BRAF c.1783T>C ;(p.F595L)

Variant ID: 7-140453152-A-G

NM_004333.4(BRAF):c.1783T>C;(p.F595L)

This variant was identified in 82 publications

View GRCh38 version.




Publications:


Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine
Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M
Publication Date: 2023-04-11

Variant appearance in text: BRAF: F595L
PubMed Link: 37039257
Variant Present in the following documents:
  • Main text
  • CAM4-12-11686.pdf
  • CAM4-12-11686-s002.xlsx, sheet 1
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: F595L
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: BRAF: F595L
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1783T>C; Phe595Leu
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: F595L
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



Infantile epileptic spasms syndrome in children with cardiofaciocutanous syndrome: Clinical presentation and associations with genotype.

American Journal Of Medical Genetics. Part C, Seminars In Medical Genetics
Kenney-Jung, Daniel L DL; Rogers, Dante J DJ; Kroening, Samuel J SJ; Zatkalik, Abigail L AL; Whitmarsh, Ashley E AE; Roberts, Amy E AE; Zenker, Martin M; Gambardella, Maria Luigia ML; Contaldo, Ilaria I; Leoni, Chiara C; Onesimo, Roberta R; Zampino, Giuseppe G; Tartaglia, Marco M; Battaglia, Domenica I DI; Pierpont, Elizabeth I EI
Publication Date: 2022-11-29

Variant appearance in text: BRAF: F595L
PubMed Link: 36448195
Variant Present in the following documents:
  • Main text
  • AJMG-190-501.pdf
View BVdb publication page



Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj
Wagner, Sebastian A SA
Publication Date: 2022

Variant appearance in text: BRAF: F595L
PubMed Link: 36275468
Variant Present in the following documents:
  • peerj-10-14126.pdf
View BVdb publication page



Pan-cancer molecular tumor board experience with biomarker-driven precision immunotherapy.

Npj Precision Oncology
Louie, Bryan H BH; Kato, Shumei S; Kim, Ki Hwan KH; Lim, Hyo Jeong HJ; Okamura, Ryosuke R; Eskander, Ramez N RN; Botta, Gregory G; Patel, Hitendra H; Lee, Suzanna S; Lippman, Scott M SM; Sicklick, Jason K JK; Kurzrock, Razelle R
Publication Date: 2022-09-22

Variant appearance in text: BRAF: F595L
PubMed Link: 36138116
Variant Present in the following documents:
  • 41698_2022_309_MOESM1_ESM.pdf
View BVdb publication page



BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Cancers
Talloa, Dario D; Triarico, Silvia S; Agresti, Pierpaolo P; Mastrangelo, Stefano S; Attinà, Giorgio G; Romano, Alberto A; Maurizi, Palma P; Ruggiero, Antonio A
Publication Date: 2022-08-31

Variant appearance in text: BRAF: F595L
PubMed Link: 36077798
Variant Present in the following documents:
  • cancers-14-04264.pdf
View BVdb publication page



Mutational Profile and Potential Molecular Therapeutic Targets of Pheochromocytoma.

Frontiers In Endocrinology
Ma, Xiaosen X; Ling, Chao C; Zhao, Meng M; Wang, Fen F; Cui, Yunying Y; Wen, Jin J; Ji, Zhigang Z; Zhang, Caili C; Chen, Shi S; Tong, Anli A; Li, Yuxiu Y
Publication Date: 2022

Variant appearance in text: BRAF: F595L
PubMed Link: 35966080
Variant Present in the following documents:
  • Main text
  • Table_1.xlsx, sheet 5
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1783T>C; F595L
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: N/A
PubMed Link: 35835912
Variant Present in the following documents:
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: BRAF: F595L
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies.

