Publications:

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Association of BRAF Variants With Disease Characteristics, Prognosis, and Targeted Therapy Response in Intrahepatic Cholangiocarcinoma.

Jama Network Open

Xin, Hao-Yang HY; Sun, Rong-Qi RQ; Zou, Ji-Xue JX; Wang, Peng-Cheng PC; Wang, Jia-Yin JY; Ye, Yu-Hang YH; Liu, Kai-Xuan KX; Hu, Zhi-Qiang ZQ; Zhou, Zheng-Jun ZJ; Fan, Jia J; Zhou, Jian J; Zhou, Shao-Lai SL

Publication Date: 2023-03-01

Variant appearance in text: BRAF: D594A

PubMed Link: 36867406

Variant Present in the following documents:

• jamanetwopen-e231476-s001.pdf

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: BRAF: D594A

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1781A>C; Asp594Ala

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica

Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z

Publication Date: 2022-12-30

Variant appearance in text: BRAF: D594A

PubMed Link: 36799315

Variant Present in the following documents:

• AMA-51-217.pdf

View BVdb publication page

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Characterization of proteome-size scaling by integrative omics reveals mechanisms of proliferation control in cancer.

Science Advances

Jones, Ian I; Dent, Lucas L; Higo, Tomoaki T; Roumeliotis, Theodoros T; Arias Garcia, Maria M; Shree, Hansa H; Choudhary, Jyoti J; Pedersen, Malin M; Bakal, Chris C

Publication Date: 2023-01-25

Variant appearance in text: BRAF: D594A

PubMed Link: 36696495

Variant Present in the following documents:

• Main text
• sciadv.add0636.pdf

View BVdb publication page

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Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj

Wagner, Sebastian A SA

Publication Date: 2022

Variant appearance in text: BRAF: D594A

PubMed Link: 36275468

Variant Present in the following documents:

• peerj-10-14126.pdf

View BVdb publication page

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Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis.

Molecular Cancer

Renaud, Emilie E; Riegel, Kristina K; Romero, Rossana R; Suryamohan, Kushal K; Distler, Ute U; Tenzer, Stefan S; Schad, Arno A; Musholt, Thomas J TJ; Rajalingam, Krishnaraj K

Publication Date: 2022-10-10

Variant appearance in text: BRAF: D594A

PubMed Link: 36217175

Variant Present in the following documents:

• Main text
• 12943_2022_1665_MOESM1_ESM.pdf
• 12943_2022_Article_1665.pdf

View BVdb publication page

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Correlation of plasma cell assessment by phenotypic methods and molecular profiles by NGS in patients with plasma cell dyscrasias.

Bmc Medical Genomics

Rebmann Chigrinova, Ekaterina E; Porret, Naomi A NA; Andres, Martin M; Wiedemann, Gertrud G; Banz, Yara Y; Legros, Myriam M; Pollak, Matthias M; Oppliger Leibundgut, Elisabeth E; Pabst, Thomas T; Bacher, Ulrike U

Publication Date: 2022-09-23

Variant appearance in text: BRAF: D594A

PubMed Link: 36138464

Variant Present in the following documents:

• Main text
• 12920_2022_Article_1346.pdf

View BVdb publication page

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BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Cancers

Talloa, Dario D; Triarico, Silvia S; Agresti, Pierpaolo P; Mastrangelo, Stefano S; Attinà, Giorgio G; Romano, Alberto A; Maurizi, Palma P; Ruggiero, Antonio A

Publication Date: 2022-08-31

Variant appearance in text: BRAF: D594A

PubMed Link: 36077798

Variant Present in the following documents:

• cancers-14-04264.pdf

View BVdb publication page

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Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.

Leukemia

Jahn, Nikolaus N; Jahn, Ekaterina E; Saadati, Maral M; Bullinger, Lars L; Larson, Richard A RA; Ottone, Tiziana T; Amadori, Sergio S; Prior, Thomas W TW; Brandwein, Joseph M JM; Appelbaum, Frederick R FR; Medeiros, Bruno C BC; Tallman, Martin S MS; Ehninger, Gerhard G; Heuser, Michael M; Ganser, Arnold A; Pallaud, Celine C; Gathmann, Insa I; Krzykalla, Julia J; Benner, Axel A; Bloomfield, Clara D CD; Thiede, Christian C; Stone, Richard M RM; Döhner, Hartmut H; Döhner, Konstanze K

Publication Date: 2022-09

Variant appearance in text: BRAF: D594A

PubMed Link: 35922444

Variant Present in the following documents:

• 41375_2022_1650_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Genome Medicine

Wang, Meng M; Banik, Ishani I; Shain, A Hunter AH; Yeh, Iwei I; Bastian, Boris C BC

Publication Date: 2022-06-16

Variant appearance in text: BRAF: D594A

PubMed Link: 35706047

Variant Present in the following documents:

• 13073_2022_1068_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.

