BRAF c.78G>C ;(p.E26D)

Variant ID: 7-140624426-C-G

NM_004333.4(BRAF):c.78G>C;(p.E26D)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.

Jama Network Open
Zhao, Yiqing Y; Yu, Hanzhong H; Ida, Cris M CM; Halling, Kevin C KC; Kipp, Benjamin R BR; Geiersbach, Katherine K; Rumilla, Kandelaria M KM; Gupta, Sounak S; Lin, Ming-Tseh MT; Zheng, Gang G
Publication Date: 2021-01-04

Variant appearance in text: BRAF: E26D
PubMed Link: 33507258
Variant Present in the following documents:
  • Main text
  • jamanetwopen-e2035479-s001.pdf
View BVdb publication page



Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Zhao, Ming M; Scott, Stephen S; Evans, Kurt W KW; Yuca, Erkan E; Saridogan, Turcin T; Zheng, Xiaofeng X; Wang, Heping H; Korkut, Anil A; Cruz Pico, Christian X CX; Demirhan, Mehmet M; Kirby, Bryce B; Kopetz, Scott S; Diala, Irmina I; Lalani, Alshad S AS; Piha-Paul, Sarina S; Meric-Bernstam, Funda F
Publication Date: 2021-03-15

Variant appearance in text: BRAF: E26D
PubMed Link: 33414137
Variant Present in the following documents:
  • Main text
View BVdb publication page



Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.

Gastroenterology
Fischer, Catherine G CG; Beleva Guthrie, Violeta V; Braxton, Alicia M AM; Zheng, Lily L; Wang, Pei P; Song, Qianqian Q; Griffin, James F JF; Chianchiano, Peter E PE; Hosoda, Waki W; Niknafs, Noushin N; Springer, Simeon S; Dal Molin, Marco M; Masica, David D; Scharpf, Robert B RB; Thompson, Elizabeth D ED; He, Jin J; Wolfgang, Christopher L CL; Hruban, Ralph H RH; Roberts, Nicholas J NJ; Lennon, Anne Marie AM; Jiao, Yuchen Y; Karchin, Rachel R; Wood, Laura D LD
Publication Date: 2019-10

Variant appearance in text: BRAF: E26D
PubMed Link: 31175866
Variant Present in the following documents:
  • Main text
View BVdb publication page



CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer.

Bmc Cancer
Zhao, Zi-Ming ZM; Yost, Susan E SE; Hutchinson, Katherine E KE; Li, Sierra Min SM; Yuan, Yate-Ching YC; Noorbakhsh, Javad J; Liu, Zheng Z; Warden, Charles C; Johnson, Radia M RM; Wu, Xiwei X; Chuang, Jeffrey H JH; Yuan, Yuan Y
Publication Date: 2019-01-21

Variant appearance in text: BRAF: E26D
PubMed Link: 30665374
Variant Present in the following documents:
  • 12885_2019_5290_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Deleterious coding variants in multi-case families with non-syndromic cleft lip and/or palate phenotypes.

Scientific Reports
Pengelly, Reuben J RJ; Arias, Liliana L; Martínez, Julio J; Upstill-Goddard, Rosanna R; Seaby, Eleanor G EG; Gibson, Jane J; Ennis, Sarah S; Collins, Andrew A; Briceño, Ignacio I
Publication Date: 2016-07-26

Variant appearance in text: BRAF: E26D
PubMed Link: 27456059
Variant Present in the following documents:
  • srep30457-s2.xls, sheet 2
View BVdb publication page



Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor.

Plos One
Dumble, Melissa M; Crouthamel, Ming-Chih MC; Zhang, Shu-Yun SY; Schaber, Michael M; Levy, Dana D; Robell, Kimberly K; Liu, Qi Q; Figueroa, David J DJ; Minthorn, Elisabeth A EA; Seefeld, Mark A MA; Rouse, Meagan B MB; Rabindran, Sridhar K SK; Heerding, Dirk A DA; Kumar, Rakesh R
Publication Date: 2014

Variant appearance in text: BRAF: E26D
PubMed Link: 24978597
Variant Present in the following documents:
  • pone.0100880.s006.xlsx, sheet 1
View BVdb publication page



Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

Plos One
Bodian, Dale L DL; McCutcheon, Justine N JN; Kothiyal, Prachi P; Huddleston, Kathi C KC; Iyer, Ramaswamy K RK; Vockley, Joseph G JG; Niederhuber, John E JE
Publication Date: 2014

Variant appearance in text: BRAF: E26D
PubMed Link: 24728327
Variant Present in the following documents:
  • pone.0094554.s002.xlsx, sheet 1
  • pone.0094554.s002.xlsx, sheet 3
View BVdb publication page