Publications:

New potential binding determinant for hERG channel inhibitors.

Scientific Reports

Saxena, P P; Zangerl-Plessl, E-M EM; Linder, T T; Windisch, A A; Hohaus, A A; Timin, E E; Hering, S S; Stary-Weinzinger, A A

Publication Date: 2016-04-12

Variant appearance in text: HERG: M554A

PubMed Link: 27067805

Variant Present in the following documents:

• srep24182.pdf

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ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels.

Molecular Pharmacology

Garg, Vivek V; Stary-Weinzinger, Anna A; Sanguinetti, Michael C MC

Publication Date: 2013-04

Variant appearance in text: KCNH2: M554A

PubMed Link: 23319419

Variant Present in the following documents:

• Main text

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Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Molecular Pharmacology

Grunnet, Morten M; Abbruzzese, Jennifer J; Sachse, Frank B FB; Sanguinetti, Michael C MC

Publication Date: 2011-01

Variant appearance in text: LQT2: M554A

PubMed Link: 20876384

Variant Present in the following documents:

• Main text

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