Nature Communications

Murphy, Brandon M BM; Terrell, Elizabeth M EM; Chirasani, Venkat R VR; Weiss, Tirzah J TJ; Lew, Rachel E RE; Holderbaum, Andrea M AM; Dhakal, Aastha A; Posada, Valentina V; Fort, Marie M; Bodnar, Michael S MS; Carey, Leiah M LM; Chen, Min M; Burd, Craig J CJ; Coppola, Vincenzo V; Morrison, Deborah K DK; Campbell, Sharon L SL; Burd, Christin E CE

Publication Date: 2022-06-07

Variant appearance in text: BRAF: D594A

PubMed Link: 35672316

Variant Present in the following documents:

• 41467_2022_30881_MOESM2_ESM.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: BRAF: 1781A>C; D594A

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Application of an Ultrasensitive NGS-Based Blood Test for the Diagnosis of Early-Stage Lung Cancer: Sensitivity, a Hurdle Still Difficult to Overcome.

Cancers

Van der Linden, Malaïka M; Van Gaever, Bram B; Raman, Lennart L; Vermaelen, Karim K; Demedts, Ingel I; Surmont, Veerle V; Himpe, Ulrike U; Lievens, Yolande Y; Ferdinande, Liesbeth L; Dedeurwaerdere, Franceska F; Van der Meulen, Joni J; Claes, Kathleen K; Menten, Björn B; Van Dorpe, Jo J

Publication Date: 2022-04-18

Variant appearance in text: BRAF: 1781A>C; Asp594Ala

PubMed Link: 35454937

Variant Present in the following documents:

• cancers-14-02031.pdf

View BVdb publication page

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Analysis of Genetic Alterations in Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma With Whole-Exome Sequencing.

Frontiers In Oncology

Zhao, Andi A; Wu, Fangtian F; Wang, Yue Y; Li, Jianyong J; Xu, Wei W; Liu, Hu H

Publication Date: 2022

Variant appearance in text: N/A

PubMed Link: 35359413

Variant Present in the following documents:

View BVdb publication page

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KSR induces RAS-independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors.

Molecular Oncology

Paniagua, Guillem G; Jacob, Harrys K C HKC; Brehey, Oksana O; García-Alonso, Sara S; Lechuga, Carmen G CG; Pons, Tirso T; Musteanu, Monica M; Guerra, Carmen C; Drosten, Matthias M; Barbacid, Mariano M

Publication Date: 2022-09

Variant appearance in text: BRAF: D594A

PubMed Link: 35313064

Variant Present in the following documents:

• Main text
• MOL2-16-3066.pdf

View BVdb publication page

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: BRAF: D594A

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12
• PCMR-35-369-s003.xlsx, sheet 6

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: BRAF: Asp594Ala

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression.

International Journal Of Molecular Sciences

Śmiech, Magdalena M; Leszczyński, Paweł P; Wardell, Christopher C; Poznański, Piotr P; Pierzchała, Mariusz M; Taniguchi, Hiroaki H

Publication Date: 2022-01-28

Variant appearance in text: BRAF: D594A

PubMed Link: 35163468

Variant Present in the following documents:

• Main text
• ijms-23-01548.pdf

View BVdb publication page

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Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression.

International Journal Of Molecular Sciences

Śmiech, Magdalena M; Leszczyński, Paweł P; Wardell, Christopher C; Poznański, Piotr P; Pierzchała, Mariusz M; Taniguchi, Hiroaki H

Publication Date: 2022-01-28

Variant appearance in text: BRAF: D594A

PubMed Link: 35163468

Variant Present in the following documents:

• Main text
• ijms-23-01548.pdf

View BVdb publication page

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Mutational profiling of melanomas in patients from the southeast coast of China.

Translational Cancer Research

Zheng, Ai-Wen AW; Jia, Dong-Dong DD; Zhou, Cheng-Cheng CC; Li, Tao T

Publication Date: 2020-08

Variant appearance in text: BRAF: D594A

PubMed Link: 35117841

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational Cancer Research

Lei, Lei L; Wang, Wen-Xian WX; Zhu, You-Cai YC; Pu, Xing-Xiang XX; Fang, Yong Y; Wang, Hong H; Zhuang, Wu W; Zhang, Yin-Bin YB; Wang, Li-Ping LP; Xu, Chun-Wei CW; Fang, Mei-Yu MY

Publication Date: 2020-10

Variant appearance in text: BRAF: D594A

PubMed Link: 35117215

Variant Present in the following documents:

• Main text
• tcr-09-10-6039.pdf

View BVdb publication page

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Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics

Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B

Publication Date: 2022-05

Variant appearance in text: BRAF: D594A

PubMed Link: 34967917

Variant Present in the following documents:

• Main text
• 13353_2021_Article_677.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: BRAF: D594A

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.

