KCNH2 c.1609_1610delinsGC ;(p.R537A)

Variant ID: 7-150648871-CG-GC

NM_000238.3(KCNH2):c.1609_1610delinsGC;(p.R537A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.

Biophysical Journal
Dou, Ying Y; Macdonald, Logan C LC; Wu, Yue Y; Fedida, David D
Publication Date: 2017-11-07

Variant appearance in text: Kv11.1: R537A
PubMed Link: 29117522
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.

The Journal Of Biological Chemistry
Ng, Chai-Ann CA; Gravel, Andrée E AE; Perry, Matthew D MD; Arnold, Alexandre A AA; Marcotte, Isabelle I; Vandenberg, Jamie I JI
Publication Date: 2016-08-12

Variant appearance in text: Kv11.1: R537A
PubMed Link: 27317659
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

The Journal Of General Physiology
Perry, Matthew D MD; Wong, Sophia S; Ng, Chai Ann CA; Vandenberg, Jamie I JI
Publication Date: 2013-09

Variant appearance in text: Kv11.1: R537A
PubMed Link: 23980196
Variant Present in the following documents:
  • supp_jgp.201310975_JGP_201310975_sm.pdf
View BVdb publication page