini, Alice A; Roila, Fausto F; Grossi, Francesco F; Massi, Daniela D; Mandalà, Mario M
Publication Date: 2021-12-23

Variant appearance in text: BRAF: L597R
PubMed Link: 35008570
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular Profiling and Novel Therapeutic Strategies for Mucosal Melanoma: A Comprehensive Review.

International Journal Of Molecular Sciences
Indini, Alice A; Roila, Fausto F; Grossi, Francesco F; Massi, Daniela D; Mandalà, Mario M
Publication Date: 2021-12-23

Variant appearance in text: BRAF: L597R
PubMed Link: 35008570
Variant Present in the following documents:
  • Main text
View BVdb publication page



Untangling the KRAS mutated lung cancer subsets and its therapeutic implications.

Molecular Biomedicine
Ritu, Kulshrestha K; Kumar, Pawan P; Singh, Amit A; Nupur, K K; Spalgias, Sonam S; Mrigpuri, Parul P; Rajkumar,
Publication Date: 2021-12-17

Variant appearance in text: BRAF: L597R
PubMed Link: 34918209
Variant Present in the following documents:
  • Main text
  • 43556_2021_Article_61.pdf
View BVdb publication page



Untangling the KRAS mutated lung cancer subsets and its therapeutic implications.

Molecular Biomedicine (Online)
Ritu, Kulshrestha K; Kumar, Pawan P; Singh, Amit A; Nupur, K K; Spalgias, Sonam S; Mrigpuri, Parul P; Rajkumar,
Publication Date: 2021-12-17

Variant appearance in text: BRAF: L597R
PubMed Link: 34918209
Variant Present in the following documents:
  • Main text
  • 43556_2021_Article_61.pdf
View BVdb publication page



Evaluation of the Mutation Profile via Next-Generation Sequencing in a Turkish Population With Non-small Cell Lung Cancer.

Balkan Medical Journal
Kahraman Çetin, Nesibe N; Erdoğdu, İbrahim Halil İH; Bozkurt, Emin E; Meteoğlu, İbrahim İ
Publication Date: 2021-11

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 34860166
Variant Present in the following documents:
  • bmj-38-6-382.pdf
View BVdb publication page



Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology
Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS
Publication Date: 2022-01

Variant appearance in text: BRAF: 1790T>G; Leu597Arg; rs121913366
PubMed Link: 34800919
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer.

Translational Oncology
Metzenmacher, Martin M; Hegedüs, Balazs B; Forster, Jan J; Schramm, Alexander A; Horn, Peter A PA; Klein, Christoph A CA; Bielefeld, Nicola N; Ploenes, Till T; Aigner, Clemens C; Theegarten, Dirk D; Schildhaus, Hans-Ulrich HU; Siveke, Jens T JT; Schuler, Martin M; Lueong, Smiths S SS
Publication Date: 2021-11-17

Variant appearance in text: BRAF: 1790T>G; Leu597Arg; rs121913366
PubMed Link: 34800919
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Molecular testing for colorectal cancer: Clinical applications.

World Journal Of Gastrointestinal Oncology
Imyanitov, Evgeny E; Kuligina, Ekaterina E
Publication Date: 2021-10-15

Variant appearance in text: BRAF: L597R
PubMed Link: 34721767
Variant Present in the following documents:
  • WJGO-13-1288.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: L597R
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Genomic Profiling Reveals the Molecular Landscape of Gastrointestinal Tract Cancers in Chinese Patients.

Frontiers In Genetics
Zhu, Chunrong C; Zhu, Liangjun L; Gu, Yanhong Y; Liu, Ping P; Tong, Xiaoling X; Wu, Guozhong G; Zhu, Wenyu W; Shen, Wenxiang W; Bao, Hua H; Ma, Xiangyuan X; Yu, Ruoying R; Wu, Xue X; Zhu, Dongqin D; Shu, Yongqian Y; Feng, Jifeng J
Publication Date: 2021

Variant appearance in text: BRAF: L597R
PubMed Link: 34594355
Variant Present in the following documents:
  • Main text
  • Table_2.xlsx, sheet 1
View BVdb publication page



Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring.

International Journal Of Molecular Sciences
Kamińska, Paula P; Buszka, Karolina K; Zabel, Maciej M; Nowicki, Michał M; Alix-Panabières, Catherine C; Budna-Tukan, Joanna J
Publication Date: 2021-09-08

Variant appearance in text: BRAF: L597R
PubMed Link: 34575876
Variant Present in the following documents:
  • Main text
  • ijms-22-09714.pdf
View BVdb publication page



Co-mutations of epidermal growth factor receptor and BRAF in Chinese non-small cell lung cancer patients.