Jama Network Open

Zhao, Yiqing Y; Yu, Hanzhong H; Ida, Cris M CM; Halling, Kevin C KC; Kipp, Benjamin R BR; Geiersbach, Katherine K; Rumilla, Kandelaria M KM; Gupta, Sounak S; Lin, Ming-Tseh MT; Zheng, Gang G

Publication Date: 2021-01-04

Variant appearance in text: BRAF: D594A

PubMed Link: 33507258

Variant Present in the following documents:

• jamanetwopen-e2035479-s001.pdf

View BVdb publication page

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BRAF: A Two-Faced Janus.

Cells

Pisapia, Pasquale P; Pepe, Francesco F; Iaccarino, Antonino A; Sgariglia, Roberta R; Nacchio, Mariantonia M; Russo, Gianluca G; Gragnano, Gianluca G; Malapelle, Umberto U; Troncone, Giancarlo G

Publication Date: 2020-11-27

Variant appearance in text: BRAF: D594A

PubMed Link: 33260892

Variant Present in the following documents:

• Main text
• cells-09-02549.pdf

View BVdb publication page

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Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Genes

Śmiech, Magdalena M; Leszczyński, Paweł P; Kono, Hidetoshi H; Wardell, Christopher C; Taniguchi, Hiroaki H

Publication Date: 2020-11-12

Variant appearance in text: BRAF: D594A

PubMed Link: 33198372

Variant Present in the following documents:

• Main text
• genes-11-01342.pdf

View BVdb publication page

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Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity.

Nature Communications

Newell, Felicity F; Wilmott, James S JS; Johansson, Peter A PA; Nones, Katia K; Addala, Venkateswar V; Mukhopadhyay, Pamela P; Broit, Natasa N; Amato, Carol M CM; Van Gulick, Robert R; Kazakoff, Stephen H SH; Patch, Ann-Marie AM; Koufariotis, Lambros T LT; Lakis, Vanessa V; Leonard, Conrad C; Wood, Scott S; Holmes, Oliver O; Xu, Qinying Q; Lewis, Karl K; Medina, Theresa T; Gonzalez, Rene R; Saw, Robyn P M RPM; Spillane, Andrew J AJ; Stretch, Jonathan R JR; Rawson, Robert V RV; Ferguson, Peter M PM; Dodds, Tristan J TJ; Thompson, John F JF; Long, Georgina V GV; Levesque, Mitchell P MP; Robinson, William A WA; Pearson, John V JV; Mann, Graham J GJ; Scolyer, Richard A RA; Waddell, Nicola N; Hayward, Nicholas K NK

Publication Date: 2020-10-16

Variant appearance in text: BRAF: 1781A>C; Asp594Ala

PubMed Link: 33067454

Variant Present in the following documents:

• 41467_2020_18988_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs121913338

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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The genomic landscapes of individual melanocytes from human skin.

Nature

Tang, Jessica J; Fewings, Eleanor E; Chang, Darwin D; Zeng, Hanlin H; Liu, Shanshan S; Jorapur, Aparna A; Belote, Rachel L RL; McNeal, Andrew S AS; Tan, Tuyet M TM; Yeh, Iwei I; Arron, Sarah T ST; Judson-Torres, Robert L RL; Bastian, Boris C BC; Shain, A Hunter AH

Publication Date: 2020-10

Variant appearance in text: BRAF: D594A; rs121913338

PubMed Link: 33029006

Variant Present in the following documents:

• NIHMS1626314-supplement-1626314_SuppTable3.xlsx, sheet 1
• NIHMS1626314-supplement-1626314_SuppTable3.xlsx, sheet 2

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: BRAF: D594A

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology

Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM

Publication Date: 2018

Variant appearance in text: BRAF: D594A

PubMed Link: 32913992

Variant Present in the following documents:

• Main text

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: BRAF: D594A

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study.

