BRAF c.1781A>T ;(p.D594V)

Variant ID: 7-140453154-T-A

NM_004333.4(BRAF):c.1781A>T;(p.D594V)

This variant was identified in 94 publications

View GRCh38 version.




Publications:


Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: D594V
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: D594V
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj
Wagner, Sebastian A SA
Publication Date: 2022

Variant appearance in text: BRAF: D594V
PubMed Link: 36275468
Variant Present in the following documents:
  • peerj-10-14126.pdf
View BVdb publication page



Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics.

Pathobiology : Journal Of Immunopathology, Molecular And Cellular Biology
Haefliger, Simon S; Marston, Katharina K; Alborelli, Ilaria I; Stauffer, Edouard-Jean EJ; Gugger, Mathias M; Jermann, Philip M PM; Hoeller, Sylvia S; Tornillo, Luigi L; Terracciano, Luigi M LM; Bihl, Michel M; Matter, Matthias S MS
Publication Date: 2022-10-06

Variant appearance in text: BRAF: D594V
PubMed Link: 36202073
Variant Present in the following documents:
  • pat-0090-0166-s01.pdf
View BVdb publication page



Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.

Scientific Reports
Denisova, Oxana V OV; Merisaari, Joni J; Kaur, Amanpreet A; Yetukuri, Laxman L; Jumppanen, Mikael M; von Schantz-Fant, Carina C; Ohlmeyer, Michael M; Wennerberg, Krister K; Aittokallio, Tero T; Taipale, Mikko M; Westermarck, Jukka J
Publication Date: 2022-08-13

Variant appearance in text: BRAF: D594V
PubMed Link: 35963891
Variant Present in the following documents:
  • 41598_2022_18118_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Recognition of BRAF by CDC37 and Re-Evaluation of the Activation Mechanism for the Class 2 BRAF-L597R Mutant.

Biomolecules
Bjorklund, Dennis M DM; Morgan, R Marc L RML; Oberoi, Jasmeen J; Day, Katie L I M KLIM; Galliou, Panagiota A PA; Prodromou, Chrisostomos C
Publication Date: 2022-06-28

Variant appearance in text: BRAF: D594V
PubMed Link: 35883461
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00905.pdf
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: BRAF: D594V
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis.

Cell Death & Disease
Kim, Hyunjoo H; Jeong, Muhah M; Na, Do-Hyeong DH; Ryu, Shin-Hyeon SH; Jeong, Eun Il EI; Jung, Kwangmin K; Kang, Jaemin J; Lee, Ho-June HJ; Sim, Taebo T; Yu, Dae-Yeul DY; Yu, Hee Chul HC; Cho, Baik-Hwan BH; Jung, Yong-Keun YK
Publication Date: 2022-05-18

Variant appearance in text: BRAF: D594V
PubMed Link: 35585049
Variant Present in the following documents:
  • Main text
  • 41419_2022_Article_4921.pdf
View BVdb publication page



Analysis of Genetic Alterations in Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma With Whole-Exome Sequencing.

Frontiers In Oncology
Zhao, Andi A; Wu, Fangtian F; Wang, Yue Y; Li, Jianyong J; Xu, Wei W; Liu, Hu H
Publication Date: 2022

Variant appearance in text: N/A
PubMed Link: 35359413
Variant Present in the following documents:
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: rs121913338
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
View BVdb publication page



Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics
Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B
Publication Date: 2022-05

Variant appearance in text: BRAF: D594V
PubMed Link: 34967917
Variant Present in the following documents:
  • Main text
  • 13353_2021_Article_677.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: D594V
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Yeast as a Tool to Understand the Significance of Human Disease-Associated Gene Variants.

Genes
Cervelli, Tiziana T; Galli, Alvaro A
Publication Date: 2021-08-24

Variant appearance in text: BRAF: D594V
PubMed Link: 34573285
Variant Present in the following documents:
  • Main text
View BVdb publication page



BRAF Mutation Analysis in Primary Acral Melanoma of 41 Cases from South of Iran.

