BRAF c.1786G>C ;(p.G596R)

Variant ID: 7-140453149-C-G

NM_004333.4(BRAF):c.1786G>C;(p.G596R)

This variant was identified in 143 publications

View GRCh38 version.




Publications:


The Genomic Landscape of Melanoma and Its Therapeutic Implications.

Genes
Yang, Ting-Ting TT; Yu, Sebastian S; Ke, Chiao-Li Khale CK; Cheng, Shih-Tsung ST
Publication Date: 2023-04-29

Variant appearance in text: BRAF: G596R
PubMed Link: 37239381
Variant Present in the following documents:
  • Main text
  • genes-14-01021.pdf
View BVdb publication page



An integrated model for predicting KRAS dependency.

Plos Computational Biology
Tsai, Yihsuan S YS; Chareddy, Yogitha S YS; Price, Brandon A BA; Parker, Joel S JS; Pecot, Chad V CV
Publication Date: 2023-05-04

Variant appearance in text: BRAF: G596R
PubMed Link: 37141389
Variant Present in the following documents:
  • Main text
  • pcbi.1011095.pdf
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: G596R
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Association of BRAF Variants With Disease Characteristics, Prognosis, and Targeted Therapy Response in Intrahepatic Cholangiocarcinoma.

Jama Network Open
Xin, Hao-Yang HY; Sun, Rong-Qi RQ; Zou, Ji-Xue JX; Wang, Peng-Cheng PC; Wang, Jia-Yin JY; Ye, Yu-Hang YH; Liu, Kai-Xuan KX; Hu, Zhi-Qiang ZQ; Zhou, Zheng-Jun ZJ; Fan, Jia J; Zhou, Jian J; Zhou, Shao-Lai SL
Publication Date: 2023-03-01

Variant appearance in text: BRAF: G596R
PubMed Link: 36867406
Variant Present in the following documents:
  • Main text
  • jamanetwopen-e231476-s001.pdf
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: BRAF: G596R
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: G596R
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Combined KRAS G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS G12C -driven cancers by addressing intrinsic and acquired resistance.

Biorxiv : The Preprint Server For Biology
Thatikonda, Venu V; Lu, Hengyu H; Jurado, Sabine S; Kostyrko, Kaja K; Bristow, Christopher A CA; Bosch, Karin K; Feng, Ningping N; Gao, Sisi S; Gerlach, Daniel D; Gmachl, Michael M; Lieb, Simone S; Jeschko, Astrid A; Machado, Annette A AA; Marszalek, Ethan D ED; Mahendra, Mikhila M; Jaeger, Philipp A PA; Sorokin, Alexey A; Strauss, Sandra S; Trapani, Francesca F; Kopetz, Scott S; Vellano, Christopher P CP; Petronczki, Mark M; Kraut, Norbert N; Heffernan, Timothy P TP; Marszalek, Joseph R JR; Pearson, Mark M; Waizenegger, Irene I; Hofmann, Marco H MH
Publication Date: 2023-01-23

Variant appearance in text: BRAF: G596R
PubMed Link: 36747713
Variant Present in the following documents:
  • media-1.xlsx, sheet 4
View BVdb publication page



Targeting KRAS G12C mutations in colorectal cancer.

Gastroenterology Report
Zhao, Ming-He MH; Wu, Ai-Wen AW
Publication Date: 2023

Variant appearance in text: BRAF: G596R
PubMed Link: 36632627
Variant Present in the following documents:
  • Main text
  • goac083.pdf
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: BRAF: G596R
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Sensitivities and Dependencies of BRAF Mutant Colorectal Cancer Cell Lines with or without PIK3CA Mutations for Discovery of Vulnerabilities with Therapeutic Potential.

Medicina (Kaunas, Lithuania)
Voutsadakis, Ioannis A IA
Publication Date: 2022-10-21

Variant appearance in text: BRAF: G596R
PubMed Link: 36295658
Variant Present in the following documents:
  • Main text
  • medicina-58-01498.pdf
View BVdb publication page



Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj
Wagner, Sebastian A SA
Publication Date: 2022

Variant appearance in text: BRAF: G596R
PubMed Link: 36275468
Variant Present in the following documents:
  • peerj-10-14126.pdf
View BVdb publication page



Conquering oncogenic KRAS and its bypass mechanisms.

