KCNH2 c.2168G>C ;(p.C723S)

Variant ID: 7-150647486-C-G

NM_000238.3(KCNH2):c.2168G>C;(p.C723S)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide-induced proarrhythmic early afterdepolarizations.

Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology
Al-Owais, Moza M MM; Hettiarachchi, Nishani T NT; Kirton, Hannah M HM; Hardy, Matthew E ME; Boyle, John P JP; Scragg, Jason L JL; Steele, Derek S DS; Peers, Chris C
Publication Date: 2017-11

Variant appearance in text: Kv11.1: C723S
PubMed Link: 28743763
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oxidative modulation of voltage-gated potassium channels.

Antioxidants & Redox Signaling
Sahoo, Nirakar N; Hoshi, Toshinori T; Heinemann, Stefan H SH
Publication Date: 2014-08-20

Variant appearance in text: Kv11.1: C723S
PubMed Link: 24040918
Variant Present in the following documents:
  • Main text
View BVdb publication page



Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels.

The Journal Of Physiology
Kolbe, Katrin K; Schönherr, Roland R; Gessner, Guido G; Sahoo, Nirakar N; Hoshi, Toshinori T; Heinemann, Stefan H SH
Publication Date: 2010-08-15

Variant appearance in text: KCNH2: C723S
PubMed Link: 20547678
Variant Present in the following documents:
  • Main text
View BVdb publication page