Iranian Journal Of Pathology
Sari Aslani, Fatemeh F; Safaee, Akbar A; Akbarzadeh Jahromi, Mozhgan M; Karami, Leila L
Publication Date: 2021

Variant appearance in text: BRAF: D594V
PubMed Link: 34567185
Variant Present in the following documents:
  • Main text
  • ijp-16-370.pdf
View BVdb publication page



Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: BRAF: D594V
PubMed Link: 34428346
Variant Present in the following documents:
  • Main text
  • MOL2-15-3317.pdf
View BVdb publication page



Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: BRAF: D594V
PubMed Link: 34428346
Variant Present in the following documents:
  • Main text
  • MOL2-15-3317.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.

Jama Network Open
Zhao, Yiqing Y; Yu, Hanzhong H; Ida, Cris M CM; Halling, Kevin C KC; Kipp, Benjamin R BR; Geiersbach, Katherine K; Rumilla, Kandelaria M KM; Gupta, Sounak S; Lin, Ming-Tseh MT; Zheng, Gang G
Publication Date: 2021-01-04

Variant appearance in text: BRAF: D594V
PubMed Link: 33507258
Variant Present in the following documents:
  • jamanetwopen-e2035479-s001.pdf
View BVdb publication page



Clinicopathologic Features and Prognosis of BRAF Mutated Colorectal Cancer Patients.

Frontiers In Oncology
Guan, Wen-Long WL; Qiu, Miao-Zhen MZ; He, Cai-Yun CY; Yang, Li-Qiong LQ; Jin, Ying Y; Wang, Zhi-Qiang ZQ; Li, Yu-Hong YH; Xu, Rui-Hua RH; Wang, Feng-Hua FH
Publication Date: 2020

Variant appearance in text: BRAF: D594V
PubMed Link: 33330032
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913338
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



The genomic landscapes of individual melanocytes from human skin.

Nature
Tang, Jessica J; Fewings, Eleanor E; Chang, Darwin D; Zeng, Hanlin H; Liu, Shanshan S; Jorapur, Aparna A; Belote, Rachel L RL; McNeal, Andrew S AS; Tan, Tuyet M TM; Yeh, Iwei I; Arron, Sarah T ST; Judson-Torres, Robert L RL; Bastian, Boris C BC; Shain, A Hunter AH
Publication Date: 2020-10

Variant appearance in text: N/A
PubMed Link: 33029006
Variant Present in the following documents:
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: BRAF: D594V
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology
Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM
Publication Date: 2018

Variant appearance in text: BRAF: D594V
PubMed Link: 32913992
Variant Present in the following documents:
  • Main text
View BVdb publication page



Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y
Publication Date: 2020-08-01

Variant appearance in text: BRAF: D594V
PubMed Link: 32738923
Variant Present in the following documents:
  • 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



The relationships between systemic cytokine profiles and inflammatory markers in colorectal cancer and the prognostic significance of these parameters.

British Journal Of Cancer
Park, Ji Won JW; Chang, Hee Jin HJ; Yeo, Hyun Yang HY; Han, Nayoung N; Kim, Byung Chang BC; Kong, Sun-Young SY; Kim, Jeongseon J; Oh, Jae Hwan JH
Publication Date: 2020-08

Variant appearance in text: BRAF: D594V
PubMed Link: 32488137
Variant Present in the following documents:
  • 41416_2020_924_MOESM1_ESM.pdf
View BVdb publication page



Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients.

Molecular Oncology
Schneegans, Svenja S; Lück, Lelia L; Besler, Katharina K; Bluhm, Leonie L; Stadler, Julia-Christina JC; Staub, Janina J; Greinert, Rüdiger R; Volkmer, Beate B; Kubista, Mikael M; Gebhardt, Christoffer C; Sartori, Alexander A; Irwin, Darryl D; Serkkola, Elina E; Af Hällström, Taija T; Lianidou, Evi E; Sprenger-Haussels, Markus M; Hussong, Melanie M; Mohr, Peter P; Schneider, Stefan W SW; Shaffer, Jonathan J; Pantel, Klaus K; Wikman, Harriet H
Publication Date: 2020-05

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 32246814
Variant Present in the following documents:
  • MOL2-14-1001-s004.xlsx, sheet 1
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: BRAF: D594V
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
View BVdb publication page



The paradox of cancer genes in non-malignant conditions: implications for precision medicine.

Genome Medicine
Adashek, Jacob J JJ; Kato, Shumei S; Lippman, Scott M SM; Kurzrock, Razelle R
Publication Date: 2020-02-17

Variant appearance in text: BRAF: D594V
PubMed Link: 32066498
Variant Present in the following documents:
  • Main text
  • 13073_2020_Article_714.pdf
View BVdb publication page



Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.

