BRAF c.1460T>C ;(p.V487A)

Variant ID: 7-140477848-A-G

NM_004333.4(BRAF):c.1460T>C;(p.V487A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Chemically modified MIR143-3p exhibited anti-cancer effects by impairing the KRAS network in colorectal cancer cells.

Molecular Therapy. Nucleic Acids
Sugito, Nobuhiko N; Heishima, Kazuki K; Akao, Yukihiro Y
Publication Date: 2022-12-13

Variant appearance in text: BRAF: V487A
PubMed Link: 36189421
Variant Present in the following documents:
  • Main text
  • mmc2.pdf
  • main.pdf
View BVdb publication page



Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.

Molecular And Cellular Biology
Wu, Pui-Kei PK; Hong, Seung-Keun SK; Park, Jong-In JI
Publication Date: 2017-09-15

Variant appearance in text: BRAF: V487A
PubMed Link: 28674184
Variant Present in the following documents:
  • Main text
View BVdb publication page



The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.

Elife
Kiel, Christina C; Benisty, Hannah H; Lloréns-Rico, Veronica V; Serrano, Luis L
Publication Date: 2016-01-08

Variant appearance in text: BRAF: V487A
PubMed Link: 26744778
Variant Present in the following documents:
  • elife-12814-supp1.xlsx, sheet 2
View BVdb publication page