Cancer Science

Yasuda, Takahiko T; Sanada, Masashi M; Nishijima, Dai D; Kanamori, Takashi T; Iijima, Yuka Y; Hattori, Hiroyoshi H; Saito, Akiko A; Miyoshi, Hiroaki H; Ishikawa, Yuichi Y; Asou, Norio N; Usuki, Kensuke K; Hirabayashi, Shinsuke S; Kato, Motohiro M; Ri, Masaki M; Handa, Hiroshi H; Ishida, Tadao T; Shibayama, Hirohiko H; Abe, Masahiro M; Iriyama, Chisako C; Karube, Kennosuke K; Nishikori, Momoko M; Ohshima, Koichi K; Kataoka, Keisuke K; Yoshida, Kenichi K; Shiraishi, Yuichi Y; Goto, Hiroaki H; Adachi, Souichi S; Kobayashi, Ryoji R; Kiyoi, Hitoshi H; Miyazaki, Yasushi Y; Ogawa, Seishi S; Kurahashi, Hiroki H; Yokoyama, Hisayuki H; Manabe, Atsushi A; Iida, Shinsuke S; Tomita, Akihiro A; Horibe, Keizo K

Publication Date: 2020-09

Variant appearance in text: BRAF: D594A

PubMed Link: 32619037

Variant Present in the following documents:

• CAS-111-3367-s004.xlsx, sheet 4

View BVdb publication page

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TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients.

Journal Of Experimental & Clinical Cancer Research : Cr

Dinami, Roberto R; Porru, Manuela M; Amoreo, Carla Azzurra CA; Sperduti, Isabella I; Mottolese, Marcella M; Buglioni, Simonetta S; Marinelli, Daniele D; Maugeri-Saccà, Marcello M; Sacconi, Andrea A; Blandino, Giovanni G; Leonetti, Carlo C; Di Rocco, Giuliana G; Verdina, Alessandra A; Spinella, Francesca F; Fiorentino, Francesco F; Ciliberto, Gennaro G; Biroccio, Annamaria A; Zizza, Pasquale P

Publication Date: 2020-06-15

Variant appearance in text: BRAF: D594A

PubMed Link: 32539869

Variant Present in the following documents:

• 13046_2020_1612_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer

Mack, Philip C PC; Banks, Kimberly C KC; Espenschied, Carin R CR; Burich, Rebekah A RA; Zill, Oliver A OA; Lee, Christine E CE; Riess, Jonathan W JW; Mortimer, Stefanie A SA; Talasaz, AmirAli A; Lanman, Richard B RB; Gandara, David R DR

Publication Date: 2020-07-15

Variant appearance in text: BRAF: D594A

PubMed Link: 32365229

Variant Present in the following documents:

• Main text
• CNCR-126-3219.pdf

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: BRAF: D594A

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling.

The Journal Of Biological Chemistry

Cope, Nicholas J NJ; Novak, Borna B; Liu, Zhiwei Z; Cavallo, Maria M; Gunderwala, Amber Y AY; Connolly, Matthew M; Wang, Zhihong Z

Publication Date: 2020-02-21

Variant appearance in text: BRAF: D594A

PubMed Link: 31929109

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeting Oncogenic BRAF: Past, Present, and Future.

Cancers

Zaman, Aubhishek A; Wu, Wei W; Bivona, Trever G TG

Publication Date: 2019-08-16

Variant appearance in text: BRAF: D594A

PubMed Link: 31426419

Variant Present in the following documents:

• Main text
• cancers-11-01197.pdf

View BVdb publication page

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Atypical BRAF and NRAS Mutations in Mucosal Melanoma.

Cancers

Dumaz, Nicolas N; Jouenne, Fanélie F; Delyon, Julie J; Mourah, Samia S; Bensussan, Armand A; Lebbé, Céleste C

Publication Date: 2019-08-08

Variant appearance in text: BRAF: D594A

PubMed Link: 31398831

Variant Present in the following documents:

• Main text
• cancers-11-01133.pdf

View BVdb publication page

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DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients.

Cancers

Mithraprabhu, Sridurga S; Hocking, Jay J; Ramachandran, Malarmathy M; Choi, Kawa K; Klarica, Daniela D; Khong, Tiffany T; Reynolds, John J; Spencer, Andrew A

Publication Date: 2019-06-29

Variant appearance in text: BRAF: D594A

PubMed Link: 31261969

Variant Present in the following documents:

• cancers-11-00917-s001.xlsx, sheet 2

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: BRAF: D594A

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.

Journal Of Medicinal Chemistry

Beneker, Chad M CM; Rovoli, Magdalini M; Kontopidis, George G; Röring, Michael M; Galda, Simeon S; Braun, Sandra S; Brummer, Tilman T; McInnes, Campbell C

Publication Date: 2019-04-25

Variant appearance in text: BRAF: D594A

PubMed Link: 30977659

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RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell-cell junctions.