Cancers
Simarro, Javier J; Murria, Rosa R; Pérez-Simó, Gema G; Llop, Marta M; Mancheño, Nuria N; Ramos, David D; Juan, Inmaculada de I; Barragán, Eva E; Laiz, Begoña B; Cases, Enrique E; Ansótegui, Emilio E; Gómez-Codina, José J; Aparicio, Jorge J; Salvador, Carmen C; Juan, Óscar Ó; Palanca, Sarai S
Publication Date: 2019-08-16

Variant appearance in text: BRAF: 1781A>T; Asp594Val
PubMed Link: 31426418
Variant Present in the following documents:
  • cancers-11-01196-s001.pdf
View BVdb publication page



Molecular profile in Paraguayan colorectal cancer patients, towards to a precision medicine strategy.

Cancer Medicine
Fleitas-Kanonnikoff, Tania T; Martinez-Ciarpaglini, Carolina C; Ayala, Josefina J; Gauna, Cinthia C; Denis, Rita R; Yoffe, Ita I; Sforza, Silvia S; Martínez, María Teresa MT; Pomata, Alicia A; Ibarrola-Villava, Maider M; Arevshatyan, Sipan S; Burriel, Verónica V; Boscá, Diego D; Pastor, Oscar O; Ferrer-Martinez, Ana A; Carrasco, Francisca F; Mongort, Cristina C; Navarro, Samuel S; Ribas, Gloria G; Cervantes, Andres A
Publication Date: 2019-06

Variant appearance in text: BRAF: D594V
PubMed Link: 31059199
Variant Present in the following documents:
  • Main text
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: BRAF: D594V
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



RAS Mutation in Mucinous Carcinoma of the Ovary

Asian Pacific Journal Of Cancer Prevention : Apjcp
Panyavaranant, Pinyada P; Teerapakpinyo, Chinachote C; Pohthipornthawat, Natkrita N; Oranratanaphan, Shina S; Shuangshoti, Shanop S; Triratanachat, Surang S
Publication Date: 2019-04-29

Variant appearance in text: BRAF: D594V
PubMed Link: 31030485
Variant Present in the following documents:
  • Main text
  • APJCP-20-1127.pdf
View BVdb publication page



Immune Cell Infiltration of the Primary Tumor, Not PD-L1 Status, Is Associated With Improved Response to Checkpoint Inhibition in Metastatic Melanoma.

Frontiers In Medicine
Kümpers, Christiane C; Jokic, Mladen M; Haase, Ozan O; Offermann, Anne A; Vogel, Wenzel W; Grätz, Victoria V; Langan, Ewan A EA; Perner, Sven S; Terheyden, Patrick P
Publication Date: 2019

Variant appearance in text: BRAF: D594V
PubMed Link: 30931305
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole transcriptome targeted gene quantification provides new insights on pulmonary sarcomatoid carcinomas.

Scientific Reports
Alì, Greta G; Bruno, Rossella R; Poma, Anello Marcello AM; Affinito, Ornella O; Monticelli, Antonella A; Piaggi, Paolo P; Ricciardi, Sara S; Lucchi, Marco M; Melfi, Franca F; Chella, Antonio A; Cocozza, Sergio S; Fontanini, Gabriella G
Publication Date: 2019-03-05

Variant appearance in text: BRAF: D594V
PubMed Link: 30837581
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_40016.pdf
View BVdb publication page



Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology
Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH
Publication Date: 2018-07-31

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 30064409
Variant Present in the following documents:
  • 12894_2018_380_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



The landscape of somatic mutation in sporadic Chinese colorectal cancer.

Oncotarget
Liu, Zhe Z; Yang, Chao C; Li, Xiangchun X; Luo, Wen W; Roy, Bhaskar B; Xiong, Teng T; Zhang, Xiuqing X; Yang, Huanming H; Wang, Jian J; Ye, Zhenhao Z; Chen, Yang Y; Song, Jinghe J; Ma, Shuai S; Zhou, Yong Y; Yang, Min M; Fang, Xiaodong X; Du, Jie J
Publication Date: 2018-06-08

Variant appearance in text: BRAF: 1781A>T; D594V; rs121913338
PubMed Link: 29937994
Variant Present in the following documents:
  • oncotarget-09-27412-s004.xlsx, sheet 1
View BVdb publication page



Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Oncotargets And Therapy
Chen, Qiong Q; Li, Rong R; Zhang, Zhi-Gao ZG; Deng, Qiao-Ting QT; Li, Kun K; Wang, Hao H; Yang, Xue-Xi XX; Wu, Ying-Song YS
Publication Date: 2018

Variant appearance in text: BRAF: D594V
PubMed Link: 29719410
Variant Present in the following documents:
  • Main text
  • ott-11-2279.pdf
View BVdb publication page



Type II RAF inhibitor causes superior ERK pathway suppression compared to type I RAF inhibitor in cells expressing different BRAF mutant types recurrently found in lung cancer.

Oncotarget
Noeparast, Amir A; Giron, Philippe P; De Brakeleer, Sylvia S; Eggermont, Carolien C; De Ridder, Ulrike U; Teugels, Erik E; De Grève, Jacques J
Publication Date: 2018-03-23

Variant appearance in text: BRAF: D594V
PubMed Link: 29662630
Variant Present in the following documents:
  • Main text
  • oncotarget-09-16110.pdf
View BVdb publication page



Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology
Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M
Publication Date: 2018-06-01

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 29659903
Variant Present in the following documents:
  • hyy052supplementaltable1ionver1.xls, sheet 1
View BVdb publication page



Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer.

Oncotarget
Dunne, Philip D PD; Coleman, Helen G HG; Bankhead, Peter P; Alderdice, Matthew M; Gray, Ronan T RT; McQuaid, Stephen S; Bingham, Victoria V; Loughrey, Maurice B MB; James, Jacqueline A JA; McCorry, Amy M B AMB; Gilmore, Alan A; Holohan, Caitriona C; Klingbiel, Dirk D; Tejpar, Sabine S; Johnston, Patrick G PG; McArt, Darragh G DG; Di Nicolantonio, Federica F; Longley, Daniel B DB; Lawler, Mark M
Publication Date: 2018-03-02

Variant appearance in text: BRAF: D594V
PubMed Link: 29568398
Variant Present in the following documents:
  • Main text
  • oncotarget-09-13834.pdf
View BVdb publication page



Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Yu, Helena A HA; Suzawa, Ken K; Jordan, Emmet E; Zehir, Ahmet A; Ni, Ai A; Kim, Ryan R; Kris, Mark G MG; Hellmann, Matthew D MD; Li, Bob T BT; Somwar, Romel R; Solit, David B DB; Berger, Michael F MF; Arcila, Maria M; Riely, Gregory J GJ; Ladanyi, Marc M
Publication Date: 2018-07-01

Variant appearance in text: BRAF: D594V
PubMed Link: 29530932
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting the MAPK Pathway in RAS Mutant Cancers.

Cold Spring Harbor Perspectives In Medicine
Hymowitz, Sarah G SG; Malek, Shiva S
Publication Date: 2018-11-01

Variant appearance in text: BRAF: D594V
PubMed Link: 29440321
Variant Present in the following documents:
  • Main text
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Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Translational Oncology
Lee, Ji Yun JY; Kim, Kyung K; Sung, Hyun Hwan HH; Jeon, Hwang Gyun HG; Jeong, Byong Chang BC; Seo, Seong Il SI; Jeon, Seong Soo SS; Lee, Hyun Moo HM; Choi, Han-Yong HY; Kwon, Ghee-Young GY; Kim, Kyoung-Mee KM; Lee, Jeeyun J; Lim, Ho Yeong HY; Park, Se Hoon SH
Publication Date: 2018-02

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 29161613
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
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Prevalence and detection of low-allele-fraction variants in clinical cancer samples.

Nature Communications
Shin, Hyun-Tae HT; Choi, Yoon-La YL; Yun, Jae Won JW; Kim, Nayoung K D NKD; Kim, Sook-Young SY; Jeon, Hyo Jeong HJ; Nam, Jae-Yong JY; Lee, Chung C; Ryu, Daeun D; Kim, Sang Cheol SC; Park, Kyunghee K; Lee, Eunjin E; Bae, Joon Seol JS; Son, Dae Soon DS; Joung, Je-Gun JG; Lee, Jeeyun J; Kim, Seung Tae ST; Ahn, Myung-Ju MJ; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Lee, Woo Yong WY; Oh, Bo Young BY; Park, Yeon Hee YH; Lee, Jeong Eon JE; Lee, Kwang Hyuk KH; Kim, Hee Cheol HC; Kim, Kyoung-Mee KM; Im, Young-Hyuck YH; Park, Keunchil K; Park, Peter J PJ; Park, Woong-Yang WY
Publication Date: 2017-11-09

Variant appearance in text: BRAF: D594V
PubMed Link: 29123093
Variant Present in the following documents:
  • 41467_2017_1470_MOESM11_ESM.xlsx, sheet 1
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Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.