Cancer Science
Fukuhara, Suguru S; Oshikawa-Kumade, Yuji Y; Kogure, Yasunori Y; Shingaki, Sumito S; Kariyazono, Hirokazu H; Kikukawa, Yoshiya Y; Koya, Junji J; Saito, Yuki Y; Tabata, Mariko M; Yoshifuji, Kota K; Mizuno, Kota K; Miyagi-Maeshima, Akiko A; Matsushita, Hiromichi H; Sugiyama, Masanaka M; Ogawa, Chitose C; Inamoto, Yoshihiro Y; Fukuda, Takahiro T; Sugano, Masato M; Yamauchi, Nobuhiko N; Minami, Yosuke Y; Hirata, Makoto M; Yoshida, Teruhiko T; Kohno, Takashi T; Kohsaka, Shinji S; Mano, Hiroyuki H; Shiraishi, Yuichi Y; Ogawa, Seishi S; Izutsu, Koji K; Kataoka, Keisuke K
Publication Date: 2022-08

Variant appearance in text: N/A
PubMed Link: 35579198
Variant Present in the following documents:
View BVdb publication page



Deciphering Genetic Alterations of Hairy Cell Leukemia and Hairy Cell Leukemia-like Disorders in 98 Patients.

Cancers
Maitre, Elsa E; Tomowiak, Cécile C; Lebecque, Benjamin B; Bijou, Fontanet F; Benabed, Khaled K; Naguib, Dina D; Kerneves, Pauline P; Cornet, Edouard E; Viailly, Pierre-Julien PJ; Arsham, Jeffrey J; Sola, Brigitte B; Jardin, Fabrice F; Troussard, Xavier X
Publication Date: 2022-04-10

Variant appearance in text: BRAF: F595L
PubMed Link: 35454811
Variant Present in the following documents:
  • Main text
View BVdb publication page



Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)
Zhu, Haichuan H; Dong, Bingjie B; Zhang, Yingchi Y; Wang, Mei M; Rao, Jianan J; Cui, Bowen B; Liu, Yu Y; Jiang, Qian Q; Wang, Weitao W; Yang, Lu L; Yu, Anqi A; Li, Zongru Z; Liu, Chao C; Zhang, Leping L; Huang, Xiaojun X; Zhu, Xiaofan X; Wu, Hong H
Publication Date: 2022-01

Variant appearance in text: BRAF: F595L
PubMed Link: 35399540
Variant Present in the following documents:
  • bls-4-16-s005.xlsx, sheet 2
  • bls-4-16-s005.xlsx, sheet 9
  • bls-4-16-s004.pdf
View BVdb publication page



Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Biochemical Society Transactions
Shevchenko, Ekaterina E; Pantsar, Tatu T
Publication Date: 2022-02-28

Variant appearance in text: BRAF: F595L
PubMed Link: 35226061
Variant Present in the following documents:
  • Main text
  • BST-50-633.pdf
View BVdb publication page



KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers
Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A
Publication Date: 2022-01-28

Variant appearance in text: BRAF: F595L
PubMed Link: 35158933
Variant Present in the following documents:
  • Main text
  • cancers-14-00666.pdf
View BVdb publication page



KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers
Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A
Publication Date: 2022-01-28

Variant appearance in text: BRAF: F595L
PubMed Link: 35158933
Variant Present in the following documents:
  • Main text
  • cancers-14-00666.pdf
View BVdb publication page



Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational Cancer Research
Lei, Lei L; Wang, Wen-Xian WX; Zhu, You-Cai YC; Pu, Xing-Xiang XX; Fang, Yong Y; Wang, Hong H; Zhuang, Wu W; Zhang, Yin-Bin YB; Wang, Li-Ping LP; Xu, Chun-Wei CW; Fang, Mei-Yu MY
Publication Date: 2020-10

Variant appearance in text: BRAF: F595L
PubMed Link: 35117215
Variant Present in the following documents:
  • Main text
  • tcr-09-10-6039.pdf
View BVdb publication page



Mutational landscape of high-grade B-cell lymphoma with MYC-, BCL2 and/or BCL6 rearrangements characterized by whole-exome sequencing.