Theranostics
Hou, Pingping P; Wang, Y Alan YA
Publication Date: 2022

Variant appearance in text: BRAF: G596R
PubMed Link: 35966590
Variant Present in the following documents:
  • Main text
  • thnov12p5691.pdf
View BVdb publication page



Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.

Scientific Reports
Denisova, Oxana V OV; Merisaari, Joni J; Kaur, Amanpreet A; Yetukuri, Laxman L; Jumppanen, Mikael M; von Schantz-Fant, Carina C; Ohlmeyer, Michael M; Wennerberg, Krister K; Aittokallio, Tero T; Taipale, Mikko M; Westermarck, Jukka J
Publication Date: 2022-08-13

Variant appearance in text: BRAF: G596R
PubMed Link: 35963891
Variant Present in the following documents:
  • 41598_2022_18118_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1786G>C; G596R; rs121913361
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: BRAF: G596R
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Characteristics of and Treatment Strategies for Advanced EGFR-Mutant NSCLC With Concomitant BRAF Variations.

Jto Clinical And Research Reports
Wei, Xue-Wu XW; Deng, Jia-Yi JY; Xu, Chong-Rui CR; Chen, Zhi-Hong ZH; Zhu, Dong-Qin DQ; Wu, Qian Q; Zhang, Xu-Chao XC; Wu, Yi-Long YL; Zhou, Qing Q
Publication Date: 2022-07

Variant appearance in text: BRAF: G596R
PubMed Link: 35789792
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: BRAF: G596R
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology
Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q
Publication Date: 2021

Variant appearance in text: BRAF: G596R
PubMed Link: 35273907
Variant Present in the following documents:
  • Main text
  • Table_7.xlsx, sheet 1
  • fonc-11-751106.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data2.xlsx, sheet 1
View BVdb publication page



Epidemiology and Molecular Profile of Mucosal Melanoma: A Population-Based Study in Southern Europe.

Cancers
Carbó-Bagué, Anna A; Rubió-Casadevall, Jordi J; Puigdemont, Montserrat M; Sanvisens, Arantza A; Oliveras, Glòria G; Coll, Mònica M; Del Olmo, Bernat B; Perez-Bueno, Ferran F; Marcos-Gragera, Rafael R
Publication Date: 2022-02-03

Variant appearance in text: BRAF: G596R
PubMed Link: 35159047
Variant Present in the following documents:
  • Main text
  • cancers-14-00780.pdf
View BVdb publication page



Epidemiology and Molecular Profile of Mucosal Melanoma: A Population-Based Study in Southern Europe.

Cancers
Carbó-Bagué, Anna A; Rubió-Casadevall, Jordi J; Puigdemont, Montserrat M; Sanvisens, Arantza A; Oliveras, Glòria G; Coll, Mònica M; Del Olmo, Bernat B; Perez-Bueno, Ferran F; Marcos-Gragera, Rafael R
Publication Date: 2022-02-03

Variant appearance in text: BRAF: G596R
PubMed Link: 35159047
Variant Present in the following documents:
  • Main text
  • cancers-14-00780.pdf
View BVdb publication page



Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics
Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y
Publication Date: 2022-01-15

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 35031014
Variant Present in the following documents:
  • 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics
Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y
Publication Date: 2022-01-15

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 35031014
Variant Present in the following documents:
  • 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas.

Oncotarget
Hsu, Robert R; Baca, Yasmine Y; Xiu, Joanne J; Wang, Rongfu R; Bodor, J Nicholas JN; Kim, Chul C; Khan, Hina H; Mamdani, Hirva H; Nagasaka, Misako M; Puri, Sonam S; Liu, Stephen V SV; Korn, W Michael WM; Nieva, Jorge J JJ
Publication Date: 2021-12-07

Variant appearance in text: BRAF: G596R
PubMed Link: 34917263
Variant Present in the following documents:
  • oncotarget-12-2449-s001.pdf
View BVdb publication page



Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology
Li, Na N; Wang, Jiahong J; Zhan, Xianquan X
Publication Date: 2021

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 34887858
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.

