Publications:

Pharmacological activation of the hERG K+ channel for the management of the long QT syndrome: A review.

Journal Of Arrhythmia

El Harchi, Aziza A; Brincourt, Oriane O

Publication Date: 2022-08

Variant appearance in text: KCNH2: F656M

PubMed Link: 35936037

Variant Present in the following documents:

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• JOA3-38-554.pdf

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A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias.

The Journal Of Physiology

Yang, Pei-Chi PC; Perissinotti, Laura L LL; López-Redondo, Fernando F; Wang, Yibo Y; DeMarco, Kevin R KR; Jeng, Mao-Tsuen MT; Vorobyov, Igor I; Harvey, Robert D RD; Kurokawa, Junko J; Noskov, Sergei Y SY; Clancy, Colleen E CE

Publication Date: 2017-07-15

Variant appearance in text: KCNH2: F656M

PubMed Link: 28516454

Variant Present in the following documents:

• Main text
• TJP-595-4695.pdf

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Modulation of Kv 11.1 (hERG) channels by 5-(((1H-indazol-5-yl)oxy)methyl)-N-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine (ITP-2), a novel small molecule activator.

British Journal Of Pharmacology

Sale, Harinath H; Roy, Samrat S; Warrier, Jayakumar J; Thangathirupathy, Srinivasan S; Vadari, Yoganand Y; Gopal, Shruthi K SK; Krishnamurthy, Prasad P; Ramarao, Manjunath M

Publication Date: 2017-08

Variant appearance in text: LQT2: F656M

PubMed Link: 28500657

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Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Molecular Pharmacology

Grunnet, Morten M; Abbruzzese, Jennifer J; Sachse, Frank B FB; Sanguinetti, Michael C MC

Publication Date: 2011-01

Variant appearance in text: LQT2: F656M

PubMed Link: 20876384

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Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization.

The Journal Of Physiology

Kurokawa, Junko J; Tamagawa, Masaji M; Harada, Nobuhiro N; Honda, Shin-Ichiro S; Bai, Chang-Xi CX; Nakaya, Haruaki H; Furukawa, Tetsushi T

Publication Date: 2008-06-15

Variant appearance in text: HERG: F656M

PubMed Link: 18440994

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