Haematologica
Künstner, Axel A; Witte, Hanno M HM; Riedl, Jörg J; Bernard, Veronica V; Stölting, Stephanie S; Merz, Hartmut H; Olschewski, Vito V; Peter, Wolfgang W; Ketzer, Julius J; Busch, Yannik Y; Trojok, Peter P; Bubnoff, Nikolas von NV; Busch, Hauke H; Feller, Alfred C AC; Gebauer, Niklas N
Publication Date: 2022-08-01

Variant appearance in text: BRAF: F595L
PubMed Link: 34788985
Variant Present in the following documents:
  • 2021_279631_KUNSTNER_TABS5_SUPPL.xlsx, sheet 1
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: F595L
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Epilepsy and BRAF Mutations: Phenotypes, Natural History and Genotype-Phenotype Correlations.

Genes
Battaglia, Domenica I DI; Gambardella, Maria Luigia ML; Veltri, Stefania S; Contaldo, Ilaria I; Chillemi, Giovanni G; Veredice, Chiara C; Quintiliani, Michela M; Leoni, Chiara C; Onesimo, Roberta R; Verdolotti, Tommaso T; Radio, Francesca Clementina FC; Martinelli, Diego D; Trivisano, Marina M; Specchio, Nicola N; Dravet, Charlotte C; Tartaglia, Marco M; Zampino, Giuseppe G
Publication Date: 2021-08-26

Variant appearance in text: BRAF: Phe595Leu
PubMed Link: 34573299
Variant Present in the following documents:
  • Main text
  • genes-12-01316.pdf
View BVdb publication page



Comprehensive analysis of mutational and clinicopathologic characteristics of poorly differentiated colorectal neuroendocrine carcinomas.

Scientific Reports
Lee, Sun Mi SM; Sung, Chang Ohk CO
Publication Date: 2021-03-18

Variant appearance in text: BRAF: F595L
PubMed Link: 33737597
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_85593.pdf
View BVdb publication page



A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.

Bmc Cancer
Xiao, Jian J; Li, Wenyun W; Huang, Yan Y; Huang, Mengli M; Li, Shanshan S; Zhai, Xiaohui X; Zhao, Jing J; Gao, Chan C; Xie, Wenzhuan W; Qin, Hao H; Cai, Shangli S; Bai, Yuezong Y; Lan, Ping P; Zou, Yifeng Y
Publication Date: 2021-03-16

Variant appearance in text: BRAF: 1783T>C; F595L
PubMed Link: 33726687
Variant Present in the following documents:
  • 12885_2021_7942_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: BRAF: 1783T>C; F595L
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.

Jama Network Open
Zhao, Yiqing Y; Yu, Hanzhong H; Ida, Cris M CM; Halling, Kevin C KC; Kipp, Benjamin R BR; Geiersbach, Katherine K; Rumilla, Kandelaria M KM; Gupta, Sounak S; Lin, Ming-Tseh MT; Zheng, Gang G
Publication Date: 2021-01-04

Variant appearance in text: BRAF: F595L
PubMed Link: 33507258
Variant Present in the following documents:
  • Main text
  • jamanetwopen-e2035479-s001.pdf
View BVdb publication page



BRAF: A Two-Faced Janus.

Cells
Pisapia, Pasquale P; Pepe, Francesco F; Iaccarino, Antonino A; Sgariglia, Roberta R; Nacchio, Mariantonia M; Russo, Gianluca G; Gragnano, Gianluca G; Malapelle, Umberto U; Troncone, Giancarlo G
Publication Date: 2020-11-27

Variant appearance in text: BRAF: F595L
PubMed Link: 33260892
Variant Present in the following documents:
  • Main text
  • cells-09-02549.pdf
View BVdb publication page



Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Genes
Śmiech, Magdalena M; Leszczyński, Paweł P; Kono, Hidetoshi H; Wardell, Christopher C; Taniguchi, Hiroaki H
Publication Date: 2020-11-12

Variant appearance in text: BRAF: F595L
PubMed Link: 33198372
Variant Present in the following documents:
  • Main text
  • genes-11-01342.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs794729219
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: N/A
PubMed Link: 32958805
Variant Present in the following documents:
View BVdb publication page



BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology
Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM
Publication Date: 2018

Variant appearance in text: BRAF: F595L
PubMed Link: 32913992
Variant Present in the following documents:
  • Main text
View BVdb publication page



Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Science Advances
Lee, Sangsin S; Ding, Ning N; Sun, Yidi Y; Yuan, Tanglong T; Li, Jing J; Yuan, Qichen Q; Liu, Lizhong L; Yang, Jie J; Wang, Qian Q; Kolomeisky, Anatoly B AB; Hilton, Isaac B IB; Zuo, Erwei E; Gao, Xue X
Publication Date: 2020-07

Variant appearance in text: BRAF: 1783T>C; Phe595Leu
PubMed Link: 32832622
Variant Present in the following documents:
  • aba1773_Data_file_S1.xlsx, sheet 2
View BVdb publication page



Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.

Biomed Research International
Gutiérrez-Castañeda, Luz D LD; Gamboa, Mauricio M; Nova, John A JA; Pulido, Leonardo L; Tovar-Parra, Jose D JD
Publication Date: 2020

Variant appearance in text: BRAF: Phe595Leu
PubMed Link: 32775409
Variant Present in the following documents:
  • Main text
  • BMRI2020-2046947.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: BRAF: F595L
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



The paradox of cancer genes in non-malignant conditions: implications for precision medicine.

Genome Medicine
Adashek, Jacob J JJ; Kato, Shumei S; Lippman, Scott M SM; Kurzrock, Razelle R
Publication Date: 2020-02-17

Variant appearance in text: BRAF: F595L
PubMed Link: 32066498
Variant Present in the following documents:
  • Main text
  • 13073_2020_Article_714.pdf
View BVdb publication page



Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers.

Nature Communications
Gopal, Priyanka P; Sarihan, Elif Irem EI; Chie, Eui Kyu EK; Kuzmishin, Gwendolyn G; Doken, Semihcan S; Pennell, Nathan A NA; Raymond, Daniel P DP; Murthy, Sudish C SC; Ahmad, Usman U; Raja, Siva S; Almeida, Francisco F; Sethi, Sonali S; Gildea, Thomas R TR; Peacock, Craig D CD; Adams, Drew J DJ; Abazeed, Mohamed E ME
Publication Date: 2019-11-13

Variant appearance in text: BRAF: F595L
PubMed Link: 31723142
Variant Present in the following documents:
  • 41467_2019_Article_13161.pdf
View BVdb publication page



Epigenetic Mechanisms of Escape from BRAF Oncogene Dependency.

Cancers
Khaliq, Mehwish M; Fallahi-Sichani, Mohammad M
Publication Date: 2019-10-01

Variant appearance in text: BRAF: F595L
PubMed Link: 31581557
Variant Present in the following documents:
  • Main text
View BVdb publication page



Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Yaeger, Rona R; Kotani, Daisuke D; Mondaca, Sebastián S; Parikh, Aparna R AR; Bando, Hideaki H; Van Seventer, Emily E EE; Taniguchi, Hiroya H; Zhao, HuiYong H; Thant, Claire N CN; de Stanchina, Elisa E; Rosen, Neal N; Corcoran, Ryan B RB; Yoshino, Takayuki T; Yao, Zhan Z; Ebi, Hiromichi H
Publication Date: 2019-12-01

Variant appearance in text: BRAF: F595L
PubMed Link: 31515458
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Haematologica
Egan, Caoimhe C; Nicolae, Alina A; Lack, Justin J; Chung, Hye-Jung HJ; Skarshaug, Shannon S; Pham, Thu Anh TA; Navarro, Winnifred W; Abdullaev, Zied Z; Aguilera, Nadine S NS; Xi, Liqiang L; Pack, Svetlana S; Pittaluga, Stefania S; Jaffe, Elaine S ES; Raffeld, Mark M
Publication Date: 2020-04

Variant appearance in text: BRAF: F595L
PubMed Link: 31439678
Variant Present in the following documents:
  • Main text
  • 1050951.pdf
View BVdb publication page



Targeting Oncogenic BRAF: Past, Present, and Future.