Journal For Immunotherapy Of Cancer
Hu, Chunhong C; Zhao, Lishu L; Liu, Wenliang W; Fan, Songqing S; Liu, Junqi J; Liu, Yuxuan Y; Liu, Xiaohan X; Shu, Long L; Liu, Xianling X; Liu, Ping P; Deng, Chao C; Qiu, Zhenhua Z; Chen, Chen C; Jiang, Yi Y; Liang, Qingchun Q; Yang, Lingling L; Shao, Yang Y; He, Qiongzhi Q; Yu, Danlei D; Zeng, Yue Y; Li, Yizheng Y; Pan, Yue Y; Zhang, Sujuan S; Shi, Shenghao S; Peng, Yurong Y; Wu, Fang F
Publication Date: 2021-12

Variant appearance in text: BRAF: G596R
PubMed Link: 34887263
Variant Present in the following documents:
  • jitc-2021-003773.pdf
View BVdb publication page



Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications
Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J
Publication Date: 2021-11-19

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 34799585
Variant Present in the following documents:
  • 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications
Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J
Publication Date: 2021-11-19

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 34799585
Variant Present in the following documents:
  • 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: G596R
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



BRAF mutations may identify a clinically distinct subset of glioblastoma.

Scientific Reports
McNulty, Samantha N SN; Schwetye, Katherine E KE; Ferguson, Cole C; Storer, Chad E CE; Ansstas, George G; Kim, Albert H AH; Gutmann, David H DH; Rubin, Joshua B JB; Head, Richard D RD; Dahiya, Sonika S
Publication Date: 2021-10-08

Variant appearance in text: BRAF: G596R
PubMed Link: 34625582
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_99278.pdf
View BVdb publication page



Co-mutations of epidermal growth factor receptor and BRAF in Chinese non-small cell lung cancer patients.

Annals Of Translational Medicine
Peng, Panli P; Lv, Guoli G; Hu, Jinwei J; Wang, Kai K; Lv, Junhong J; Guo, Gang G
Publication Date: 2021-08

Variant appearance in text: BRAF: G596R
PubMed Link: 34532458
Variant Present in the following documents:
  • Main text
  • atm-09-16-1321.pdf
View BVdb publication page



Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies.

Jco Precision Oncology
Hendifar, Andrew A; Blais, Edik M EM; Wolpin, Brian B; Subbiah, Vivek V; Collisson, Eric E; Singh, Isha I; Cannon, Timothy T; Shaw, Kenna K; Petricoin, Emanuel F EF; Klempner, Samuel S; Lyons, Emily E; Wang-Gillam, Andrea A; Pishvaian, Michael J MJ; O'Reilly, Eileen M EM
Publication Date: 2021

Variant appearance in text: BRAF: G596R
PubMed Link: 34476331
Variant Present in the following documents:
  • po-5-po.20.00494.pdf
View BVdb publication page



Implementation of Next Generation Sequencing-Based Liquid Biopsy for Clinical Molecular Diagnostics in Non-Small Cell Lung Cancer (NSCLC) Patients.

Diagnostics (Basel, Switzerland)
Zulato, Elisabetta E; Tosello, Valeria V; Nardo, Giorgia G; Bonanno, Laura L; Del Bianco, Paola P; Indraccolo, Stefano S
Publication Date: 2021-08-13

Variant appearance in text: BRAF: Gly596Arg
PubMed Link: 34441402
Variant Present in the following documents:
  • Main text
  • diagnostics-11-01468.pdf
View BVdb publication page



Opportunities and Challenges of Small Molecule Induced Targeted Protein Degradation.

