KCNH2 c.2668T>G ;(p.S890A)

Variant ID: 7-150645556-A-C

NM_000238.3(KCNH2):c.2668T>G;(p.S890A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Identification of small-molecule ion channel modulators in C. elegans channelopathy models.

Nature Communications
Jiang, Qiang Q; Li, Kai K; Lu, Wen-Jing WJ; Li, Shuang S; Chen, Xin X; Liu, Xi-Juan XJ; Yuan, Jie J; Ding, Qiurong Q; Lan, Feng F; Cai, Shi-Qing SQ
Publication Date: 2018-09-26

Variant appearance in text: KCNH2: S890A
PubMed Link: 30258187
Variant Present in the following documents:
  • Main text
  • 41467_2018_Article_6514.pdf
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Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site.

Molecular Pharmacology
Donovan, Alexander J AJ; Lansu, Katherine K; Williams, Jason G JG; Denning, Mitchell F MF; Gentile, Saverio S
Publication Date: 2012-09

Variant appearance in text: Kv11.1: S890A
PubMed Link: 22653970
Variant Present in the following documents:
  • Main text
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Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis.

Biochimica Et Biophysica Acta
Krishnan, Yamini Y; Li, Yan Y; Zheng, Renjian R; Kanda, Vikram V; McDonald, Thomas V TV
Publication Date: 2012-08

Variant appearance in text: HERG: S890A
PubMed Link: 22613764
Variant Present in the following documents:
  • Main text
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PKA phosphorylation of HERG protein regulates the rate of channel synthesis.

American Journal Of Physiology. Heart And Circulatory Physiology
Chen, Jian J; Sroubek, Jakub J; Krishnan, Yamini Y; Li, Yan Y; Bian, Jinsong J; McDonald, Thomas V TV
Publication Date: 2009-05

Variant appearance in text: HERG: S890A
PubMed Link: 19234087
Variant Present in the following documents:
  • Main text
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14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity.

The Embo Journal
Kagan, Anna A; Melman, Yonathan F YF; Krumerman, Andrew A; McDonald, Thomas V TV
Publication Date: 2002-04-15

Variant appearance in text: HERG: S890A
PubMed Link: 11953308
Variant Present in the following documents:
  • Main text
View BVdb publication page