Annals Of Translational Medicine
Peng, Panli P; Lv, Guoli G; Hu, Jinwei J; Wang, Kai K; Lv, Junhong J; Guo, Gang G
Publication Date: 2021-08

Variant appearance in text: BRAF: L597R
PubMed Link: 34532458
Variant Present in the following documents:
  • Main text
  • atm-09-16-1321.pdf
View BVdb publication page



Molecular profiling and identification of prognostic factors in Chinese patients with small bowel adenocarcinoma.

Cancer Science
Pan, Hongming H; Cheng, Huanqing H; Wang, Huina H; Ge, Weiting W; Yuan, Meiqin M; Jiang, Sujing S; Wan, Xiangbo X; Dong, Ying Y; Liu, Zhen Z; Zhao, Rongjie R; Fang, Yong Y; Lou, Feng F; Cao, Shanbo S; Han, Weidong W
Publication Date: 2021-11

Variant appearance in text: BRAF: L597R
PubMed Link: 34449929
Variant Present in the following documents:
  • Main text
  • CAS-112-4758.pdf
View BVdb publication page



A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer.

Scientific Reports
Palit, Sander A L SAL; van Dorp, Jeroen J; Vis, Daniel D; Lieftink, Cor C; Linder, Simon S; Beijersbergen, Roderick R; Bergman, Andries M AM; Zwart, Wilbert W; van der Heijden, Michiel S MS
Publication Date: 2021-07-01

Variant appearance in text: BRAF: L597R
PubMed Link: 34211036
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_93107.pdf
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Treatment of Rare Mutations in Patients with Lung Cancer.

Biomedicines
Taha, Tarek T; Khoury, Rasha R; Brenner, Ronen R; Nasrallah, Haitam H; Shofaniyeh, Irena I; Yousef, Samih S; Agbarya, Abed A
Publication Date: 2021-05-11

Variant appearance in text: BRAF: L597R
PubMed Link: 34064757
Variant Present in the following documents:
  • Main text
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High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens.

Scientific Reports
Cheng, Lauren Y LY; Haydu, Lauren E LE; Song, Ping P; Nie, Jianyi J; Tetzlaff, Michael T MT; Kwong, Lawrence N LN; Gershenwald, Jeffrey E JE; Davies, Michael A MA; Zhang, David Yu DY
Publication Date: 2021-04-27

Variant appearance in text: BRAF: L597R
PubMed Link: 33907234
Variant Present in the following documents:
  • Main text
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Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.

Chest
Roosan, Moom R MR; Mambetsariev, Isa I; Pharaon, Rebecca R; Fricke, Jeremy J; Husain, Hatim H; Reckamp, Karen L KL; Koczywas, Marianna M; Massarelli, Erminia E; Bild, Andrea H AH; Salgia, Ravi R
Publication Date: 2021-09

Variant appearance in text: BRAF: L597R
PubMed Link: 33878340
Variant Present in the following documents:
  • Main text
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Association of TRF2 expression and myeloid-derived suppressor cells infiltration with clinical outcome of patients with cutaneous melanoma.

Oncoimmunology
Ilié, Marius M; Lantéri, Elisabeth E; Chamorey, Emmanuel E; Thamphya, Brice B; Hamila, Marame M; Montaudié, Henri H; Picard-Gauci, Alexandra A; Gardrat, Sophie S; Passeron, Thierry T; Lassalle, Sandra S; Long-Mira, Elodie E; Cherfils-Vicini, Julien J; Gilson, Eric E; Hofman, Véronique V; Hofman, Paul P
Publication Date: 2021-03-19

Variant appearance in text: BRAF: L597R
PubMed Link: 33796413
Variant Present in the following documents:
  • Main text
  • KONI_10_1901446.pdf
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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: BRAF: 1790T>G; L597R
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
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BRAF AMP Frequently Co-occurs With IDH1/2, TP53, and ATRX Mutations in Adult Patients With Gliomas and Is Associated With Poorer Survival Than That of Patients Harboring BRAF V600E.

Frontiers In Oncology
Da, Rong R; Wang, Maode M; Jiang, Haitao H; Wang, Tuo T; Wang, Wei W
Publication Date: 2020

Variant appearance in text: BRAF: L597R
PubMed Link: 33489866
Variant Present in the following documents:
  • Main text
  • Table_1.xlsx, sheet 1
  • fonc-10-531968.pdf
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