KCNH2 c.1345_1346delinsGT ;(p.C449V)

Variant ID: 7-150649724-CA-AC

NM_000238.3(KCNH2):c.1345_1346delinsGT;(p.C449V)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.

Pflugers Archiv : European Journal Of Physiology
de la Peña, Pilar P; Domínguez, Pedro P; Barros, Francisco F
Publication Date: 2018-07

Variant appearance in text: Kv11.1: C449V
PubMed Link: 29572566
Variant Present in the following documents:
  • Main text
  • 424_2018_Article_2135.pdf
View BVdb publication page



Gating mechanism of Kv11.1 (hERG) K+ channels without covalent connection between voltage sensor and pore domains.

Pflugers Archiv : European Journal Of Physiology
de la Peña, Pilar P; Domínguez, Pedro P; Barros, Francisco F
Publication Date: 2018-03

Variant appearance in text: Kv11.1: C449V
PubMed Link: 29270671
Variant Present in the following documents:
  • Main text
  • 424_2017_Article_2093.pdf
View BVdb publication page



Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels.

The Journal Of General Physiology
Wang, Zhuren Z; Dou, Ying Y; Goodchild, Samuel J SJ; Es-Salah-Lamoureux, Zeineb Z; Fedida, David D
Publication Date: 2013-04

Variant appearance in text: Kv11.1: C449V
PubMed Link: 23478995
Variant Present in the following documents:
  • JGP_201210942.pdf
View BVdb publication page



Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening.

Plos One
Es-Salah-Lamoureux, Zeineb Z; Fougere, Robert R; Xiong, Ping Yu PY; Robertson, Gail A GA; Fedida, David D
Publication Date: 2010-05-28

Variant appearance in text: HERG: C449V
PubMed Link: 20526358
Variant Present in the following documents:
  • pone.0010876.pdf
View BVdb publication page