Publications:

The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.

Biophysical Journal

Dou, Ying Y; Macdonald, Logan C LC; Wu, Yue Y; Fedida, David D

Publication Date: 2017-11-07

Variant appearance in text: Kv11.1: R541A

PubMed Link: 29117522

Variant Present in the following documents:

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Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.

The Journal Of Biological Chemistry

Ng, Chai-Ann CA; Gravel, Andrée E AE; Perry, Matthew D MD; Arnold, Alexandre A AA; Marcotte, Isabelle I; Vandenberg, Jamie I JI

Publication Date: 2016-08-12

Variant appearance in text: Kv11.1: R541A

PubMed Link: 27317659

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Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.

The Journal Of General Physiology

Gianulis, Elena C EC; Liu, Qiangni Q; Trudeau, Matthew C MC

Publication Date: 2013-10

Variant appearance in text: HERG: R541A

PubMed Link: 24043860

Variant Present in the following documents:

• JGP_201310995.pdf

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The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.

Plos One

Ng, Chai Ann CA; Perry, Matthew D MD; Tan, Peter S PS; Hill, Adam P AP; Kuchel, Philip W PW; Vandenberg, Jamie I JI

Publication Date: 2012

Variant appearance in text: HERG: R541A

PubMed Link: 22359612

Variant Present in the following documents:

• Main text
• pone.0031640.pdf

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Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.

Biophysical Journal

Alonso-Ron, Carlos C; de la Peña, Pilar P; Miranda, Pablo P; Domínguez, Pedro P; Barros, Francisco F

Publication Date: 2008-05-15

Variant appearance in text: HERG: R541A

PubMed Link: 18222997

Variant Present in the following documents:

• Main text

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