KCNH2 c.1915_1916delinsGC ;(p.I639A)

Variant ID: 7-150648565-AT-GC

NM_000238.3(KCNH2):c.1915_1916delinsGC;(p.I639A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Activation of human ether-a-go-go related gene (hERG) potassium channels by small molecules.

Acta Pharmacologica Sinica
Zhou, Ping-zheng PZ; Babcock, Joseph J; Liu, Lian-qing LQ; Li, Min M; Gao, Zhao-bing ZB
Publication Date: 2011-06

Variant appearance in text: LQT2: I639A
PubMed Link: 21623390
Variant Present in the following documents:
  • Main text
View BVdb publication page



PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Perry, Matthew M; Sachse, Frank B FB; Abbruzzese, Jennifer J; Sanguinetti, Michael C MC
Publication Date: 2009-11-24

Variant appearance in text: KCNH2: I639A
PubMed Link: 19892732
Variant Present in the following documents:
  • Main text
View BVdb publication page