BRAF c.1351G>A ;(p.E451K)

Variant ID: 7-140481457-C-T

NM_004333.4(BRAF):c.1351G>A;(p.E451K)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Epigenetic Regulation in Gastroenteropancreatic Neuroendocrine Tumors.

Frontiers In Oncology
Crabtree, Judy S JS
Publication Date: 2022

Variant appearance in text: BRAF: E451K
PubMed Link: 35747820
Variant Present in the following documents:
  • Main text
  • fonc-12-901435.pdf
View BVdb publication page



Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
Xiang, Chan C; Ji, Chunyu C; Cai, Yiran Y; Teng, Haohua H; Wang, Yulu Y; Zhao, Ruiying R; Shang, Zhanxian Z; Guo, Lianying L; Chen, Shengnan S; Lizaso, Analyn A; Lin, Jing J; Wang, Haozhe H; Li, Bing B; Zhang, Zhou Z; Zhao, Jikai J; Wei, Jinzhi J; Liu, Jiaxin J; Zhu, Lei L; Fang, Wentao W; Han, Yuchen Y
Publication Date: 2022-09

Variant appearance in text: BRAF: E451K
PubMed Link: 35641658
Variant Present in the following documents:
  • 41379_2022_1076_MOESM1_ESM.pdf
View BVdb publication page



Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition.

Plos One
Allen, Amy A; Qin, Alice Can Ran ACR; Raj, Nitya N; Wang, Jiawan J; Uddin, Sharmeen S; Yao, Zhan Z; Tang, Laura L; Meyers, Paul A PA; Taylor, Barry S BS; Berger, Michael F MF; Yaeger, Rona R; Reidy-Lagunes, Diane D; Pratilas, Christine A CA
Publication Date: 2019

Variant appearance in text: BRAF: E451K
PubMed Link: 31158244
Variant Present in the following documents:
  • Main text
  • pone.0217399.pdf
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Real-Time Genomic Characterization of Metastatic Pancreatic Neuroendocrine Tumors Has Prognostic Implications and Identifies Potential Germline Actionability.

Jco Precision Oncology
Raj, Nitya N; Shah, Ronak R; Stadler, Zsofia Z; Mukherjee, Semanti S; Chou, Joanne J; Untch, Brian B; Li, Janet J; Kelly, Virginia V; Saltz, Leonard B LB; Mandelker, Diana D; Ladanyi, Marc M; Berger, Michael F MF; Klimstra, David S DS; Reidy-Lagunes, Diane D; Osoba, Muyinat M
Publication Date: 2018

Variant appearance in text: BRAF: E451K
PubMed Link: 30687805
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: BRAF: E451K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
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Distinct molecular profile of diffuse cerebellar gliomas.

Acta Neuropathologica
Nomura, Masashi M; Mukasa, Akitake A; Nagae, Genta G; Yamamoto, Shogo S; Tatsuno, Kenji K; Ueda, Hiroki H; Fukuda, Shiro S; Umeda, Takayoshi T; Suzuki, Tomonari T; Otani, Ryohei R; Kobayashi, Keiichi K; Maruyama, Takashi T; Tanaka, Shota S; Takayanagi, Shunsaku S; Nejo, Takahide T; Takahashi, Satoshi S; Ichimura, Koichi K; Nakamura, Taishi T; Muragaki, Yoshihiro Y; Narita, Yoshitaka Y; Nagane, Motoo M; Ueki, Keisuke K; Nishikawa, Ryo R; Shibahara, Junji J; Aburatani, Hiroyuki H; Saito, Nobuhito N
Publication Date: 2017-12

Variant appearance in text: BRAF: E451K
PubMed Link: 28852847
Variant Present in the following documents:
  • Main text
  • 401_2017_Article_1771.pdf
View BVdb publication page