Publications:

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Pharmacological activation of the hERG K+ channel for the management of the long QT syndrome: A review.

Journal Of Arrhythmia

El Harchi, Aziza A; Brincourt, Oriane O

Publication Date: 2022-08

Variant appearance in text: LQT2: M645C

PubMed Link: 35936037

Variant Present in the following documents:

• Main text
• JOA3-38-554.pdf

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Getting to the heart of hERG K(+) channel gating.

The Journal Of Physiology

Perry, Matthew D MD; Ng, Chai-Ann CA; Mann, Stefan A SA; Sadrieh, Arash A; Imtiaz, Mohammad M; Hill, Adam P AP; Vandenberg, Jamie I JI

Publication Date: 2015-06-15

Variant appearance in text: HERG: M645C

PubMed Link: 25820318

Variant Present in the following documents:

• Main text

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Cooperative subunit interactions mediate fast C-type inactivation of hERG1 K+ channels.

The Journal Of Physiology

Wu, Wei W; Gardner, Alison A; Sanguinetti, Michael C MC

Publication Date: 2014-10-15

Variant appearance in text: KCNH2: Met645Cys

PubMed Link: 25063820

Variant Present in the following documents:

• Main text

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Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide.

Molecular Pharmacology

Garg, Vivek V; Stary-Weinzinger, Anna A; Sachse, Frank F; Sanguinetti, Michael C MC

Publication Date: 2011-10

Variant appearance in text: KCNH2: M645C

PubMed Link: 21743002

Variant Present in the following documents:

• Main text

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Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Molecular Pharmacology

Grunnet, Morten M; Abbruzzese, Jennifer J; Sachse, Frank B FB; Sanguinetti, Michael C MC

Publication Date: 2011-01

Variant appearance in text: LQT2: M645C

PubMed Link: 20876384

Variant Present in the following documents:

• Main text

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PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Perry, Matthew M; Sachse, Frank B FB; Abbruzzese, Jennifer J; Sanguinetti, Michael C MC

Publication Date: 2009-11-24

Variant appearance in text: KCNH2: M645C

PubMed Link: 19892732

Variant Present in the following documents:

• Main text

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