Cancers
Zaman, Aubhishek A; Wu, Wei W; Bivona, Trever G TG
Publication Date: 2019-08-16

Variant appearance in text: BRAF: F595L
PubMed Link: 31426419
Variant Present in the following documents:
  • Main text
View BVdb publication page



DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients.

Cancers
Mithraprabhu, Sridurga S; Hocking, Jay J; Ramachandran, Malarmathy M; Choi, Kawa K; Klarica, Daniela D; Khong, Tiffany T; Reynolds, John J; Spencer, Andrew A
Publication Date: 2019-06-29

Variant appearance in text: BRAF: F595L
PubMed Link: 31261969
Variant Present in the following documents:
  • cancers-11-00917-s001.xlsx, sheet 2
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: BRAF: F595L
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
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Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: BRAF: F595L
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
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Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.

Journal Of Medicinal Chemistry
Beneker, Chad M CM; Rovoli, Magdalini M; Kontopidis, George G; Röring, Michael M; Galda, Simeon S; Braun, Sandra S; Brummer, Tilman T; McInnes, Campbell C
Publication Date: 2019-04-25

Variant appearance in text: BRAF: F595L
PubMed Link: 30977659
Variant Present in the following documents:
  • Main text
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Langerhans cell histiocytosis in adults: Advances in pathophysiology and treatment.

Cancer Science
Kobayashi, Masayuki M; Tojo, Arinobu A
Publication Date: 2018-12

Variant appearance in text: BRAF: F595L
PubMed Link: 30281871
Variant Present in the following documents:
  • Main text
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Histiocytic cell neoplasms involving the bone marrow: summary of the workshop cases submitted to the 18th Meeting of the European Association for Haematopathology (EAHP) organized by the European Bone Marrow Working Group, Basel 2016.

Annals Of Hematology
Tzankov, Alexandar A; Kremer, Markus M; Leguit, Roos R; Orazi, Attilio A; van der Walt, Jon J; Gianelli, Umberto U; Hebeda, Konnie M KM
Publication Date: 2018-11

Variant appearance in text: BRAF: F595L
PubMed Link: 30084011
Variant Present in the following documents:
  • Main text
  • 277_2018_Article_3436.pdf
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Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology
Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH
Publication Date: 2018-07-31

Variant appearance in text: BRAF: 1783T>C; F595L
PubMed Link: 30064409
Variant Present in the following documents:
  • 12894_2018_380_MOESM1_ESM.xlsx, sheet 1
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Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.

Oncotarget
D'Haene, Nicky N; Fontanges, Quitterie Q; De Nève, Nancy N; Blanchard, Oriane O; Melendez, Barbara B; Delos, Monique M; Dehou, Marie-Françoise MF; Maris, Calliope C; Nagy, Nathalie N; Rousseau, Emmanuel E; Vandenhove, Josse J; Gilles, André A; De Prez, Carine C; Verset, Laurine L; Van Craynest, Marie-Paule MP; Demetter, Pieter P; Van Laethem, Jean-Luc JL; Salmon, Isabelle I; Le Mercier, Marie M
Publication Date: 2018-04-17

Variant appearance in text: BRAF: F595L
PubMed Link: 29755687
Variant Present in the following documents:
  • Main text
  • oncotarget-09-20761.pdf
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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 29698444
Variant Present in the following documents:
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