An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Vidimar, Vania V; Beilhartz, Greg L GL; Park, Minyoung M; Biancucci, Marco M; Kieffer, Matthew B MB; Gius, David R DR; Melnyk, Roman A RA; Satchell, Karla J F KJF
A highly recurrent RPS27 5'UTR mutation in melanoma.
Oncotarget
Dutton-Regester, Ken K; Gartner, Jared J JJ; Emmanuel, Rafi R; Qutob, Nouar N; Davies, Michael A MA; Gershenwald, Jeffrey E JE; Robinson, William W; Robinson, Steven S; Rosenberg, Steven A SA; Scolyer, Richard A RA; Mann, Graham J GJ; Thompson, John F JF; Hayward, Nicholas K NK; Samuels, Yardena Y