Publications:

N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide (TAK632) Promotes Inhibition of BRAF through the Induction of Inhibited Dimers.

Journal Of Medicinal Chemistry

Grasso, Michael M; Estrada, Michelle A MA; Berrios, Kiara N KN; Winkler, Jeffrey D JD; Marmorstein, Ronen R

Publication Date: 2018-06-14

Variant appearance in text: BRAF: W450A

PubMed Link: 29727562

Variant Present in the following documents:

• Main text

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Allosteric activation of functionally asymmetric RAF kinase dimers.

Cell

Hu, Jiancheng J; Stites, Edward C EC; Yu, Haiyang H; Germino, Elizabeth A EA; Meharena, Hiruy S HS; Stork, Philip J S PJS; Kornev, Alexandr P AP; Taylor, Susan S SS; Shaw, Andrey S AS

Publication Date: 2013-08-29

Variant appearance in text: BRAF: W450A

PubMed Link: 23993095

Variant Present in the following documents:

• Main text

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