KCNH2 c.1625A>G ;(p.Y542C)

Variant ID: 7-150648856-T-C

NM_000238.3(KCNH2):c.1625A>G;(p.Y542C)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.

Molecular Pharmacology
Gardner, Alison A; Sanguinetti, Michael C MC
Publication Date: 2015-07

Variant appearance in text: KCNH2: Y542C
PubMed Link: 25888115
Variant Present in the following documents:
  • Main text
View BVdb publication page



Getting to the heart of hERG K(+) channel gating.

The Journal Of Physiology
Perry, Matthew D MD; Ng, Chai-Ann CA; Mann, Stefan A SA; Sadrieh, Arash A; Imtiaz, Mohammad M; Hill, Adam P AP; Vandenberg, Jamie I JI
Publication Date: 2015-06-15

Variant appearance in text: Kv11.1: Y542C
PubMed Link: 25820318
Variant Present in the following documents:
  • Main text
View BVdb publication page



Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.

The Journal Of General Physiology
Gianulis, Elena C EC; Liu, Qiangni Q; Trudeau, Matthew C MC
Publication Date: 2013-10

Variant appearance in text: HERG: Y542C
PubMed Link: 24043860
Variant Present in the following documents:
  • JGP_201310995.pdf
View BVdb publication page



Voltage-dependent gating of HERG potassium channels.

Frontiers In Pharmacology
Cheng, Yen May YM; Claydon, Tom W TW
Publication Date: 2012

Variant appearance in text: Kv11.1: Y542C
PubMed Link: 22586397
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.

Plos One
Fernández-Trillo, Jorge J; Barros, Francisco F; Machín, Angeles A; Carretero, Luis L; Domínguez, Pedro P; de la Peña, Pilar P
Publication Date: 2011

Variant appearance in text: HERG: Y542C
PubMed Link: 21935437
Variant Present in the following documents:
  • pone.0024674.pdf
View BVdb publication page



Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.

Biophysical Journal
Alonso-Ron, Carlos C; de la Peña, Pilar P; Miranda, Pablo P; Domínguez, Pedro P; Barros, Francisco F
Publication Date: 2008-05-15

Variant appearance in text: HERG: Y542C
PubMed Link: 18222997
Variant Present in the following documents:
  • Main text
View BVdb publication page