Publications:

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Early Steps in C-Type Inactivation of the hERG Potassium Channel.

Journal Of Chemical Information And Modeling

Pettini, Francesco F; Domene, Carmen C; Furini, Simone S

Publication Date: 2022-12-13

Variant appearance in text: HERG: F627Y

PubMed Link: 36512342

Variant Present in the following documents:

• ci2c01028.pdf

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Mechanism of C-type inactivation in the hERG potassium channel.

Science Advances

Li, Jing J; Shen, Rong R; Reddy, Bharat B; Perozo, Eduardo E; Roux, Benoît B

Publication Date: 2021-01

Variant appearance in text: HERG: F627Y

PubMed Link: 33514547

Variant Present in the following documents:

• abd6203.pdf

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Investigating the state dependence of drug binding in hERG channels using a trapped-open channel phenotype.

Scientific Reports

Thouta, Samrat S; Lo, Garman G; Grajauskas, Lukas L; Claydon, Tom T

Publication Date: 2018-03-21

Variant appearance in text: LQT2: F627Y

PubMed Link: 29563525

Variant Present in the following documents:

• Main text
• 41598_2018_Article_23346.pdf

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Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane.

Molecular Biology Of The Cell

Apaja, Pirjo M PM; Foo, Brian B; Okiyoneda, Tsukasa T; Valinsky, William C WC; Barriere, Herve H; Atanasiu, Roxana R; Ficker, Eckhard E; Lukacs, Gergely L GL; Shrier, Alvin A

Publication Date: 2013-12

Variant appearance in text: LQT2: F627Y

PubMed Link: 24152733

Variant Present in the following documents:

• Main text
• 3787.pdf

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Molecular determinants of pentamidine-induced hERG trafficking inhibition.

Molecular Pharmacology

Dennis, Adrienne T AT; Wang, Lu L; Wan, Hanlin H; Nassal, Drew D; Deschenes, Isabelle I; Ficker, Eckhard E

Publication Date: 2012-02

Variant appearance in text: HERG: F627Y

PubMed Link: 22046004

Variant Present in the following documents:

• Main text

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Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.

Biophysical Journal

Es-Salah-Lamoureux, Zeineb Z; Xiong, Ping Yu PY; Goodchild, Samuel J SJ; Ahern, Christopher A CA; Fedida, David D

Publication Date: 2011-08-03

Variant appearance in text: LQT2: F627Y

PubMed Link: 21806934

Variant Present in the following documents:

• Main text

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Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum.

Molecular Pharmacology

Wang, Lu L; Dennis, Adrienne T AT; Trieu, Phan P; Charron, Francois F; Ethier, Natalie N; Hebert, Terence E TE; Wan, Xiaoping X; Ficker, Eckhard E

Publication Date: 2009-04

Variant appearance in text: HERG: F627Y

PubMed Link: 19139152

Variant Present in the following documents:

• Main text

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Na+ permeation and block of hERG potassium channels.

The Journal Of General Physiology

Gang, Hongying H; Zhang, Shetuan S

Publication Date: 2006-07

Variant appearance in text: HERG: F627Y

PubMed Link: 16769794

Variant Present in the following documents:

• Main text
• jgp1280055.pdf

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