KCNH2 c.1657_1658delinsGC ;(p.L553A)

Variant ID: 7-150648823-AG-GC

NM_000238.3(KCNH2):c.1657_1658delinsGC;(p.L553A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.

Molecular Pharmacology
Gardner, Alison A; Wu, Wei W; Thomson, Steven S; Zangerl-Plessl, Eva-Maria EM; Stary-Weinzinger, Anna A; Sanguinetti, Michael C MC
Publication Date: 2017-10

Variant appearance in text: KCNH2: L553A
PubMed Link: 28705808
Variant Present in the following documents:
  • Main text
View BVdb publication page



C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.

Molecular Pharmacology
Gardner, Alison A; Sanguinetti, Michael C MC
Publication Date: 2015-07

Variant appearance in text: KCNH2: L553A
PubMed Link: 25888115
Variant Present in the following documents:
  • Main text
View BVdb publication page



Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243.

Molecular Pharmacology
Wu, Wei W; Gardner, Alison A; Sanguinetti, Michael C MC
Publication Date: 2015

Variant appearance in text: KCNH2: L553A
PubMed Link: 25519838
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Perry, Matthew M; Sachse, Frank B FB; Sanguinetti, Michael C MC
Publication Date: 2007-08-21

Variant appearance in text: KCNH2: L553A
PubMed Link: 17693551
Variant Present in the following documents:
  • Main text
View BVdb publication page