KCNH2 c.1636G>T ;(p.G546C)

Variant ID: 7-150648845-C-A

NM_000238.3(KCNH2):c.1636G>T;(p.G546C)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology
Li, Na N; Wang, Jiahong J; Zhan, Xianquan X
Publication Date: 2021

Variant appearance in text: KCNH2: 1636G>T; Gly546Cys
PubMed Link: 34887858
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell
Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD
Publication Date: 2018-05-14

Variant appearance in text: KCNH2: G546C
PubMed Link: 29657128
Variant Present in the following documents:
  • mmc3.xlsx, sheet 3
View BVdb publication page



Voltage-dependent gating of HERG potassium channels.

Frontiers In Pharmacology
Cheng, Yen May YM; Claydon, Tom W TW
Publication Date: 2012

Variant appearance in text: Kv11.1: G546C
PubMed Link: 22586397
Variant Present in the following documents:
  • Main text
View BVdb publication page



HERG potassium channel regulation by the N-terminal eag domain.

Cellular Signalling
Gustina, Ahleah S AS; Trudeau, Matthew C MC
Publication Date: 2012-08

Variant appearance in text: LQT2: G546C
PubMed Link: 22522181
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.

Plos One
Fernández-Trillo, Jorge J; Barros, Francisco F; Machín, Angeles A; Carretero, Luis L; Domínguez, Pedro P; de la Peña, Pilar P
Publication Date: 2011

Variant appearance in text: HERG: G546C
PubMed Link: 21935437
Variant Present in the following documents:
  • pone.0024674.pdf
View BVdb publication page



Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.

Biophysical Journal
Alonso-Ron, Carlos C; de la Peña, Pilar P; Miranda, Pablo P; Domínguez, Pedro P; Barros, Francisco F
Publication Date: 2008-05-15

Variant appearance in text: HERG: G546C
PubMed Link: 18222997
Variant Present in the following documents:
  • Main text
View BVdb publication page



Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels.

The Journal Of General Physiology
Wang, J J; Trudeau, M C MC; Zappia, A M AM; Robertson, G A GA
Publication Date: 1998-11

Variant appearance in text: HERG: G546C
PubMed Link: 9806971
Variant Present in the following documents:
  • Main text
  • GP-7771.pdf
View BVdb publication page