Publications:

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Deciphering Common Long QT Syndrome Using CRISPR/Cas9 in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Frontiers In Cardiovascular Medicine

Song, Yongfei Y; Zheng, Zequn Z; Lian, Jiangfang J

Publication Date: 2022

Variant appearance in text: LQT2: A561P

PubMed Link: 35647048

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• fcvm-09-889519.pdf

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Urine-derived induced pluripotent/neural stem cells for modeling neurological diseases.

Cell & Bioscience

Shi, Tianyuan T; Cheung, Martin M

Publication Date: 2021-05-13

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PubMed Link: 33985584

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• 13578_2021_Article_594.pdf

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Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome.

Frontiers In Pharmacology

Brewer, Kathryn R KR; Kuenze, Georg G; Vanoye, Carlos G CG; George, Alfred L AL; Meiler, Jens J; Sanders, Charles R CR

Publication Date: 2020

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PubMed Link: 32431610

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Urine-Derived Induced Pluripotent Stem Cells in Cardiovascular Disease.

Cardiology Research And Practice

Huang, Ping P; Li, Yibin Y; Nasser, M I MI; Guo, Huiming H; Huang, Huanlei H; Zhao, Mingyi M; Zhu, Ping P

Publication Date: 2020

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PubMed Link: 32377426

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Left Ventricular Noncompaction and Congenital Heart Disease Increases the Risk of Congestive Heart Failure.

Journal Of Clinical Medicine

Hirono, Keiichi K; Hata, Yukiko Y; Miyao, Nariaki N; Okabe, Mako M; Takarada, Shinya S; Nakaoka, Hideyuki H; Ibuki, Keijiro K; Ozawa, Sayaka S; Yoshimura, Naoki N; Nishida, Naoki N; Ichida, Fukiko F; Lvnc Study Collaborators,

Publication Date: 2020-03-13

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PubMed Link: 32183154

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The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases.

International Journal Of Molecular Sciences

Pourrier, Marc M; Fedida, David D

Publication Date: 2020-01-19

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PubMed Link: 31963859

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R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome.

Scientific Reports

Mesquita, Fernanda C P FCP; Arantes, Paulo C PC; Kasai-Brunswick, Tais H TH; Araujo, Dayana S DS; Gubert, Fernanda F; Monnerat, Gustavo G; Silva Dos Santos, Danúbia D; Neiman, Gabriel G; Leitão, Isabela C IC; Barbosa, Raiana A Q RAQ; Coutinho, Jorge L JL; Vaz, Isadora M IM; Dos Santos, Marcus N MN; Borgonovo, Tamara T; Cruz, Fernando E S FES; Miriuka, Santiago S; Medei, Emiliano H EH; Campos de Carvalho, Antonio C AC; Carvalho, Adriana B AB

Publication Date: 2019-12-16

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PubMed Link: 31844156

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Episomal Induced Pluripotent Stem Cells: Functional and Potential Therapeutic Applications.

Cell Transplantation

Wang, Aline Yen Ling AYL; Loh, Charles Yuen Yung CYY

Publication Date: 2019-12

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PubMed Link: 31722555

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Genome Editing and Induced Pluripotent Stem Cell Technologies for Personalized Study of Cardiovascular Diseases.

Current Cardiology Reports

Chun, Young Wook YW; Durbin, Matthew D MD; Hong, Charles C CC

Publication Date: 2018-04-17

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PubMed Link: 29666931

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Urine-Derived Stem Cells: The Present and the Future.

Stem Cells International

Ji, Xiaoli X; Wang, Min M; Chen, Fang F; Zhou, Junmei J

Publication Date: 2017

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PubMed Link: 29250119

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Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.

Cellular And Molecular Life Sciences : Cmls

Giacomelli, E E; Mummery, C L CL; Bellin, M M

Publication Date: 2017-10

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PubMed Link: 28573431

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Molecular Pathophysiology of Congenital Long QT Syndrome.

Physiological Reviews

Bohnen, M S MS; Peng, G G; Robey, S H SH; Terrenoire, C C; Iyer, V V; Sampson, K J KJ; Kass, R S RS

Publication Date: 2017-01

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PubMed Link: 27807201

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Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

Physiological Reviews

Matsa, Elena E; Ahrens, John H JH; Wu, Joseph C JC

Publication Date: 2016-07

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PubMed Link: 27335446

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Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.

Nature Reviews. Cardiology

Chen, Ian Y IY; Matsa, Elena E; Wu, Joseph C JC

Publication Date: 2016-06

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PubMed Link: 27009425

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In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.

Journal Of Molecular And Cellular Cardiology

Romero, Lucia L; Trenor, Beatriz B; Yang, Pei-Chi PC; Saiz, Javier J; Clancy, Colleen E CE

Publication Date: 2015-10

Variant appearance in text: LQT2: A561P

PubMed Link: 26859003

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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome.

Journal Of The American Heart Association

Jouni, Mariam M; Si-Tayeb, Karim K; Es-Salah-Lamoureux, Zeineb Z; Latypova, Xenia X; Champon, Benoite B; Caillaud, Amandine A; Rungoat, Anais A; Charpentier, Flavien F; Loussouarn, Gildas G; Baró, Isabelle I; Zibara, Kazem K; Lemarchand, Patricia P; Gaborit, Nathalie N

Publication Date: 2015-09-01

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PubMed Link: 26330336

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Large-scale mutational analysis of Kv11.1 reveals molecular insights into type 2 long QT syndrome.

Nature Communications

Anderson, Corey L CL; Kuzmicki, Catherine E CE; Childs, Ryan R RR; Hintz, Caleb J CJ; Delisle, Brian P BP; January, Craig T CT

Publication Date: 2014-11-24

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PubMed Link: 25417810

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In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome.

Journal Of Molecular And Cellular Cardiology

Romero, Lucia L; Trenor, Beatriz B; Yang, Pei-Chi PC; Saiz, Javier J; Clancy, Colleen E CE

Publication Date: 2014-07

Variant appearance in text: HERG: A561P

PubMed Link: 24631769

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Pharmacological and electrophysiological characterization of nine, single nucleotide polymorphisms of the hERG-encoded potassium channel.

British Journal Of Pharmacology

Männikkö, Roope R; Overend, G G; Perrey, C C; Gavaghan, C L CL; Valentin, J-P JP; Morten, J J; Armstrong, M M; Pollard, C E CE

Publication Date: 2010-01

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PubMed Link: 19673885

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