Frontiers In Cell And Developmental Biology
He, Ming M; Lv, Wenxing W; Rao, Yu Y
Publication Date: 2021

Variant appearance in text: BRAF: G596R
PubMed Link: 34249939
Variant Present in the following documents:
  • Main text
View BVdb publication page



Blockage of Cholinergic Signaling via Muscarinic Acetylcholine Receptor 3 Inhibits Tumor Growth in Human Colorectal Adenocarcinoma.

Cancers
Hering, Nina A NA; Liu, Verena V; Kim, Rayoung R; Weixler, Benjamin B; Droeser, Raoul A RA; Arndt, Marco M; Pozios, Ioannis I; Beyer, Katharina K; Kreis, Martin E ME; Seeliger, Hendrik H
Publication Date: 2021-06-28

Variant appearance in text: BRAF: G596R
PubMed Link: 34203220
Variant Present in the following documents:
  • Main text
View BVdb publication page



LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer.

Cancer Research
Miller, Samuel A SA; Policastro, Robert A RA; Sriramkumar, Shruthi S; Lai, Tim T; Huntington, Thomas D TD; Ladaika, Christopher A CA; Kim, Daeho D; Hao, Chunhai C; Zentner, Gabriel E GE; O'Hagan, Heather M HM
Publication Date: 2021-07-15

Variant appearance in text: BRAF: G596R
PubMed Link: 34035083
Variant Present in the following documents:
  • Main text
View BVdb publication page



Sensitivity and Usefulness of VE1 Immunohistochemical Staining in Acral Melanomas with BRAF Mutation.

Annals Of Dermatology
Suh, Min Song MS; Choi, Yoo Duk YD; Lee, Jee-Bum JB; Lee, Seung-Chul SC; Won, Young Ho YH; Yun, Sook Jung SJ
Publication Date: 2018-10

Variant appearance in text: BRAF: G596R
PubMed Link: 33911478
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences
Fois, Sara S SS; Paliogiannis, Panagiotis P; Zinellu, Angelo A; Fois, Alessandro G AG; Cossu, Antonio A; Palmieri, Giuseppe G
Publication Date: 2021-01-09

Variant appearance in text: BRAF: G596R
PubMed Link: 33435440
Variant Present in the following documents:
  • Main text
  • ijms-22-00612.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
Selenica, Pier P; Alemar, Barbara B; Matrai, Cathleen C; Talia, Karen L KL; Veras, Emanuela E; Hussein, Yaser Y; Oliva, Esther E; Beets-Tan, Regina G H RGH; Mikami, Yoshiki Y; McCluggage, W Glenn WG; Kiyokawa, Takako T; Weigelt, Britta B; Park, Kay J KJ; Murali, Rajmohan R
Publication Date: 2021-06

Variant appearance in text: BRAF: G596R
PubMed Link: 33318584
Variant Present in the following documents:
  • Main text
  • nihms-1642900.pdf
View BVdb publication page



Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
Selenica, Pier P; Alemar, Barbara B; Matrai, Cathleen C; Talia, Karen L KL; Veras, Emanuela E; Hussein, Yaser Y; Oliva, Esther E; Beets-Tan, Regina G H RGH; Mikami, Yoshiki Y; McCluggage, W Glenn WG; Kiyokawa, Takako T; Weigelt, Britta B; Park, Kay J KJ; Murali, Rajmohan R
Publication Date: 2021-06

Variant appearance in text: BRAF: G596R
PubMed Link: 33318584
Variant Present in the following documents:
  • Main text
  • nihms-1642900.pdf
View BVdb publication page



Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine
Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS
Publication Date: 2021-01

Variant appearance in text: BRAF: G596R
PubMed Link: 33314633
Variant Present in the following documents:
  • CAM4-10-53-s004.xlsx, sheet 1
View BVdb publication page



Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Genes
Śmiech, Magdalena M; Leszczyński, Paweł P; Kono, Hidetoshi H; Wardell, Christopher C; Taniguchi, Hiroaki H
Publication Date: 2020-11-12

Variant appearance in text: BRAF: G596R
PubMed Link: 33198372
Variant Present in the following documents:
  • Main text
  • genes-11-01342.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913361
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: BRAF: G596R
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma.

