Publications:

Predicting Anticancer Drug Resistance Mediated by Mutations.

Pharmaceuticals (Basel, Switzerland)

Lin, Yu-Feng YF; Liu, Jia-Jun JJ; Chang, Yu-Jen YJ; Yu, Chin-Sheng CS; Yi, Wei W; Lane, Hsien-Yuan HY; Lu, Chih-Hao CH

Publication Date: 2022-01-24

Variant appearance in text: BRAF: F516L

PubMed Link: 35215249

Variant Present in the following documents:

• Main text
• pharmaceuticals-15-00136.pdf

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Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

The Journal Of Pathology

Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I

Publication Date: 2018-07

Variant appearance in text: BRAF: 1546T>C; F516L

PubMed Link: 29604063

Variant Present in the following documents:

• PATH-245-283-s021.xlsx, sheet 1

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Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation.

Angewandte Chemie (International Ed. In English)

Jambrina, Pablo G PG; Rauch, Nora N; Pilkington, Ruth R; Rybakova, Katja K; Nguyen, Lan K LK; Kholodenko, Boris N BN; Buchete, Nicolae-Viorel NV; Kolch, Walter W; Rosta, Edina E

Publication Date: 2016-01-18

Variant appearance in text: BRAF: F516L

PubMed Link: 26644280

Variant Present in the following documents:

• Main text
• ANIE-55-983.pdf
• ANIE-55-983-s001.pdf

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