The Febs Journal

Dorard, Coralie C; Cseh, Botond B; Ehrenreiter, Karin K; Wimmer, Reiner R; Varga, Andrea A; Hirschmugl, Tatjana T; Maier, Barbara B; Kramer, Karina K; Fürlinger, Sabine S; Doma, Eszter E; Baccarini, Manuela M

Publication Date: 2019-06

Variant appearance in text: BRAF: D594A

PubMed Link: 30828992

Variant Present in the following documents:

• Main text
• FEBS-286-2277.pdf

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Hybrid Capture-Based Genomic Profiling Identifies BRAF V600 and Non-V600 Alterations in Melanoma Samples Negative by Prior Testing.

The Oncologist

Boussemart, Lise L; Nelson, Annie A; Wong, Michael M; Ross, Jeffrey S JS; Sosman, Jeffrey J; Mehnert, Janice J; Daniels, Gregory G; Kendra, Kari K; Ali, Siraj Mahamed SM; Miller, Vincent A VA; Schrock, Alexa B AB

Publication Date: 2019-05

Variant appearance in text: BRAF: D594A

PubMed Link: 30683711

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The atypical MAPK ERK3 potently suppresses melanoma cell growth and invasiveness.

Journal Of Cellular Physiology

Chen, Minyi M; Myers, Amanda K AK; Markey, Michael P MP; Long, Weiwen W

Publication Date: 2019-08

Variant appearance in text: BRAF: D594A

PubMed Link: 30569573

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Biology and treatment of BRAF mutant metastatic melanoma.

Melanoma Management

Kong, Benjamin Y BY; Carlino, Matteo S MS; Menzies, Alexander M AM

Publication Date: 2016-03

Variant appearance in text: BRAF: D594A

PubMed Link: 30190871

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Exome-wide somatic mutation characterization of small bowel adenocarcinoma.

Plos Genetics

Hänninen, Ulrika A UA; Katainen, Riku R; Tanskanen, Tomas T; Plaketti, Roosa-Maria RM; Laine, Riku R; Hamberg, Jiri J; Ristimäki, Ari A; Pukkala, Eero E; Taipale, Minna M; Mecklin, Jukka-Pekka JP; Forsström, Linda M LM; Pitkänen, Esa E; Palin, Kimmo K; Välimäki, Niko N; Mäkinen, Netta N; Aaltonen, Lauri A LA

Publication Date: 2018-03

Variant appearance in text: BRAF: D594A

PubMed Link: 29522538

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• pgen.1007200.pdf

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Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.

Oncotarget

Noeparast, Amir A; Teugels, Erik E; Giron, Philippe P; Verschelden, Gil G; De Brakeleer, Sylvia S; Decoster, Lore L; De Grève, Jacques J

Publication Date: 2017-09-01

Variant appearance in text: BRAF: D594A

PubMed Link: 28947956

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• oncotarget-08-60094.pdf

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A Braf kinase-inactive mutant induces lung adenocarcinoma.

Nature

Nieto, Patricia P; Ambrogio, Chiara C; Esteban-Burgos, Laura L; Gómez-López, Gonzalo G; Blasco, María Teresa MT; Yao, Zhan Z; Marais, Richard R; Rosen, Neal N; Chiarle, Roberto R; Pisano, David G DG; Barbacid, Mariano M; Santamaría, David D

Publication Date: 2017-08-10

Variant appearance in text: BRAF: D594A

PubMed Link: 28783725

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Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Nature

Yao, Zhan Z; Yaeger, Rona R; Rodrik-Outmezguine, Vanessa S VS; Tao, Anthony A; Torres, Neilawattie M NM; Chang, Matthew T MT; Drosten, Matthias M; Zhao, Huiyong H; Cecchi, Fabiola F; Hembrough, Todd T; Michels, Judith J; Baumert, Hervé H; Miles, Linde L; Campbell, Naomi M NM; de Stanchina, Elisa E; Solit, David B DB; Barbacid, Mariano M; Taylor, Barry S BS; Rosen, Neal N

Publication Date: 2017-08-10

Variant appearance in text: BRAF: D594A

PubMed Link: 28783719

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Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation.

Oncogenesis

Xu, J J; Pfarr, N N; Endris, V V; Mai, E K EK; Md Hanafiah, N H NH; Lehners, N N; Penzel, R R; Weichert, W W; Ho, A D AD; Schirmacher, P P; Goldschmidt, H H; Andrulis, M M; Raab, M S MS

Publication Date: 2017-05-15

Variant appearance in text: BRAF: D594A

PubMed Link: 28504689

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• oncsis201736a.pdf

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