BRAF c.85_86delinsCA ;(p.A29H)

Variant ID: 7-140624418-GC-TG

NM_004333.4(BRAF):c.85_86delinsCA;(p.A29H)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Landscape of Genetic Alterations Underlying Hallmark Signature Changes in Cancer Reveals TP53 Aneuploidy-driven Metabolic Reprogramming.

Cancer Research Communications
McClure, Marni B MB; Kogure, Yasunori Y; Ansari-Pour, Naser N; Saito, Yuki Y; Chao, Hann-Hsiang HH; Shepherd, Jonathan J; Tabata, Mariko M; Olopade, Olufunmilayo I OI; Wedge, David C DC; Hoadley, Katherine A KA; Perou, Charles M CM; Kataoka, Keisuke K
Publication Date: 2023-02

Variant appearance in text: BRAF: A29H
PubMed Link: 36860655
Variant Present in the following documents:
  • crc-22-0073-s01.xlsx, sheet 2
View BVdb publication page



Decoding molecular programs in melanoma brain metastases.

Nature Communications
Radke, Josefine J; Schumann, Elisa E; Onken, Julia J; Koll, Randi R; Acker, Güliz G; Bodnar, Bohdan B; Senger, Carolin C; Tierling, Sascha S; Möbs, Markus M; Vajkoczy, Peter P; Vidal, Anna A; Högler, Sandra S; Kodajova, Petra P; Westphal, Dana D; Meier, Friedegund F; Heppner, Frank F; Kreuzer-Redmer, Susanne S; Grebien, Florian F; Jürchott, Karsten K; Redmer, Torben T
Publication Date: 2022-11-26

Variant appearance in text: BRAF: A29H
PubMed Link: 36435874
Variant Present in the following documents:
  • 41467_2022_34899_MOESM18_ESM.xlsx, sheet 24
  • 41467_2022_34899_MOESM18_ESM.xlsx, sheet 34
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: BRAF: A29H
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology
Georgoulias, George G; Zaravinos, Apostolos A
Publication Date: 2022

Variant appearance in text: BRAF: A29H
PubMed Link: 36389735
Variant Present in the following documents:
  • Table_7.xlsx, sheet 8
View BVdb publication page



Two subtypes of cutaneous melanoma with distinct mutational signatures and clinico-genomic characteristics.

Frontiers In Genetics
Kim, Yoon-Seob YS; Lee, Minho M; Chung, Yeun-Jun YJ
Publication Date: 2022

Variant appearance in text: BRAF: A29H
PubMed Link: 36246650
Variant Present in the following documents:
  • DataSheet2.xlsx, sheet 3
View BVdb publication page



Exploring Tumor Immune Microenvironment and Its Associations With Molecular Characteristics in Melanoma.

Frontiers In Oncology
Wang, Jiangyuan J; Peng, Cong C; Dai, Wentao W; Chen, Xiang X; Meng, Jing J; Jiang, Taijiao T
Publication Date: 2022

Variant appearance in text: BRAF: A29H
PubMed Link: 35530341
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



Chromosomal copy number heterogeneity predicts survival rates across cancers.

Nature Communications
van Dijk, Erik E; van den Bosch, Tom T; Lenos, Kristiaan J KJ; El Makrini, Khalid K; Nijman, Lisanne E LE; van Essen, Hendrik F B HFB; Lansu, Nico N; Boekhout, Michiel M; Hageman, Joris H JH; Fitzgerald, Rebecca C RC; Punt, Cornelis J A CJA; Tuynman, Jurriaan B JB; Snippert, Hugo J G HJG; Kops, Geert J P L GJPL; Medema, Jan Paul JP; Ylstra, Bauke B; Vermeulen, Louis L; Miedema, Daniël M DM
Publication Date: 2021-05-27

Variant appearance in text: BRAF: A29H
PubMed Link: 34045449
Variant Present in the following documents:
  • 41467_2021_23384_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics
Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM
Publication Date: 2020-12

Variant appearance in text: BRAF: A29H
PubMed Link: 33230298
Variant Present in the following documents:
  • NIHMS1637640-supplement-SuppData1.xlsx, sheet 1
View BVdb publication page



Prognostic value of B cells in cutaneous melanoma.

Genome Medicine
Selitsky, Sara R SR; Mose, Lisle E LE; Smith, Christof C CC; Chai, Shengjie S; Hoadley, Katherine A KA; Dittmer, Dirk P DP; Moschos, Stergios J SJ; Parker, Joel S JS; Vincent, Benjamin G BG
Publication Date: 2019-05-28

Variant appearance in text: BRAF: A29H
PubMed Link: 31138334
Variant Present in the following documents:
  • 13073_2019_647_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Interplay between small and long non-coding RNAs in cutaneous melanoma: a complex jigsaw puzzle with missing pieces.

Molecular Oncology
Riefolo, Mattia M; Porcellini, Elisa E; Dika, Emi E; Broseghini, Elisabetta E; Ferracin, Manuela M
Publication Date: 2019-01

Variant appearance in text: BRAF: A29H
PubMed Link: 30499222
Variant Present in the following documents:
  • MOL2-13-74.pdf
View BVdb publication page



Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Publication Date: 2018-07-27

Variant appearance in text: BRAF: A29H
PubMed Link: 30053901
Variant Present in the following documents:
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 19
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.

Scientific Reports
Qutob, Nouar N; Masuho, Ikuo I; Alon, Michal M; Emmanuel, Rafi R; Cohen, Isadora I; Di Pizio, Antonella A; Madore, Jason J; Elkahloun, Abdel A; Ziv, Tamar T; Levy, Ronen R; Gartner, Jared J JJ; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Greenberg, Polina P; Brodezki, Alexandra A; Rosenberg, Steven A SA; Kosloff, Mickey M; Hayward, Nicholas K NK; Admon, Arie A; Niv, Masha Y MY; Scolyer, Richard A RA; Martemyanov, Kirill A KA; Samuels, Yardena Y
Publication Date: 2018-01-12

Variant appearance in text: BRAF: A29H
PubMed Link: 29330521
Variant Present in the following documents:
  • 41598_2017_18851_MOESM3_ESM.xlsx, sheet 1
  • 41598_2017_18851_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Npj Genomic Medicine
Madubata, Chioma J CJ; Roshan-Ghias, Alireza A; Chu, Timothy T; Resnick, Samuel S; Zhao, Junfei J; Arnes, Luis L; Wang, Jiguang J; Rabadan, Raul R
Publication Date: 2017

Variant appearance in text: BRAF: A29H
PubMed Link: 29263839
Variant Present in the following documents:
  • 41525_2017_32_MOESM8_ESM.xlsx, sheet 6
View BVdb publication page



Mutation Clusters from Cancer Exome.

Genes
Kakushadze, Zura Z; Yu, Willie W
Publication Date: 2017-08-15

Variant appearance in text: BRAF: A29H
PubMed Link: 28809811
Variant Present in the following documents:
  • genes-08-00201.pdf
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: BRAF: A29H
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2015-12

Variant appearance in text: BRAF: A29H
PubMed Link: 26502337
Variant Present in the following documents:
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2
  • NIHMS65345-supplement-Supplementary_table_1.xlsx, sheet 1
View BVdb publication page