Publications:

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: BRAF: D287H

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5

View BVdb publication page

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Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica

Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z

Publication Date: 2022-12-30

Variant appearance in text: BRAF: D287H

PubMed Link: 36799315

Variant Present in the following documents:

• AMA-51-217.pdf

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BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Cancers

Talloa, Dario D; Triarico, Silvia S; Agresti, Pierpaolo P; Mastrangelo, Stefano S; Attinà, Giorgio G; Romano, Alberto A; Maurizi, Palma P; Ruggiero, Antonio A

Publication Date: 2022-08-31

Variant appearance in text: BRAF: D287H

PubMed Link: 36077798

Variant Present in the following documents:

• cancers-14-04264.pdf

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Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational Cancer Research

Lei, Lei L; Wang, Wen-Xian WX; Zhu, You-Cai YC; Pu, Xing-Xiang XX; Fang, Yong Y; Wang, Hong H; Zhuang, Wu W; Zhang, Yin-Bin YB; Wang, Li-Ping LP; Xu, Chun-Wei CW; Fang, Mei-Yu MY

Publication Date: 2020-10

Variant appearance in text: BRAF: D287H

PubMed Link: 35117215

Variant Present in the following documents:

• Main text
• tcr-09-10-6039.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: BRAF: D287H

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Identification of Prognostic Biomarker Candidates Associated With Melanoma Using High-Dimensional Genomic Data.

Frontiers In Genetics

Kutt, Brody B; Burdorf, Rachel R; Bain, Travaughn T; Cameron, Nicardo N; Pearah, Alexia A; Subasi, Ersoy E; Carroll, David J DJ; Moore, Lisa K LK; Subasi, Munevver Mine MM

Publication Date: 2021

Variant appearance in text: BRAF: D287H

PubMed Link: 34589115

Variant Present in the following documents:

• Main text
• fgene-12-707105.pdf

View BVdb publication page

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Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Nature Communications

Vandekerkhove, Gillian G; Lavoie, Jean-Michel JM; Annala, Matti M; Murtha, Andrew J AJ; Sundahl, Nora N; Walz, Simon S; Sano, Takeshi T; Taavitsainen, Sinja S; Ritch, Elie E; Fazli, Ladan L; Hurtado-Coll, Antonio A; Wang, Gang G; Nykter, Matti M; Black, Peter C PC; Todenhöfer, Tilman T; Ost, Piet P; Gibb, Ewan A EA; Chi, Kim N KN; Eigl, Bernhard J BJ; Wyatt, Alexander W AW

Publication Date: 2021-01-08

Variant appearance in text: BRAF: D287H

PubMed Link: 33420073

Variant Present in the following documents:

• 41467_2020_20493_MOESM3_ESM.xlsx, sheet 4
• 41467_2020_20493_MOESM3_ESM.xlsx, sheet 7

View BVdb publication page

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BRAF: A Two-Faced Janus.

Cells

Pisapia, Pasquale P; Pepe, Francesco F; Iaccarino, Antonino A; Sgariglia, Roberta R; Nacchio, Mariantonia M; Russo, Gianluca G; Gragnano, Gianluca G; Malapelle, Umberto U; Troncone, Giancarlo G

Publication Date: 2020-11-27

Variant appearance in text: BRAF: D287H

PubMed Link: 33260892

Variant Present in the following documents:

• Main text
• cells-09-02549.pdf

View BVdb publication page

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Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.

Pigment Cell & Melanoma Research

Christodoulou, Eirini E; Rashid, Mamunur M; Pacini, Clare C; Droop, Alastair A; Robertson, Holly H; Groningen, Tim van TV; Teunisse, Amina F A S AFAS; Iorio, Francesco F; Jochemsen, Aart G AG; Adams, David J DJ; Doorn, Remco van RV

Publication Date: 2021-01

Variant appearance in text: BRAF: D287H

PubMed Link: 32767816

Variant Present in the following documents:

• PCMR-34-122-s006.xlsx, sheet 1

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: BRAF: D287H

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.

Nature Communications

Sale, Matthew J MJ; Minihane, Emma E; Monks, Noel R NR; Gilley, Rebecca R; Richards, Frances M FM; Schifferli, Kevin P KP; Andersen, Courtney L CL; Davies, Emma J EJ; Vicente, Mario Aladren MA; Ozono, Eiko E; Markovets, Aleksandra A; Dry, Jonathan R JR; Drew, Lisa L; Flemington, Vikki V; Proia, Theresa T; Jodrell, Duncan I DI; Smith, Paul D PD; Cook, Simon J SJ

Publication Date: 2019-11-14

Variant appearance in text: BRAF: D287H

PubMed Link: 31727888

Variant Present in the following documents:

• 41467_2019_12409_MOESM1_ESM.pdf

View BVdb publication page

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Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.

