Publications:

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Response and resistance to BRAFV600E inhibition in gliomas: Roadblocks ahead?

Frontiers In Oncology

Capogiri, Monica M; De Micheli, Andrea J AJ; Lassaletta, Alvaro A; Muñoz, Denise P DP; Coppé, Jean-Philippe JP; Mueller, Sabine S; Guerreiro Stucklin, Ana S AS

Publication Date: 2022

Variant appearance in text: BRAF: L514V

PubMed Link: 36698391

Variant Present in the following documents:

• Main text

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Resistance mechanisms in BRAFV600E paediatric high-grade glioma and current therapeutic approaches.

Frontiers In Oncology

Lehmann, R R; Rayner, B S BS; Ziegler, D S DS

Publication Date: 2022

Variant appearance in text: BRAF: L514V

PubMed Link: 36582791

Variant Present in the following documents:

• Main text

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Drug resistance in targeted cancer therapies with RAF inhibitors.

Cancer Drug Resistance (Alhambra, Calif.)

Degirmenci, Ufuk U; Yap, Jiajun J; Sim, Yuen Rong M YRM; Qin, Shiru S; Hu, Jiancheng J

Publication Date: 2021

Variant appearance in text: BRAF: L514V

PubMed Link: 35582307

Variant Present in the following documents:

• cdr-4-665.pdf

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Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAFV600E-Mutant Human Glioma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Schreck, Karisa C KC; Morin, Andrew A; Zhao, Guisheng G; Allen, Amy N AN; Flannery, Patrick P; Glantz, Michael M; Green, Adam L AL; Jones, Chris C; Jones, Kenneth L KL; Kilburn, Lindsay B LB; Nazemi, Kellie J KJ; Samuel, David D; Sanford, Bridget B; Solomon, David A DA; Wang, Jiawan J; Pratilas, Christine A CA; Nicolaides, Theodore T; Mulcahy Levy, Jean M JM

Publication Date: 2021-11-15

Variant appearance in text: BRAF: L514V

PubMed Link: 34433654

Variant Present in the following documents:

• Main text
• 6197.pdf

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Clinical Implications of Acquired BRAF Inhibitors Resistance in Melanoma.

International Journal Of Molecular Sciences

Savoia, Paola P; Zavattaro, Elisa E; Cremona, Ottavio O

Publication Date: 2020-12-20

Variant appearance in text: BRAF: L514V

PubMed Link: 33419275

Variant Present in the following documents:

• Main text

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Targeted Therapy in Melanoma and Mechanisms of Resistance.

International Journal Of Molecular Sciences

Czarnecka, Anna M AM; Bartnik, Ewa E; Fiedorowicz, Michał M; Rutkowski, Piotr P

Publication Date: 2020-06-27

Variant appearance in text: BRAF: L514V

PubMed Link: 32605090

Variant Present in the following documents:

• Main text
• ijms-21-04576.pdf

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CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma.

Genomics, Proteomics & Bioinformatics

Li, Ziyi Z; Wang, Binbin B; Gu, Shengqing S; Jiang, Peng P; Sahu, Avinash A; Chen, Chen-Hao CH; Han, Tong T; Shi, Sailing S; Wang, Xiaoqing X; Traugh, Nicole N; Liu, Hailing H; Liu, Yin Y; Wu, Qiu Q; Brown, Myles M; Xiao, Tengfei T; Boland, Genevieve M GM; Shirley Liu, X X

Publication Date: 2020-02

Variant appearance in text: BRAF: L514V

PubMed Link: 32413516

Variant Present in the following documents:

• Main text
• main.pdf

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Challenges of targeting BRAF V600E mutations in adult primary brain tumor patients: a report of two cases.

Cns Oncology

Smith-Cohn, Matthew M; Davidson, Christian C; Colman, Howard H; Cohen, Adam L AL

Publication Date: 2019-12-01

Variant appearance in text: BRAF: L514V

PubMed Link: 31818130

Variant Present in the following documents:

• Main text
• cns-08-48.pdf

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A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.

Cancer Discovery

Wang, Jiawan J; Yao, Zhan Z; Jonsson, Philip P; Allen, Amy N AN; Qin, Alice Can Ran ACR; Uddin, Sharmeen S; Dunkel, Ira J IJ; Petriccione, Mary M; Manova, Katia K; Haque, Sofia S; Rosenblum, Marc K MK; Pisapia, David J DJ; Rosen, Neal N; Taylor, Barry S BS; Pratilas, Christine A CA

Publication Date: 2018-09

Variant appearance in text: BRAF: L514V

PubMed Link: 29880583

Variant Present in the following documents:

• Main text

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Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.

Acs Chemical Biology

Xie, Peng P; Williams, Douglas S DS; Atilla-Gokcumen, G Ekin GE; Milk, Leslie L; Xiao, Min M; Smalley, Keiran S M KS; Herlyn, Meenhard M; Meggers, Eric E; Marmorstein, Ronen R

Publication Date: 2008-05-16

Variant appearance in text: BRAF: L514V

PubMed Link: 18484710

Variant Present in the following documents:

• Main text

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