Oncotarget
Noeparast, Amir A; Teugels, Erik E; Giron, Philippe P; Verschelden, Gil G; De Brakeleer, Sylvia S; Decoster, Lore L; De Grève, Jacques J
Publication Date: 2017-09-01

Variant appearance in text: BRAF: D594V
PubMed Link: 28947956
Variant Present in the following documents:
  • Main text
  • oncotarget-08-60094.pdf
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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: BRAF: D594V; rs121913338
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
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A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer.

Plos One
Inoue, Yoshiaki Y; Shiihara, Jun J; Miyazawa, Hitoshi H; Ohta, Hiromitsu H; Higo, Megumi M; Nagai, Yoshiaki Y; Kobayashi, Kunihiko K; Saijo, Yasuo Y; Tsuchida, Masanori M; Nakayama, Mitsuo M; Hagiwara, Koichi K
Publication Date: 2017

Variant appearance in text: BRAF: D594V
PubMed Link: 28448556
Variant Present in the following documents:
  • Main text
  • pone.0176525.pdf
  • pone.0176525.s006.xlsx, sheet 1
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Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.

Molecular Oncology
Polosukhina, Dina D; Love, Harold D HD; Correa, Hernan H; Su, Zengliu Z; Dahlman, Kimberly B KB; Pao, William W; Moses, Harold L HL; Arteaga, Carlos L CL; Lovvorn, Harold N HN; Zent, Roy R; Clark, Peter E PE
Publication Date: 2017-04

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 28188683
Variant Present in the following documents:
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
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Molecular genetics of thyroid cancer.

Genetics Research
Rebaї, Maha M; Rebaї, Ahmed A
Publication Date: 2016-05-13

Variant appearance in text: BRAF: Asp594Val
PubMed Link: 27174043
Variant Present in the following documents:
  • Main text
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Prognostic Role of BRAF Mutation in Stage II/III Colorectal Cancer Receiving Curative Resection and Adjuvant Chemotherapy: A Meta-Analysis Based on Randomized Clinical Trials.

Plos One
Zhu, Lizhen L; Dong, Caixia C; Cao, Ying Y; Fang, Xuefeng X; Zhong, Chenhan C; Li, Dan D; Yuan, Ying Y
Publication Date: 2016

Variant appearance in text: BRAF: D594V
PubMed Link: 27138801
Variant Present in the following documents:
  • Main text
  • pone.0154795.pdf
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Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Oncotarget
Xu, Naiqing N; Fang, Wenfeng W; Mu, Libing L; Tang, Yanna Y; Gao, Lei L; Ren, Shengxiang S; Cao, Dengfeng D; Zhou, Lixin L; Zhang, Aiqun A; Liu, Deruo D; Zhou, Caicun C; Wong, Kwok-Kin KK; Yu, Lei L; Zhang, Li L; Chen, Liang L
Publication Date: 2016-01-26

Variant appearance in text: BRAF: D594V
PubMed Link: 26646697
Variant Present in the following documents:
  • oncotarget-07-3884-s001.pdf
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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Oncotarget
Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH
Publication Date: 2015-12-22

Variant appearance in text: BRAF: 1781A>T; D594V
PubMed Link: 26527317
Variant Present in the following documents:
  • oncotarget-06-43731-s002.xlsx, sheet 1
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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2015-12

Variant appearance in text: BRAF: D594V
PubMed Link: 26502337
Variant Present in the following documents:
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2
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Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.

Bmc Cancer
Zheng, Gang G; Tseng, Li-Hui LH; Chen, Guoli G; Haley, Lisa L; Illei, Peter P; Gocke, Christopher D CD; Eshleman, James R JR; Lin, Ming-Tseh MT
Publication Date: 2015-10-24

Variant appearance in text: BRAF: D594V
PubMed Link: 26498038
Variant Present in the following documents:
  • Main text
View BVdb publication page