KCNH2 c.1762_1763delinsTG ;(p.N588C)

Variant ID: 7-150648718-TT-CA

NM_000238.3(KCNH2):c.1762_1763delinsTG;(p.N588C)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Selectivity filter modalities and rapid inactivation of the hERG1 channel.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Miranda, Williams E WE; DeMarco, Kevin R KR; Guo, Jiqing J; Duff, Henry J HJ; Vorobyov, Igor I; Clancy, Colleen E CE; Noskov, Sergei Yu SY
Publication Date: 2020-02-11

Variant appearance in text: KCNH2: N588C
PubMed Link: 31980532
Variant Present in the following documents:
  • Main text
View BVdb publication page



BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1.

Biophysical Journal
Zhang, Mei M; Korolkova, Yuliya V YV; Liu, Jie J; Jiang, Min M; Grishin, Eugene V EV; Tseng, Gea-Ny GN
Publication Date: 2003-05

Variant appearance in text: HERG: N588C
PubMed Link: 12719233
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural and functional role of the extracellular s5-p linker in the HERG potassium channel.

The Journal Of General Physiology
Liu, Jie J; Zhang, Mei M; Jiang, Min M; Tseng, Gea-Ny GN
Publication Date: 2002-11

Variant appearance in text: HERG: N588C
PubMed Link: 12407082
Variant Present in the following documents:
  • Main text
  • 20028687.pdf
View BVdb publication page