BRAF c.1522A>G ;(p.T508A)

Variant ID: 7-140476884-T-C

NM_004333.4(BRAF):c.1522A>G;(p.T508A)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp
Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC
Publication Date: 2021

Variant appearance in text: BRAF: T508A
PubMed Link: 34673281
Variant Present in the following documents:
  • mmc2.xlsx, sheet 3
View BVdb publication page



Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp
Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC
Publication Date: 2021-10-19

Variant appearance in text: BRAF: T508A
PubMed Link: 34673281
Variant Present in the following documents:
  • mmc2.xlsx, sheet 3
View BVdb publication page



A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.

Bmc Cancer
Xiao, Jian J; Li, Wenyun W; Huang, Yan Y; Huang, Mengli M; Li, Shanshan S; Zhai, Xiaohui X; Zhao, Jing J; Gao, Chan C; Xie, Wenzhuan W; Qin, Hao H; Cai, Shangli S; Bai, Yuezong Y; Lan, Ping P; Zou, Yifeng Y
Publication Date: 2021-03-16

Variant appearance in text: BRAF: 1522A>G; T508A
PubMed Link: 33726687
Variant Present in the following documents:
  • 12885_2021_7942_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: BRAF: 1522A>G; T508A
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy.

Theranostics
von Baumgarten, Louisa L; Kumbrink, Jörg J; Jung, Andreas A; Reischer, Anna A; Flach, Madeleine M; Liebmann, Sibylle S; Metzeler, Klaus H KH; Holch, Julian W JW; Niyazi, Maximilian M; Thon, Niklas N; Straube, Andreas A; von Bergwelt-Baildon, Michael M; Heinemann, Volker V; Kirchner, Thomas T; Westphalen, Christoph Benedikt CB
Publication Date: 2020

Variant appearance in text: BRAF: 1522A>G; Thr508Ala
PubMed Link: 31903155
Variant Present in the following documents:
  • thnov10p0856s1.pdf
View BVdb publication page



Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.

Journal Of Medicinal Chemistry
Beneker, Chad M CM; Rovoli, Magdalini M; Kontopidis, George G; Röring, Michael M; Galda, Simeon S; Braun, Sandra S; Brummer, Tilman T; McInnes, Campbell C
Publication Date: 2019-04-25

Variant appearance in text: BRAF: T508A
PubMed Link: 30977659
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: BRAF: 1522A>G
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Repositioning organohalogen drugs: a case study for identification of potent B-Raf V600E inhibitors via docking and bioassay.

Scientific Reports
Li, Yisu Y; Guo, Binbin B; Xu, Zhijian Z; Li, Bo B; Cai, Tingting T; Zhang, Xinben X; Yu, Yuqi Y; Wang, Heyao H; Shi, Jiye J; Zhu, Weiliang W
Publication Date: 2016-08-09

Variant appearance in text: BRAF: T508A
PubMed Link: 27501852
Variant Present in the following documents:
  • Main text
  • srep31074.pdf
View BVdb publication page