Ebiomedicine
Sun, Hao H; Liu, Si-Yang SY; Zhou, Jia-Ying JY; Xu, Jin-Tian JT; Zhang, Huang-Kai HK; Yan, Hong-Hong HH; Huan, Jiao-Jiao JJ; Dai, Ping-Ping PP; Xu, Chong-Rui CR; Su, Jian J; Guan, Yan-Fang YF; Yi, Xin X; Yu, Rong-Shan RS; Zhong, Wen-Zhao WZ; Wu, Yi-Long YL
Publication Date: 2020-10

Variant appearance in text: BRAF: 1786G>C; Gly596Arg
PubMed Link: 32927274
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology
Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM
Publication Date: 2018

Variant appearance in text: BRAF: G596R
PubMed Link: 32913992
Variant Present in the following documents:
  • Main text
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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Nature Communications
Pandey, Akhilesh A; Stawiski, Eric W EW; Durinck, Steffen S; Gowda, Harsha H; Goldstein, Leonard D LD; Barbhuiya, Mustafa A MA; Schröder, Markus S MS; Sreenivasamurthy, Sreelakshmi K SK; Kim, Sun-Whe SW; Phalke, Sameer S; Suryamohan, Kushal K; Lee, Kayla K; Chakraborty, Papia P; Kode, Vasumathi V; Shi, Xiaoshan X; Chatterjee, Aditi A; Datta, Keshava K; Khan, Aafaque A AA; Subbannayya, Tejaswini T; Wang, Jing J; Chaudhuri, Subhra S; Gupta, Sanjiv S; Shrivastav, Braj Raj BR; Jaiswal, Bijay S BS; Poojary, Satish S SS; Bhunia, Shushruta S; Garcia, Patricia P; Bizama, Carolina C; Rosa, Lorena L; Kwon, Wooil W; Kim, Hongbeom H; Han, Youngmin Y; Yadav, Thakur Deen TD; Ramprasad, Vedam L VL; Chaudhuri, Amitabha A; Modrusan, Zora Z; Roa, Juan Carlos JC; Tiwari, Pramod Kumar PK; Jang, Jin-Young JY; Seshagiri, Somasekar S
Publication Date: 2020-08-24

Variant appearance in text: BRAF: G596R
PubMed Link: 32839463
Variant Present in the following documents:
  • Main text
  • 41467_2020_17880_MOESM1_ESM.pdf
  • 41467_2020_Article_17880.pdf
  • 41467_2020_17880_MOESM11_ESM.xlsx, sheet 1
  • 41467_2020_17880_MOESM5_ESM.xlsx, sheet 1
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Functional characterization of a PROTAC directed against BRAF mutant V600E.

Nature Chemical Biology
Posternak, Ganna G; Tang, Xiaojing X; Maisonneuve, Pierre P; Jin, Ting T; Lavoie, Hugo H; Daou, Salima S; Orlicky, Stephen S; Goullet de Rugy, Theo T; Caldwell, Lauren L; Chan, Kin K; Aman, Ahmed A; Prakesch, Michael M; Poda, Gennady G; Mader, Pavel P; Wong, Cassandra C; Maier, Stefan S; Kitaygorodsky, Julia J; Larsen, Brett B; Colwill, Karen K; Yin, Zhe Z; Ceccarelli, Derek F DF; Batey, Robert A RA; Taipale, Mikko M; Kurinov, Igor I; Uehling, David D; Wrana, Jeff J; Durocher, Daniel D; Gingras, Anne-Claude AC; Al-Awar, Rima R; Therrien, Marc M; Sicheri, Frank F
Publication Date: 2020-11

Variant appearance in text: BRAF: G596R
PubMed Link: 32778845
Variant Present in the following documents:
  • Main text
View BVdb publication page



Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y
Publication Date: 2020-08-01

Variant appearance in text: BRAF: 1786G>C; G596R
PubMed Link: 32738923
Variant Present in the following documents:
  • 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1
  • 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page