KCNH2 c.1379A>C ;(p.D460A)

Variant ID: 7-150649691-T-G

NM_000238.3(KCNH2):c.1379A>C;(p.D460A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.

Molecular Pharmacology
Gardner, Alison A; Wu, Wei W; Thomson, Steven S; Zangerl-Plessl, Eva-Maria EM; Stary-Weinzinger, Anna A; Sanguinetti, Michael C MC
Publication Date: 2017-10

Variant appearance in text: KCNH2: D460A
PubMed Link: 28705808
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular determinants of pentamidine-induced hERG trafficking inhibition.

Molecular Pharmacology
Dennis, Adrienne T AT; Wang, Lu L; Wan, Hanlin H; Nassal, Drew D; Deschenes, Isabelle I; Ficker, Eckhard E
Publication Date: 2012-02

Variant appearance in text: HERG: D460A
PubMed Link: 22046004
Variant Present in the following documents:
  • Main text
View BVdb publication page



Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating.

Channels (Austin, Tex.)
Lin, Meng Chin A MC; Papazian, Diane M DM
Publication Date: 2007

Variant appearance in text: HERG: D460A
PubMed Link: 18690045
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation.

The Journal Of Physiology
Fernandez, David D; Ghanta, Azad A; Kinard, Krista I KI; Sanguinetti, Michael C MC
Publication Date: 2005-09-15

Variant appearance in text: HERG: D460A
PubMed Link: 15975984
Variant Present in the following documents:
  • Main text
View BVdb publication page