KCNH2 c.1604T>C ;(p.V535A)

Variant ID: 7-150648877-A-G

NM_000238.3(KCNH2):c.1604T>C;(p.V535A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.

Biophysical Journal
Dou, Ying Y; Macdonald, Logan C LC; Wu, Yue Y; Fedida, David D
Publication Date: 2017-11-07

Variant appearance in text: Kv11.1: V535A
PubMed Link: 29117522
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.

The Journal Of Biological Chemistry
Ng, Chai-Ann CA; Gravel, Andrée E AE; Perry, Matthew D MD; Arnold, Alexandre A AA; Marcotte, Isabelle I; Vandenberg, Jamie I JI
Publication Date: 2016-08-12

Variant appearance in text: Kv11.1: V535A
PubMed Link: 27317659
Variant Present in the following documents:
  • Main text
View BVdb publication page



A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris.

Scientific Reports
Dhillon, Mandeep S MS; Cockcroft, Christopher J CJ; Munsey, Tim T; Smith, Kathrine J KJ; Powell, Andrew J AJ; Carter, Paul P; Wrighton, David C DC; Rong, Hong-lin HL; Yusaf, Shahnaz P SP; Sivaprasadarao, Asipu A
Publication Date: 2014-02-26

Variant appearance in text: KCNH2: V535A
PubMed Link: 24569544
Variant Present in the following documents:
  • Main text
  • srep04201.pdf
View BVdb publication page



Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

The Journal Of General Physiology
Perry, Matthew D MD; Wong, Sophia S; Ng, Chai Ann CA; Vandenberg, Jamie I JI
Publication Date: 2013-09

Variant appearance in text: Kv11.1: V535A
PubMed Link: 23980196
Variant Present in the following documents:
  • Main text
  • JGP_201310975.pdf
  • supp_jgp.201310975_JGP_201310975_sm.pdf
View BVdb publication page