Publications:

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Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer.

Molecular Biomedicine

Ruan, Hang H; Leibowitz, Brian J BJ; Peng, Yingpeng Y; Shen, Lin L; Chen, Lujia L; Kuang, Charlie C; Schoen, Robert E RE; Lu, Xinghua X; Zhang, Lin L; Yu, Jian J

Publication Date: 2022-03-21

Variant appearance in text: BRAF: D211G

PubMed Link: 35307764

Variant Present in the following documents:

• 43556_2022_70_MOESM1_ESM.pdf

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Establishment and characterization of a new human colon cancer cell line, PUMC-CRC1.

Scientific Reports

Bian, Xiaocui X; Cao, Fang F; Wang, Xiaowan X; Hou, Yuhong Y; Zhao, Haitao H; Liu, Yuqin Y

Publication Date: 2021-06-23

Variant appearance in text: BRAF: D211G

PubMed Link: 34162944

Variant Present in the following documents:

• Main text
• 41598_2021_Article_92491.pdf

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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment.

Molecules (Basel, Switzerland)

Zoetemelk, Marloes M; Ramzy, George M GM; Rausch, Magdalena M; Nowak-Sliwinska, Patrycja P

Publication Date: 2020-06-04

Variant appearance in text: BRAF: D211G

PubMed Link: 32512790

Variant Present in the following documents:

• Main text
• molecules-25-02614.pdf

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NUDT7 Loss Promotes Kras CRC Development.

Cancers

Song, Jinsoo J; Park, Sujeong S; Oh, Jinjoo J; Kim, Deokha D; Ryu, Ji Hyun JH; Park, Won Cheol WC; Baek, In-Jeoung IJ; Cheng, Xi X; Lu, Xin X; Jin, Eun-Jung EJ

Publication Date: 2020-03-02

Variant appearance in text: BRAF: D211G

PubMed Link: 32131398

Variant Present in the following documents:

• cancers-12-00576-s001.pdf

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Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

Genome Medicine

Rospo, Giuseppe G; Lorenzato, Annalisa A; Amirouchene-Angelozzi, Nabil N; Magrì, Alessandro A; Cancelliere, Carlotta C; Corti, Giorgio G; Negrino, Carola C; Amodio, Vito V; Montone, Monica M; Bartolini, Alice A; Barault, Ludovic L; Novara, Luca L; Isella, Claudio C; Medico, Enzo E; Bertotti, Andrea A; Trusolino, Livio L; Germano, Giovanni G; Di Nicolantonio, Federica F; Bardelli, Alberto A

Publication Date: 2019-06-28

Variant appearance in text: BRAF: D211G

PubMed Link: 31253177

Variant Present in the following documents:

• 13073_2019_654_MOESM2_ESM.xlsx, sheet 39

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Mutation Hotspots in the β-Catenin Gene: Lessons from the Human Cancer Genome Databases.

Molecules And Cells

Kim, Sewoon S; Jeong, Sunjoo S

Publication Date: 2019-01-31

Variant appearance in text: BRAF: D211G

PubMed Link: 30699286

Variant Present in the following documents:

• Main text
• molce-42-1-8.pdf

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Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin.

Scientific Reports

Narvi, Elli E; Vaparanta, Katri K; Karrila, Anna A; Chakroborty, Deepankar D; Knuutila, Sakari S; Pulliainen, Arto A; Sundvall, Maria M; Elenius, Klaus K

Publication Date: 2018-11-08

Variant appearance in text: BRAF: Asp211Gly

PubMed Link: 30410004

Variant Present in the following documents:

• Main text
• 41598_2018_Article_34938.pdf

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Macrophage migration inhibitory factor promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells.

Molecular Oncology

Cheon, Seul-Ki SK; Kim, Hwang-Phill HP; Park, Ye-Lim YL; Jang, Jee-Eun JE; Lim, Yoojoo Y; Song, Sang-Hyun SH; Han, Sae-Won SW; Kim, Tae-You TY

Publication Date: 2018-08

Variant appearance in text: BRAF: D211G

PubMed Link: 29896883

Variant Present in the following documents:

• MOL2-12-1398-s001.pdf

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Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: BRAF: 632A>G

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-6.xlsx, sheet 1
• NIHMS958974-supplement-5.xlsx, sheet 1

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Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.

Molecular Cancer

Berg, Kaja C G KCG; Eide, Peter W PW; Eilertsen, Ina A IA; Johannessen, Bjarne B; Bruun, Jarle J; Danielsen, Stine A SA; Bjørnslett, Merete M; Meza-Zepeda, Leonardo A LA; Eknæs, Mette M; Lind, Guro E GE; Myklebost, Ola O; Skotheim, Rolf I RI; Sveen, Anita A; Lothe, Ragnhild A RA

Publication Date: 2017-07-06

Variant appearance in text: BRAF: D211G

PubMed Link: 28683746

Variant Present in the following documents:

• Main text
• 12943_2017_Article_691.pdf
• 12943_2017_691_MOESM1_ESM.xlsx, sheet 5

View BVdb publication page

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BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method.

Genes & Development

Lim, Chae-Seok CS; Kang, Xi X; Mirabella, Vincent V; Zhang, Huaye H; Bu, Qian Q; Araki, Yoichi Y; Hoang, Elizabeth T ET; Wang, Shiqiang S; Shen, Ying Y; Choi, Sukwoo S; Kaang, Bong-Kiun BK; Chang, Qiang Q; Pang, Zhiping P ZP; Huganir, Richard L RL; Zhu, J Julius JJ

Publication Date: 2017-03-15

Variant appearance in text: BRAF: D211G

PubMed Link: 28404629

Variant Present in the following documents:

• supp_31.6.537_Supplemental_Materials.pdf

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: BRAF: 632A>G; D211G

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor.

Plos One

Dumble, Melissa M; Crouthamel, Ming-Chih MC; Zhang, Shu-Yun SY; Schaber, Michael M; Levy, Dana D; Robell, Kimberly K; Liu, Qi Q; Figueroa, David J DJ; Minthorn, Elisabeth A EA; Seefeld, Mark A MA; Rouse, Meagan B MB; Rabindran, Sridhar K SK; Heerding, Dirk A DA; Kumar, Rakesh R

Publication Date: 2014

Variant appearance in text: BRAF: D211G

PubMed Link: 24978597

Variant Present in the following documents:

• pone.0100880.s006.xlsx, sheet 1

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