KCNH2 c.1963A>T ;(p.I655F)

Variant ID: 7-150648191-T-A

NM_000238.3(KCNH2):c.1963A>T;(p.I655F)

This variant was identified in 2 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

The Link between Inactivation and High-Affinity Block of hERG1 Channels.

Molecular Pharmacology
Wu, Wei W; Gardner, Alison A; Sanguinetti, Michael C MC
Publication Date: 2015-06

Variant appearance in text: KCNH2: I655F
PubMed Link: 25855787
Variant Present in the following documents:
  • Main text
View BVdb publication page


Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Chen, Jun J; Seebohm, Guiscard G; Sanguinetti, Michael C MC
Publication Date: 2002-09-17

Variant appearance in text: HERG: I655F
PubMed Link: 12209010
Variant Present in the following documents:
  • Main text
View BVdb publication page