KCNH2 c.2584_2585delinsGC ;(p.L862A)

Variant ID: 7-150645951-AG-GC

NM_000238.3(KCNH2):c.2584_2585delinsGC;(p.L862A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


The hERG potassium channel intrinsic ligand regulates N- and C-terminal interactions and channel closure.

The Journal Of General Physiology
Codding, Sara J SJ; Trudeau, Matthew C MC
Publication Date: 2019-04-01

Variant appearance in text: KCNH2: L862A
PubMed Link: 30425124
Variant Present in the following documents:
  • JGP_201812129.pdf
View BVdb publication page



C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

Plos One
Ng, Chai Ann CA; Ke, Ying Y; Perry, Matthew D MD; Tan, Peter S PS; Hill, Adam P AP; Vandenberg, Jamie I JI
Publication Date: 2013

Variant appearance in text: Kv11.1: L862A
PubMed Link: 24204727
Variant Present in the following documents:
  • Main text
  • pone.0077032.pdf
View BVdb publication page



Structure of the C-terminal region of an ERG channel and functional implications.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Brelidze, Tinatin I TI; Gianulis, Elena C EC; DiMaio, Frank F; Trudeau, Matthew C MC; Zagotta, William N WN
Publication Date: 2013-07-09

Variant appearance in text: Kv11.1: L862A
PubMed Link: 23801759
Variant Present in the following documents:
  • Main text
View BVdb publication page