Nature Communications

Reitman, Zachary J ZJ; Paolella, Brenton R BR; Bergthold, Guillaume G; Pelton, Kristine K; Becker, Sarah S; Jones, Robert R; Sinai, Claire E CE; Malkin, Hayley H; Huang, Ying Y; Grimmet, Leslie L; Herbert, Zachary T ZT; Sun, Yu Y; Weatherbee, Jessica L JL; Alberta, John A JA; Daley, John F JF; Rozenblatt-Rosen, Orit O; Condurat, Alexandra L AL; Qian, Kenin K; Khadka, Prasidda P; Segal, Rosalind A RA; Haas-Kogan, Daphne D; Filbin, Mariella G MG; Suva, Mario L ML; Regev, Aviv A; Stiles, Charles D CD; Kieran, Mark W MW; Goumnerova, Liliana L; Ligon, Keith L KL; Shalek, Alex K AK; Bandopadhayay, Pratiti P; Beroukhim, Rameen R

Publication Date: 2019-08-19

Variant appearance in text: BRAF: 859G>C

PubMed Link: 31427603

Variant Present in the following documents:

• 41467_2019_11493_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Targeting Oncogenic BRAF: Past, Present, and Future.

Cancers

Zaman, Aubhishek A; Wu, Wei W; Bivona, Trever G TG

Publication Date: 2019-08-16

Variant appearance in text: BRAF: D287H

PubMed Link: 31426419

Variant Present in the following documents:

• Main text
• cancers-11-01197.pdf

View BVdb publication page

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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Nature Communications

Menden, Michael P MP; Wang, Dennis D; Mason, Mike J MJ; Szalai, Bence B; Bulusu, Krishna C KC; Guan, Yuanfang Y; Yu, Thomas T; Kang, Jaewoo J; Jeon, Minji M; Wolfinger, Russ R; Nguyen, Tin T; Zaslavskiy, Mikhail M; , ; Jang, In Sock IS; Ghazoui, Zara Z; Ahsen, Mehmet Eren ME; Vogel, Robert R; Neto, Elias Chaibub EC; Norman, Thea T; Tang, Eric K Y EKY; Garnett, Mathew J MJ; Veroli, Giovanni Y Di GYD; Fawell, Stephen S; Stolovitzky, Gustavo G; Guinney, Justin J; Dry, Jonathan R JR; Saez-Rodriguez, Julio J

Publication Date: 2019-06-17

Variant appearance in text: BRAF: D287H

PubMed Link: 31209238

Variant Present in the following documents:

• 41467_2019_9799_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: BRAF: 859G>C

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-6.xlsx, sheet 1
• NIHMS958974-supplement-5.xlsx, sheet 1

View BVdb publication page

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Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Nature

Yao, Zhan Z; Yaeger, Rona R; Rodrik-Outmezguine, Vanessa S VS; Tao, Anthony A; Torres, Neilawattie M NM; Chang, Matthew T MT; Drosten, Matthias M; Zhao, Huiyong H; Cecchi, Fabiola F; Hembrough, Todd T; Michels, Judith J; Baumert, Hervé H; Miles, Linde L; Campbell, Naomi M NM; de Stanchina, Elisa E; Solit, David B DB; Barbacid, Mariano M; Taylor, Barry S BS; Rosen, Neal N

Publication Date: 2017-08-10

Variant appearance in text: BRAF: D287H

PubMed Link: 28783719

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: BRAF: 859G>C; D287H

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

View BVdb publication page

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BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition.

Cancer Cell

Yao, Zhan Z; Torres, Neilawattie M NM; Tao, Anthony A; Gao, Yijun Y; Luo, Lusong L; Li, Qi Q; de Stanchina, Elisa E; Abdel-Wahab, Omar O; Solit, David B DB; Poulikakos, Poulikos I PI; Rosen, Neal N

Publication Date: 2015-09-14

Variant appearance in text: BRAF: D287H

PubMed Link: 26343582

Variant Present in the following documents:

• Main text

View BVdb publication page

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